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Last Update:  May 10, 2017
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New and Noteworthy
     

May 2017
 
 

April 2017

 

 


General Reports
 

        Journal Papers, Abstracts, and Commentaries

 
New weapons in the Cryptococcus infection toolkit.
Taylor-Smith LM, May RC.

Curr Opin Microbiol
.
2016 Aug 11
Abstract

End-Stage Liver Disease Is a Strong Predictor of Early Mortality in Cryptococcosis.
Spec A, Raval K, Powderly WG.

Open Forum Infect Dis
. 2015 Dec 15;3(1):ofv197.
Abstract

Cryptococcus neoformans-Induced Macrophage Lysosome Damage Crucially Contributes to Fungal Virulence.
Davis MJ, Eastman AJ, Qiu Y,  et al
J Immunol. 2015 Jan 30
Abstract

FULL-TEXT ARTICLE
Images in clinical medicine. Disseminated cryptococcosis.
Martin-Blondel G, Ysebaert L.
N Engl J Med. 2014 May 1;370(18):1741.
Paper

The Cryptococcus neoformans Transcriptome at the Site of Human Meningitis.
Chen Y, Toffaletti DL, Tenor JL,  et al
 
MBio
. 2014 Feb 4;5(1).

Abstract

FULL-TEXT ARTICLE
Cryptococcus neoformans Ex Vivo Capsule Size Is Associated With Intracranial Pressure and Host Immune Response in HIV-associated Cryptococcal Meningitis.
Robertson EJ, Najjuka G, Rolfes MA,  et al
J Infect Dis
. 2014 Jan;209(1):74-82.
Paper

Role of ferric reductases in iron acquisition and virulence in the fungal pathogen Cryptococcus neoformans.
Saikia S, Oliveira D, Hu G, Kronstad J.
Infect Immun. 2013 Dec 9
Abstract

Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment.
Gullo FP, Rossi SA, Sardi Jde C, sf al
Eur J Clin Microbiol Infect Dis
. 2013 Nov;32(11):1377-91.

Abstract

Old Cryptococcus neoformans Cells Contribute to Virulence in Chronic Cryptococcosis.
Bouklas T, Pechuan X, Goldman DL,  et al
MBio
. 2013 Aug 13;4(4).
Abstract

Cryptococcosis-IRIS is associated with lower Cryptococcus-specific IFN-gamma responses before antiretroviral therapy but not higher T-cell responses during therapy.
Chang CC, Lim A, Omarjee S,  et al  
J Infect Dis
. 2013 Jun 12
Abstract

FULL-TEXT ARTICLE
Predictors of Mortality and Differences in Clinical Features among Patients with Cryptococcosis According to Immune Status.
Brizendine KD, Baddley JW, Pappas PG.
PLoS One. 2013;8(3):e60431.
Paper

Cryptococcosis.
Negroni R.

Clin Dermatol
  2012 Nov;30(6):599-609.
Abstract

CNS-Immune Reconstitution Inflammatory Syndrome in the Setting of HIV Infection, Part 1: Overview and Discussion of Progressive Multifocal Leukoencephalopathy-Immune Reconstitution Inflammatory Syndrome and Cryptococcal-Immune Reconstitution Inflammatory Syndrome.
Post MJ, Thurnher MM, Clifford DB, Nath A, et al
AJNR Am J Neuroradiol
. 2012 Jul 12.
Abstract

FULL-TEXT ARTICLE
Differences in Nitrogen Metabolism between Cryptococcus neoformans and C. gattii, the Two Etiologic Agents of Cryptococcosis.
Ngamskulrungroj P, Chang Y, Roh J,  etal

PLoS One
. 2012;7(3):e34258
Paper

FULL-TEXT ARTICLE
Unraveling the unique structure and biosynthesis pathway of N-linked glycans in the human fungal pathogen Cryptococcus neoformans by glycomics analysis.
Park JN, Lee DJ, Kwon O,  et al
J Biol Chem. 2012 Apr 12.
Paper

FULL-TEXT ARTICLE
Evidence that the Human Pathogenic Fungus Cryptococcus neoformans var. grubii May Have
Evolved in Africa.
Litvintseva AP, Carbone I, Rossouw J,  et al

PLoS One
. 2011 May 11;6(5):e19688
Paper

An update on Cryptococcus among HIV-infected patients.
Warkentien T, Crum-Cianflone NF.

Int J STD AIDS
.
2010 Oct;21(10):679-84
Abstract

Cryptococcal interactions with the host immune system.
Voelz K, May RC.

Eukaryot Cell
. 2010 Jun;9(6):835-46
Abstract

Risk factors for mortality from primary cryptococcosis in patients with HIV.
Sajadi MM, Roddy KM, Chan-Tack KM, Forrest GN.
Postgrad Med. 2009 Mar;121(2):107-13
Abstract


Cryptococcosis
Yoshida K, Shoji H, Niki Y. et al

Nippon Rinsho
. 2008 Dec;66(12):2350-5.
Abstract
 
Cryptococcosis
Osuna A, Carragoso A, Lemos A, et al
Acta Med Port. 2008 May-Jun;21(3):307-13.
Abstract
 
Profile of Central Nervous System Disease in HIV/AIDS Patients With Special Reference to
Cryptococcal Infections.
Wadhwa A, Kaur R, Bhalla P.

Neurologist.
2008 Jul;14(4):247-51
Abstract
 
FULL TEXT ARTICLE
AIDS patient death caused by novel Cryptococcus neoformans × C. gattii hybrid.
Bovers M, Hagen F, Kuramae EE,  et al.
Emerg Infect Dis  . Vol 14, N07–July 2008
Paper
 

Pathogenesis
 

       Journal Papers, Abstracts, and Commentaries

 
New Insights on the Pathogenesis of Invasive Cryptococcus neoformans Infection.
Eisenman HC, Casadevall A, McClelland EE.

Curr Infect Dis Rep. 2007 Nov;9(6):457-64
Abstract
 
Iron and fungal pathogenesis: a case study with Cryptococcus neoformans.
Jung WH, Kronstad JW.
 
Cell Microbiol.
2007 Nov 27
Abstract
 
Phenotypic switching and its implications for the pathogenesis of Cryptococcus neoformans.
Jain N, Guerrero A, Fries BC.
FEMS Yeast Res. 2006 Jun;6(4):480-8.
Abstract
 
A clinical study of cryptococcal meningitis--sequential changes of cryptococcal
antigen titers
Kishi K, Homma S, Nakatani T, et al

Kansenshogaku Zasshi
2003 Mar;77(3):150-7
Abstract

Phenotypic switching in Cryptococcus neoformans.
Fries BC, Goldman DL, Casadevall A.
Microbes Infect 2002 Nov;4(13):1345-52
Abstract

Pathogenesis of cryptococcal meningitis
Neuville S, Dromer F, Chretien F
Ann Med Interne (Paris) 2002 Sep;153(5):323-8
Abstract

 

Prevention
 

      Journal Papers, Abstracts, and Commentaries

 
Primary Prophylaxis for Cryptococcosis With Fluconazole in Human Immunodeficiency Virus-Infected Patients With CD4 T-Cell Counts <100 Cells/µL and Receiving Antiretroviral Therapy.
Sungkanuparph S, Savetamornkul C, Pattanapongpaiboon W.
Clin Infect Dis. 2017 Apr 1;64(7):967-970.
Abstract

Role of Complement in Protection Against Cryptococcus gattii Infection.
Mershon KL, Vasuthasawat A, Lawson GW, et al
 
Infect Immun
. 2008 Dec 29.
Abstract
 

Prevention of cryptococcosis in HIV-infected patients with limited access to highly active
antiretroviral therapy: evidence for primary azole prophylaxis.
Caney P, Stephens D, Rimland D.
HIV Med. 2005 Jul;6(4):253-9
Abstract
 

Diagnosis/Testing
 

     Journal Papers, Abstracts, and Commentaries

 
Examination of cryptococcal glucuronoxylomannan antigen in bronchoalveolar lavage fluid for diagnosing pulmonary cryptococcosis in HIV-negative patients.
Oshima K, Takazono T, Saijo T, et al 

Med Mycol
. 2017 Apr 1
7.
Abstract

FULL-TEXT ARTICLE
Establishing a cost-per-result of laboratory-based, reflex Cryptococcal antigenaemia screening (CrAg) in HIV+ patients with CD4 counts less than 100 cells/μl using a Lateral Flow Assay (FA) at a typical busy CD4 laboratory in South Africa
Cassim N, Schnippel K, Coetzee LM, Glencross DK.
PLoS One. 2017 Feb 6;12(2):e0171675.
Paper

Identification of Disseminated Cryptococcosis Using MALDI-TOF MS and Clinical Evaluation.
Tarumoto N, Sakai J, Kodana M, et al

Med Mycol J
. 2016;57(3):E41-6.
Abstract

FULL-TEXT ARTICLE
Identification of Multiple Cryptococcal Fungicidal Drug Targets by Combined Gene Dosing and Drug Affinity Responsive Target Stability Screening.
Park YD, Sun W, Salas A,  et al
MBio. 2016 Aug 2;7(4).
Paper

Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV Related Cryptococcosis.
Jitmuang A, Panackal AA, Williamson PR, et al

J Clin Microbiol
. 2015 Nov 25
Abstract

Spectrum of imaging appearances of intracranial cryptococcal infection in HIV/AIDS patients in the anti-retroviral therapy era.
Offiah CE, Naseer A.

Clin Radiol
. 2015 Nov 9.
Abstract

Validation and clinical application of a molecular method for the identification of Cryptococcus neoformans/Cryptococcus gattii complex DNA in human clinical specimens.
Rivera V, Gaviria M, Muńoz-Cadavid C,
Braz J Infect Dis. 2015 Sep 19
Abstract

Evaluation of Fingerstick Cryptococcal Antigen Lateral Flow Assay in HIV-Infected Persons: a Diagnostic Accuracy Study.
Williams D, Kiiza T, Kwizera R,  et al

Clin Infect Dis
. 2015 Apr 1. pii: civ263
Abstract

Neuroimaging of HIV-associated cryptococcal meningitis: comparison of magnetic resonance imaging findings in patients with and without immune reconstitution.
Katchanov J, Branding G, Jefferys L,  et al
Int J STD AIDS. 2015 Feb 18.
Abstract

Latex agglutination: Diagnose the early cryptococcus neoformans test of capsular polysaccharide antigen.
Wang H, Yuan X, Zhang L.
Pak J Pharm Sci. 2015 Jan;28(1 Suppl):307-11.
Abstract

Enzyme Immunoassay versus Latex Agglutination Cryptococcal Antigen Assays in Adults With non-HIV-related Cryptococcosis.
Panackal AA, Dekker JP, Proschan M, et al

J Clin Microbiol
. 2014 Sep 24
Abstract

Rapid diagnosis of cryptococcal meningitis using the lateral flow assay on CSF samples: the influence of the high dose "hook" effect.
Lourens A, Jarvis JN, Meintjes G, Samuel CM.

J Clin Microbiol
. 2014 Sep 17. pii
Abstract

Differentiation of histoplasma and crypococcus in cytology smears: a diagnostic dilemma in severely necrotic cases.
Ranjan R, Jain D, Singh L,  et al
Cytopathology. 2014 Aug 13
Abstract

FULL-TEXT ARTICLE
Performance of cryptococcal antigen lateral flow assay using saliva in Ugandans with CD4 <100.
Kwizera R, Nguna J, Kiragga A, et al
PLoS One. 2014 Jul 31;9(7):e103156
Paper

FULL-TEXT ARTICLE
Identification of the Major Molecular Types of Cryptococcus neoformans and C. gattii by Hyperbranched Rolling Circle Amplification.
Trilles L, Wang B, Firacative C, Lazéra Mdos S,  et al

PLoS One
. 2014 Apr 15;9(4):e94648
Paper

A High-Throughput Screening Assay for Fungicidal Compounds against Cryptococcus neoformans.
Rabjohns JL, Park YD, Dehdashti J, et al
J Biomol Screen. 2014 Feb;19(2):270-7.
Abstract

FULL-TEXT ARTICLE
Multisite validation of cryptococcal antigen lateral flow assay and quantification by laser thermal contrast.
Boulware DR, Rolfes MA, Rajasingham R,  et al
Emerg Infect Dis. 2014 Jan;20(1):45-53.
Paper

Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay.
Dhana A.
Case Rep Med. 2013;2013:640216.

Abstract

A High-Throughput Screening Assay for Fungicidal Compounds against Cryptococcus neoformans.
Rabjohns JL, Park YD, Dehdashti J,  et al
J Biomol Screen
. 2013 Jul 29
Abstract

Evaluation of a rapid lateral flow immunoassay for the detection of cryptococcal antigen for the early diagnosis of cryptococcosis in HIV patients in Colombia.
Escandón P, Lizarazo J, Agudelo CI,  et al
Med Mycol
. 2013 Apr 23
Abstract

Significance of antibody detection in the diagnosis of cryptococcal meningitis.
Patil SA, Katyayani S, Arvind N.
J Immunoassay Immunochem. 2012 Apr;33(2):140-8.
Abstract

Cryptococcal lymphadenitis in HIV: A chance diagnosis by FNAC.
Bhuyan P, Pattnaik K, Kar A,  et al

Diagn Cytopathol
. 2012 Apr 17.
Abstract

Detection of Antibody against Fungal Glucosylceramide in Immunocompromised Patients:
A Potential New Diagnostic Approach for Cryptococcosis.

Qureshi A, Wray D, Rhome R,  et al

Mycopathologia
. 2011 Oct 5
Abstract

Rapid Identification of Cryptococcus neoformans var. grubii, C. neoformans var. neoformans,
and C. gattii Using Rapid Biochemical Tests, Differential Media, and DNA Sequencing.
McTaggart L, Richardson SE, Seah C,  et al
J
Clin Microbiol
. 2
011 May 18
Abstract

Assessing the Chronic Neuropsychologic Sequelae of Human Immunodeficiency
Virus-Negative Cryptococcal Meningitis by Using Diffusion Tensor Imaging.
Lu CH, Chen HL, Chang WN, et al

AJNR Am J Neuroradiol
. 2011 May 19.
Abstract

The role of serum cryptococcal antigen screening for the early diagnosis of cryptococcosis in
HIV-infected patients with different ranges of CD4 cell counts.
Pongsai P, Atamasirikul K, Sungkanuparph S.

J Infect
. 2010 Jun;60(6):474-7.
Abstract


Clinical Management
 

     Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
Cryptococcal meningoencephalitis in HIV/AIDS: when to start antiretroviral therapy?
Franco-Paredes C, Chastain DB, Rodriguez-Morales AJ, Marcos LA .
Ann Clin Microbiol Antimicrob. 2017 Mar 6;16(1):9.
Paper

FULL-TEXT ARTICLE
Integrated therapy for HIV and cryptococcosis.
Srichatrapimuk S, Sungkanuparph S.
 AIDS Res Ther. 2016 Nov 29;13(1):42.
Paper

Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment.
Gullo FP, Rossi SA, Sardi Jde C, sf al
Eur J Clin Microbiol Infect Dis
. 2013 Nov;32(11):1377-91.

Abstract

Clinical Practice Guidelines for the Management of Cryptococcal Disease:
2010 Update by the Infectious Diseases Society of America.
Perfect JR, Dismukes WE, Dromer F, et al
Clin Infect Dis. 2010 Jan 4.
Abstract

Treatment of cryptococcosis in the setting of HIV coinfection.
Khawcharoenporn T, Apisarnthanarak A, Mundy LM.
 
Expert Rev Anti Infect Ther.
2007 Dec;5(6):1019-30.
Abstract
 

FULL-TEXT ARTICLE
Determinants of Disease Presentation and Outcome during Cryptococcosis:
The CryptoA/D Study.
Dromer F, Mathoulin-Pelissier S, Launay O, et al
PLoS Med. 2007 Feb 6;4(2):e21
Paper
 

Transplant Studiers
       

     Journal Papers, Abstracts, and Commentaries

 
Cryptococcosis in solid organ transplant recipients.
Henao-Martínez AF, Beckham JD.

Curr Opin Infect Dis
. 2015 Aug;28(4):300-7
Abstract

Cryptococcosis in organ transplantation.
Islam S, Das A, Islam N.
 
Mymensingh Med J
. 2010 Jan;19(1):142-3.
Abstract

Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal
neuroimaging findings.

Singh N, Lortholary O, Dromer F, et al
Transplantation. 2008 Sep 15;86(5):647-51
Abstract
 

Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum
cryptococcal antigen.

Singh N, Alexander BD, Lortholary O, et al
Clin Infect Dis. 2008 Jan 15;46(2)
Abstract
 


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