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Abacavir (Ziagen)
 
Perinatal Data

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Last Update:  April 30, 2016
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General Reports
 
      Journal Papers, Abstracts, and Commentaries
 
  The pharmacokinetics of abacavir 600 mg once daily in HIV-1-positive pregnant women.
Schalkwijk S, Colbers A, Konopnicki D,  et al
AIDS. 2016 Feb 1. 
Abstract

Effect of drug efflux transporters on placental transport of antiretroviral agent abacavir.
 Neumanova Z, Cerveny L, Greenwood SL,  et al
 Reprod Toxicol. 2015 Jul 10. pii
 Abstract

Population Pharmacokinetics of Abacavir in Pregnant Women.
Fauchet F, Treluyer JM, Préta LH, et al
 Antimicrob Agents Chemother. 2014 Jul 28.
 Abstract

Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk, in the Mma Bana Study, Botswana.
Shapiro RL, Rossi S, Ogwu A,  et al
Antivir Ther. 2012 Nov 26.
 Abstract
Clinical Pharmacology
 

Ex Vivo Studies

      Journal Papers, Abstracts, and Commentaries

  The ex vivo human placental transfer of the anti-HIV nucleoside inhibitor abacavir and the protease inhibitor amprenavir.
Bawdon RE.
Infect Dis Obstet Gynecol 1998;6(6):244-6  
Abstract

Pharmacokinetics

     Journal Papers, Abstracts, and Commentaries
 
  Impact of pregnancy on abacavir pharmacokinetics.
 Best BM, Mirochnick M, Capparelli EV, et al  
AIDS. 2006 Feb 28;20(4):553-560.
Abstract

   

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Abacavir Perinatal Data