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Last Update:  January 31, 2018
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New and Noteworthy

January 2018

General Reports

        Journal Papers, Abstracts, and Commentaries


Histoplasmosis: An oral malignancy-like clinical picture.
Chroboczek T, Dufour J, Renaux A,

Med Mycol Case Rep
. 2018 Jan 17;19:45-48.

Correlation of CD4 counts with clinical and histopathological findings in disseminated histoplasmosis: a 10-year retrospective study.
Sirait SP, Bramono K, Hermanto N
Int J Dermatol
. 2017 Jul 5.

Complete blood count alterations in disseminated histoplasmosis.
Lunardi LW, Wagner R, Dos Santos CC, et al

Rev Bras Hematol Hemoter
. 2015 Jul-Aug;37(4):263-5..

HIV-Associated Histoplasmosis Early Mortality and Incidence Trends: From Neglect to Priority
Adenis A, Nacher M, Hanf M,  et al

PLoS Negl Trop Dis
. 2014 Aug 21;8(8):e3100.

Glycosylation and immunoreactivity of the Histoplasma capsulatum Cfp4 yeast-phase exoantigen
Holbrook ED, Kemski MM, Richer SM,  et al

Infect Immun. 2014 Aug 11.

Tuberculosis and Histoplasmosis among Human Immunodeficiency Virus-Infected Patients: A Comparative Study.

Adenis A, Nacher M, Hanf M,  et al  
Am J Trop Med Hyg. 2014 Jan 6

How Many Have Died from Undiagnosed Human Immunodeficiency Virus-Associated Histoplasmosis, A Treatable Disease? Time to Act.
Nacher M, Adenis A, Aznar C,  et al

Am J Trop Med Hyg
. 2013 Nov 25.

Visibility of Histoplasma within histiocytes on hematoxylin and eosin distinguishes disseminated histoplasmosis from other forms of pulmonary histoplasmosis.
Mukhopadhyay S, Doxtader EE.
Hum Pathol. 2013 Oct;44(10):2346-52


Histoplasmosis After Solid Organ Transplantation.
Assi M, Martin S, Wheat LJ,  et al
Clin Infect Dis. 2013 Sep 17

Rheumatologic manifestations of histoplasmosis: a review.
Sizemore TC.

Rheumatol Int
. 2013 Jul 9.

Adrenal hypofunction from histoplasmosis: a literature review from 1971 to 2012.
Koene RJ, Catanese J, Sarosi GA.
nfection. 2013 Jun 15.

Histoplasmosis associated with Addison's disease.
Wilhelm L, Martins N, Loreto ES.
Rev Soc Bras Med Trop. 2013 Jan;46(1):123.

Tuberculosis and Histoplasmosis Co-Infection in AIDS Patients.
Agudelo CA, Restrepo CA, Molina DA, et al

Am J Trop Med Hyg
. 2012 Nov 5.

Protein-losing enteropathy and hypogammaglobulinaemia as first manifestations
of disseminated histoplasmosis coincident with Nocardia infection.
Kok J, Chen SC, Anderson L, Berglund L,  et al

J Med Microbiol. 2010 May;59(Pt 5):610-3.

Research on HIV/Toxoplasma gondii co-infection and cytokine levels among
intravenous drug users.
Li JR, Gong RY, Li YP, et al

Parasite Immunol
. 2010 Feb;32(2):161-4.

Risk factor analysis of Histoplasma capsulatum fungemia.
Assi MA, Sandid MS, Baddour LM, et al
Med Mycol. 2009 Feb 12:1-6.

Central nervous system histoplasmosis.
Saccente M.
Curr Treat Options Neurol. 2008 May;10(3):161-7.
Histoplasmosis story from Tennessee, U.S.A. to Turkey
Turhan V.
Mikrobiyol Bul
. 2009 Apr;43(2):339-51

Histoplasmosis: a clinical and laboratory update.
Kauffman CA 

Clin Microbiol Rev.
2007 Jan;20(1):115-32.
Chest pain resulting from histoplasmosis pericarditis: a brief report and review of the
Wang JJ, Reimold SC 

Cardiol Rev. 2006 Sep-Oct;14(5):223-6.
Histoplasmosis: a review for clinicians from non-endemic areas.
Wheat LJ.
Mycoses. 2006 Jul;49(4):274-82.
Risk factors for death in acquired immunodeficiency syndrome-associated disseminated

DE Francesco Daher E, DE Sousa Barros FA, et al 
Am J Trop Med Hyg. 2006 Apr;74(4):600-3.
Histoplasmosis and penicilliosis: Comparison of clinical features, laboratory findings and outcome.
Mootsikapun P, Srikulbutr S.  
Int J Infect Dis. 2006 Jan;10(1):66-71.

Isolated central nervous system histoplasmosis in immunocompetent hosts: A series of 11 cases.
Schestatsky P, Chedid MF, Amaral OB, et al
Scand J Infect Dis. 2006;38(1):43-8.

Histoplasmosis and penicilliosis: Comparison of clinical features, laboratory findings and
Mootsikapun P, Srikulbutr S.
Int J Infect Dis. 2005 Oct 18;

Disseminated Histoplasmosis: A Comparative Study between Patients with Acquitted Immune
Deficiency Virus Syndrome and Non-Human Immunodeficiency Virus-Infected Individuals

Tobon AM, Agudelo CA, Rosero DS, et al;; 

Am J Trop Med Hyg.
2005 Sep;73(3):576-582

Recurrent exposure to Histoplasma capsulatum in modern air-conditioned buildings.
Luby JP, Southern PM Jr, Haley CE, et al 

Clin Infect Dis.
2005 Jul 15;41(2):170-6.
Histoplasmosis after treatment with anti-tumor necrosis factor-alpha therapy.
Wood KL, Hage CA, Knox KS, et al.
Am J Respir Crit Care Med
2003 May 1;167(9):1279-82

Fungal infections among returning travelers.
Panackal AA, Hajjeh RA, Cetron MS, Warnock DW.

Clin Infect Dis 2002 Nov 1;35(9):1088-95

Disseminated infection by Histoplasma capsulatum with AIDS.
Bilkenroth U, Holzhausen HJ.
Pathologe 2001 Jul;22(4):270-5

Histoplasmosis due to Histoplasma capsulatum capsulatum and HIV infection.
elGuedj M, Couppie P, Pradinaud R, et al.

Rev Med Interne
2000 May;21(5):408-15




        Journal Papers, Abstracts, and Commentaries

Laboratory diagnostics for Histoplasmosis.
Azar MM, Hage CA.

J Clin Microbiol
. 2017 Mar 8

Disseminated histoplasmosis and AIDS: a prospective and multicentre study to evaluate the performance of different diagnostic tests.
Hoffmann ER, Daboit TC, Paskulin DD, et al
Mycoses. 2016 Jul 22.

Fluorescent in situ hybridization of pre-incubated blood culture material for the rapid diagnosis of histoplasmosis.
da Silva RM Jr, da Silva Neto JR,  et al

Med Mycol
. 2015 Feb 1;53(2):160-4

Improved Diagnosis of Acute Pulmonary Histoplasmosis by Combining Antigen and Antibody Detection.
Richer SM, Smedema ML, Durkin MM, et al

Clin Infect Dis
. 2016 Jan 20

Re-evaluation of Commercial Reagents for Detection of Histoplasma capsulatum Antigen in Urine.
Theel ES, Harring JA, Dababneh AS,  et al

J Clin Microbiol
2015 Jan 28.

Differentiation of histoplasma and crypococcus in cytology smears: a diagnostic dilemma in severely necrotic cases.
Ranjan R, Jain D, Singh L,  et al
Cytopathology. 2014 Aug 13

Evaluation of commercially available reagents for the diagnosis of Histoplasmosis infection in immunocompromised patients.
Zhang X, Gibson B Jr, Daly TM.
J Clin Microbiol. 2013 Oct 2

Giemsa and Grocott in the recognition of Histoplasma capsulatum in blood smears.
Bava J, Troncoso A, Clausen CR.

Asian Pac J Trop Biomed
. 2013 May;3(5):418-20.

The use of nested Polymerase Chain Reaction (nested PCR) for the early diagnosis of Histoplasma capsulatum infection in serum and whole blood of HIV-positive patients*.
Dantas KC, Freitas RS, Moreira AP,  et al
An Bras Dermatol. 2013 Jan-Feb;88(1):141-3

Adrenal histoplasmosis: A diagnosis on fine needle aspiration cytology.
Rana C, Kumari N, Krishnani N.

Diagn Cytopathol
. 2010 Oct 14

Detection of Latin American strains of Histoplasma in a murine model by use of a
commercially available antigen test.
Allton DR, Rivard RG, Connolly PA, et al

Clin Vaccine Immunol
. 2010 May;17(5):802-6.

Histoplasmosis: cytodiagnosis and review of literature with special emphasis on differential
diagnosis on cytomorphology.

Gupta N, Arora SK, Rajwanshi A, et al 
Cytopathology. 2009 Oct 15

Improved detection of Histoplasma antigenemia following dissociation of immune complexes.
Swartzentruber S, LeMonte A, Witt J, .et al
Clin Vaccine Immunol
. 2009 Mar;16(3):320-2

Cross-reactivity of Paracoccidioides brasiliensis, Histoplasma capsulatum, and Cryptococcus species
in the commercial kit Platelia Aspergillus EIA.
Xavier MO, Pasqualotto AC, Cardoso IC, Severo LC.  

Clin Vaccine Immunol
. 2008 Nov 19.
Isolated lymphadenitis due to Histoplasma capsulatum diagnosed by fine-needle aspiration biopsy and
Tuon FF, Gomes V, Pagliari C, et al
Rev Iberoam Micol. 2008 Mar;25(1):50-1
Detection of Histoplasma capsulatum antigenuria by ultrafiltration of samples with false-negative results.
Egan L, Connolly PA, Fuller D, et al
Clin Vaccine Immunol. 2008 Apr;15(4):726-8.
Improvement in the detection of Histoplasma antigen by a quantitative enzyme immunoassay.
Connolly PA, Durkin MM, Lemonte AM
Clin Vaccine Immunol.
2007 Oct 3;
Platelia Aspergillus assay for diagnosis of disseminated histoplasmosis.
Ranque S, Pelletier R, Michel-Nguyen A, Dromer F. et al

Eur J Clin Microbiol Infect Dis. 2007 Sep 15;
Histoplasma capsulatum fungemia in patients with acquired immunodeficiency syndrome:
detection by lysis-centrifugation blood-culturing technique.
Oliveira FD, Fernandes SS, Severo CB, et al
Rev Inst Med Trop Sao Paulo. 2007 Jun;49(3):135-138
Assessment of a quantitative PCR method for clinical diagnosis of imported histoplasmosis.
Buitrago MJ, Gomez-Lopez A, Monzon A, et al
Enferm Infecc Microbiol Clin. 2007 Jan;25(1):16-22.
Improvements in diagnosis of histoplasmosis.
Wheat LJ.
Expert Opin Biol Ther. 2006 Nov;6(11):1207-21
Detection of imported histoplasmosis in serum of HIV-infected patients using a real-time
PCR-based assay.
Buitrago MJ, Berenguer J, Mellado E, et al
Eur J Clin Microbiol Infect Dis. 2006 Oct;25(10):665-8.
Diagnosis of pulmonary histoplasmosis and blastomycosis by detection of antigen in
bronchoalveolar lavage fluid using an improved second-generation enzyme-linked
Hage CA, Davis TE, Egan L, et al
Respir Med. 2006 Jun 3;
Urine polymerase chain reaction is not as sensitive as urine antigen for the diagnosis
of disseminated histoplasmosis.
Tang YW, Li H, Durkin MM, Sefers SE, et al  

Diagn Microbiol Infect Dis.
2006 Feb 6;

Imaging spectrum in disseminated histoplasmosis: Case report and brief review.
Grover S, Midha N, Gupta M, et al 

Australas Radiol. 2005 Apr;49(2):175-8.
ELISA for early diagnosis of histoplasmosis.
Guimaraes AJ, Pizzini CV, De Matos Guedes HL, et al 
J Med Microbiol. 2004 Jun;53(Pt 6):509-14.
Detection of histoplasma capsulatum DNA in lesions of chronic ocular
histoplasmosis syndrome.
Spencer WH, Chan CC, Shen de F, Rao NA.
Arch Ophthalmol. 2003 Nov;121(11):1551-5.
Current diagnosis of histoplasmosis.
Wheat L J
Trends Microbiol. 2003 Oct;11(10):488-94.
Wheat LJ, Kauffman CA.
Infect Dis Clin North Am 2003 Mar;17(1):1-19, vii

Rapid PCR-Based Diagnosis of Disseminated Histoplasmosis in an AIDS Patient.
Rickerts V, Bialek R, Tintelnot K, et al.

Eur J Clin Microbiol Infect Dis 2002 Nov;21(11):821-3

Evaluation of two nested PCR assays for detection of Histoplasma capsulatum
DNA in human tissue.
Bialek R, Feucht A, Aepinus C, et al.
J Clin Microbiol 2002 May;40(5):1644-7

Comparison of staining methods and a nested PCR assay to detect Histoplasma
capsulatum in tissue sections.
Bialek R, Ernst F, Dietz K, Najvar LK, et al.
Am J Clin Pathol 2002 Apr;117(4):597-603

Diagnosis of histoplasmosis in urine cytology: Reactive urothelial changes, a
diagnostic pitfall. Case report and literature review ofurinary tract infections.
Mukunyadzi P, Johnson M, Wyble JG, Scott M.
Diagn Cytopathol 2002 Apr;26(4):243-6

Bone marrow aspiration, biopsy, and culture in the evaluation of HIV-infected
patients for invasive mycobacteria and histoplasma infections.
Akpek G, Lee SM, Gagnon DR , et al; 

Am J Hematol
2001 Jun;67(2):100-6



         Conference Reports, Abstracts, and Posters

  Diagnostic yield of stereotactic brain biopsy in cns lesions associated with AIDS
CG Yampolsky, M Corti, H Metta, et al

HIV Systemic Studies [Links to HIV Web]
Respiratory System Histoplasmosis   Cerebral Histoplasmosis        

Treatment/Prevention Guidelines
United States      

United States

         Journal Papers, Abstracts, and Commentaries

  Treating Opportunistic Infections Among HIV-Infected Adults and Adolescents:
Recommendations from CDC, the National Institutes of Health, and the HIV
Medicine Association/Infectious Diseases Society of America
MMWR Dec 17, 2004 / Vol. 53 / No. RR--1

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