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Atazanavir (Reyataz)
 
Pediatric Data

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General Reports
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Last updated:  December 21, 2017
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New and Noteworthy
     
December  2017
 
General Reports
       

     Journal Abstracts, Papers, and Commentaries

 
Safety of darunavir and atazanavir in HIV-infected children in Europe and Thailand.
 European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group in EuroCoord.
Antivir Ther. 2015 Nov 12.
 Abstract

Meconium Atazanavir Concentrations and Early Language Outcomes in HIV-Exposed Uninfected Infants With Prenatal Atazanavir Exposure
 Himes SK, Huo Y, Siberry GK. et al 
J Acquir Immune Defic Syndr. 2015 Jun 1;69(2):178-86.
 Abstract

 Atazanavir: In Pediatric Patients with HIV-1 infection.
 Deeks ED.
Paediatr Drugs. 2012 Jan 31.
 Abstract

Atazanavir: In Pediatric Patients with HIV-1 infection.
 Deeks ED.
Paediatr Drugs. 2012 Jan 31.
 Abstract
 

     Conference Reports, Abstracts, and Posters

  Equivalence of boosted atazanavir based regimens and currently effective HAART regimens with other PI's/NNRTI's in HIV+ children and adolescents with elevated lipid levels
J. Piatt, J. Foti, K. Bickes, et al
(XX International AIDS Conference)
 Abstract
Pharmacokinetics
 
     Journal Abstracts, Papers, and Commentaries
 
  Pharmacokinetics and Pharmacodynamics of Atazanavir in HIV-1-Infected Children Treated With Atazanavir Powder and Ritonavir: Combined Analysis of the PRINCE-1 and -2 Studies.
Sevinsky H, Zaru L, Wang R, et al
Pediatr Infect Dis J. 2017 Dec 4
 Abstract

Pharmacokinetics of Unboosted Atazanavir in Treatment-Experienced HIV-infected Children, Adolescents and Young Adults.
 Cressey TR, Hazra R, Wiznia A, et al,
 Pediatr Infect Dis J. 2016 Aug 31.
Abstract

Pharmacokinetics of Atazanavir/Ritonavir among HIV-Infected Thai Children Concomitantly Taking Tenofovir Disoproxil Fumarate.
Bunupuradah T, Techasaensiri C, Keadpudsa S, et al
Pediatr Infect Dis J. 2014 Jun 30
 Abstract

Population pharmacokinetics of atazanavir/r in HIV-1 infected children and adolescents.
Foissac F, Blanche S, Dollfus C, et al  
Br J Clin Pharmacol. 2011 Jun 8.
Abstract

Atazanavir and Atazanavir/Ritonavir Pharmacokinetics in HIV-Infected Infants, Children,
and Adolescents.
 Kiser JJ, Rutstein RM, Samson P, et al
AIDS. 2011 May 21.
 Abstract
 
Dosing
       

     Journal Abstracts, Papers, and Commentaries

 
Model-based Approach for Optimization of Atazanavir Dose Recommendations for HIV-infected Pediatric Patients.
Hong Y, Kowalski KG, Zhang J, et al
Antimicrob Agents Chemother. 2011 Sep 19.
 Abstract
Efficacy
 

     Journal Abstracts, Papers, and Commentaries

  Safety and Efficacy of Atazanavir Powder and Ritonavir in HIV-1-Infected Infants and Children Aged From 3 Months to <11 Years: the PRINCE-2 Study.
 Cotton MF, Liberty A, Torres-Escobar I,  et al
Pediatr Infect Dis J. 2017 Dec 4.
Abstract

FULL-TEXT ARTICLE
PRINCE-1: safety and efficacy of atazanavir powder and ritonavir liquid in HIV-1-infected antiretroviral-naïve and -experienced infants and children aged ≥3 months to <6 years.
Strehlau R, Donati AP, Arce PM, et al
J Int AIDS Soc. 2015 Jun 10;18(1):19467.
 Paper

Long-Term Safety and Efficacy of Atazanavir-Based Therapy in HIV-Infected Infants, Children and Adolescents: The Pediatric AIDS Clinical Trials Group Protocol 1020A.
 Rutstein RM, Samson P, Fenton T,  et al
Pediatr Infect Dis J. 2014 Sep 17.
 Abstract

Change to a Once-Daily Combination Including Boosted Atazanavir in HIV-1-Infected Children.
 Macassa E, Delaugerre C, Teglas JP, et a 
Pediatr Infect Dis J. 2006 Sep;25(9):809-814.
 Abstract
 
Adverse Events
       

     Journal Abstracts, Papers, and Commentaries

 
Acute development of Cushing syndrome in an HIV-infected child on atazanavir/ritonavir based antiretroviral therapy.
Dubrocq G, Estrada A, Kelly S, Rakhmanina N.
 Endocrinol Diabetes Metab Case Rep. 2017 Oct 28;2017
 Abstract
Treatment Guidelines
United States 
 

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