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HIV Infection/Disease
  Adipose Tissue Metabolic Disorders  
Adipose Tissue Alterations: General
Abdominal Obesity
Fat Redistribution



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Last Update: February 11, 2015
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Adipose Tissue Alterations: General

        Journal Papers, Abstracts, and Commentaries


Bariatric surgery: An HIV-positive patient's successful journey.
Eddy F, Elvin S, Sanmani L.
Int J STD AIDS. 2015 Feb 6.

Obesity in HIV-infected patients in France: Prevalence and surgical treatment options.
Pourcher G, Costagliola D, Martinez V.
J Visc Surg. 2015 Feb 4.

Multiple frequency bioimpedance is an adequate tool to assess total and regional fat mass in HIV-positive patients but not to diagnose HIV-associated lipoatrophy: a pilot study.
Pérez-Matute P, Pérez-Martínez L, Blanco JR,
J Int AIDS Soc. 2013 Dec 27;16:18609.

CD8 T-cell activation is associated with lipodystrophy and visceral fat accumulation in ART-treated virologically-suppressed HIV-infected patients.
Guaraldi G, Luzi K, Bellistrì GM,  et al

J Acquir Immune Defic Syndr
. 2013 Oct 14.


Surrogate markers of visceral adipose tissue in treated HIV-infected patients: accuracy of waist circumference determination.
Falutz J, Rosenthall L, Kotler D, et al

. 2013 Sep 22.


In Vitro and In Vivo Effects of IGF-I on Adiposity in HIV-associated Metabolic Disease: A Pilot Study.
Kim RJ, Vaghani S, Zifchak LM, et al
Arch Med Res. 2013 Jul 15

Central/Peripheral Fat Mass Ratio Is Associated With Increased Risk of Hypertension in HIV-Infected Patients.
Freitas P, Carvalho D, Santos AC,  et al

J Clin Hypertens (Greenwich)
. 2012 Sep;14(9):593

Obesity and the risk and outcome of infection.
Huttunen R, Syrjänen J
Int J Obes (Lond). 2012 May 1

Management of Fat Accumulation in Patients with HIV Infection.
Falutz J.
Curr HIV/AIDS Rep. 2011 Jul 8..

Adipose Tissue as a Target of HIV-1 Antiretroviral Drugs. Potential Consequences on
Metabolic Regulations.
Caron-Debarle M, Boccara F, Lagathu C,  et al

Curr Pharm Des
. 2010 Aug 5

Treatment Options for HIV-Associated Central Fat Accumulation.
Cofrancesco J, Freedland E, McComsey G. 

AIDS Patient Care STDS
. 2008 Dec 4.

Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy -
associated lipodystrophy.

Sevastianova K, Sutinen J, Kannisto K, et al

Am J Physiol Endocrinol Metab. 2008 Apr 22
HIV and HIV treatment: effects on fats, glucose and lipids.
Gkrania-Klotsas E, Klotsas AE.

Br Med Bull.
2007 Nov 2
Ultrasonography and Anthropometry for Measuring Regional Body Fat in HIV-Infected
Padilla S, Gallego JA, Masiá M, et al
Curr HIV Res. 2007 Sep;5(5):459-66.

Strategies in the treatment of HIV-1-associated adipose redistribution syndromes.
Mar Gutierrez MD, Mateo G, Domingo P.
Expert Opin Pharmacother. 2007 Aug;8(12):1871-1884.
Long-Term Body Fat Outcomes in Antiretroviral-Naive Participants Randomized to Nelfinavir
or Efavirenz or Both Plus Dual Nucleosides: Dual X-Ray Absorptiometry Results From A5005s,
a Substudy of Adult Clinical Trials Group 384.

Dubé MP, Komarow L, Mulligan K, et al

J Acquir Immune Defic Syndr.
2007 Jun 21;
Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based
highly active antiretroviral therapy.
Chaparro J, Reeds DN, Wen W, et al
Metabolism. 2005 May;54(5):561-7
Chronic loss of subcutaneous adipose tissue in HIV-associated lipodystrophy may not
be associated with accelerated apoptosis.
Mynarcik D, Wei LX, Komaroff E, et al 
J Acquir Immune Defic Syndr. 2005 Mar 1;38(3):367-71.
Interventions for visceral adiposity associated with human immunodeficiency virus:
application of a method for assessing efficacy.
Engelson ES.

Clin Infect Dis.
2003;37 Suppl 2:S96-100.

Incidence of Adipose Tissue Alterations in First-Line Antiretroviral Therapy:
The LipoICoNa Study.
Galli M, Cozzi-Lepri A, Ridolfo AL, et al.

Arch Intern Med
2002 Dec 9;162(22):2621-8

Use of a Durnin-Womersley formula to estimate change in subcutaneous fat
content in HIV-infected subjects.
Andrade S, Lan SJ, Engelson ES, et al.
Am J Clin Nutr 2002 Mar;75(3):587-92

Evidence of nucleoside analogue reverse transcriptase inhibitor--associated
genetic and structural defects of mitochondria in adipose tissue of HIV-infected
Walker UA, Bickel M, Lutke Volksbeck SI, et al.
J Acquir Immune Defic Syndr 2002 Feb 1;29(2):117-21

Long-term changes in adipose tissue in human disease.
Pond CM.
Proc Nutr Soc 2001 Aug;60(3):365-74


         Conference Reports, Abstracts, and Posters

Peri-renal fat diameter is related to intima media thickness and renal arterial resistance index in
HIV-1 infected patients
Grima PF, Chiavaroli R, Grima P, et al 
(Ninth International Congress on Drug Therapy in HIV Infection)
Low Levels of Lipin mRNA Expression in Adipose Tissues from HIV-infected
Patients with Lipodystrophy
B Lindegaard, L Frydelund-Larsen


HIV-associated lipomatosis. An emerging adverse event of antiretroviral treatment,
related to dysmetabolism?

R Manfredi, L Calza, F Chiodo

Antiretroviral Therapy (ART)-Associated Adipose Tissue Alterations in Women:
a Prospective Study


Abdominal Obesity


        Journal Papers, Abstracts, and Commentaries


  Effects of Testosterone Supplementation on Whole Body and Regional Fat Mass and
Distribution in HIV-Infected Men with Abdominal Obesity.
Bhasin S, Parker RA, Sattler F, et al
J Clin Endocrinol Metab. 2006 Dec 12



Journal Papers, Abstracts, and Commentaries

  Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia,
and fat redistribution in human immunodeficiency virus-infected patients treated
with highly active antiretroviral therapy.

Addy CL, Gavrila A, Tsiodras S, et al.

J Clin Endocrinol Metab
2003 Feb;88(2):627-36




        Journal Papers, Abstracts, and Commentaries

  Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy
are associated with serum concentrations of leptin.

Nagy GS, Tsiodras S, Martin LD, et al.

Clin Infect Dis
2003 Mar 15;36(6):795-802


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