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Didanosine (Videx)
 
Journal Citations: Adverse Events

HIV/HCV
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Last Update:  January 10, 2016
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HIV/HCV
       
 
Upper Gastrointestinal Bleeding May Unmask Didanosine-Associated Portal Hepatopathy
in HIV/HCV Co-infected Patients.
Vispo E, Maida I, Barreiro P, et al 
HIV Clin Trials. 2008 Jan 1;9(6):440-444
 Abstract

Nucleoside analogues and mitochondrial toxicity.
 Fleischer R, Boxwell D, Sherman KE.
Clin Infect Dis. 2004 Apr 15;38(8):e79-80
 Abstract
 
  High rate of didanosine-related mitochondrial toxicity in HIV/HCV-coinfected patients receiving ribavirin.
 Moreno A, Quereda C, Moreno L,et al 
Antivir Ther. 2004 Feb;9(1):133-8.
Abstract
HIV
       
 

The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction.
Blas-García A, Martí-Rodrigo A, Víctor VM, et al
J Antimicrob Chemother. 2016 Jan 7
 Abstract

FULL-TEXT ARTICLE
A Case of Non-Cirrhotic Portal Hypertension Associated With Chronic Didanosine Therapy.
 Stotts M, Chisholm P, Nurutdinova D, Maddur H.
ACG Case Rep J. 2015 Jan 16;2(2):119-20.
Paper

Pancreatic insufficiency in patients with HIV infection: role of didanosine questioned.
Martin T, Scourfield A, Rockwood N,  et al
HIV Med. 2012 Sep 21
 Abstract

Didanosine Exposure and Noncirrhotic Portal Hypertension in a HIV Clinic in North America:
a Follow-up Study.
Cachay ER, Peterson MR, Goicoechea M, Mathews WC.
Br J Md Med Res. 2011;1(4):346-355.
 Abstract

The development of hepatoportal sclerosis and portal hypertension due to didanosine use
in HIV.
Schiano TD, Uriel A, Dieterich DT, Fiel MI.|
Virchows Arch. 2010 Nov 6.
Abstract

Association of Noncirrhotic Portal Hypertension in HIV-Infected Persons and
Antiretroviral Therapy with Didanosine: A Nested Case-Control Study.
 Kovari H, Ledergerber B, Peter U, et al
Clin Infect Dis. 2009 Jul 9.
Abstract

Are disulfiram-like reactions associated with abacavir-containing antiretroviral regimens in
clinical practice?
 Barber TJ, Marett B, Waldron S, et al 
AIDS. 2007 Aug 20;21(13):1823-1824.
 Abstract
 
 
Severity of the Toxicity Associated With Combinations That Include Didanosine Plus Stavudine in
HIV-Infected Experienced Patients.
 Hernandez B, Moreno S, Perez-Elias MJ, et al 
J Acquir Immune Defic Syndr. 2006 Oct 12
 Abstract
 
Antiretroviral activity of didanosine in patients with different clusters of reverse
transcriptase mutations.
 Blanco JL, Biglia A, Lazzari ED, Mallolas J, et al
AIDS. 2006 Sep 11;20(14):1891-2.
 Abstract
 
Higher Risk of Hyperglycemia in HIV-Infected Patients Treated with Didanosine Plus Tenofovir.
 Garcia-Benayas T, Rendon AL, Rodriguez-Novoa S, et al 
AIDS Res Hum Retroviruses. 2006 Apr;22(4):333-7.
 Abstract
 
A WEEK-IN-REVIEW FEATURED REPORT
FULL-TEXT PDF ARTICLE
 A prospective study of hearing changes after beginning zidovudine or didanosine in HIV-1
treatment-naive people.
 Schouten JT, Lockhart DW, Rees TS, et al;
BMC Infect Dis. 2006 Feb 20;6(1):28
Paper

A WEEK-IN-REVIEW FEATURED REPORT
Longitudinal study on mitochondrial effects of Didanosine-tenofovir combination.
 Lopez S, Negredo E, Garrabou G, et al
AIDS Res Hum Retroviruses. 2006 Jan;22(1):33-9.
 Abstract
 
Pancreatic toxic effects associated with co-administration of didanosine and tenofovir in
HIV-infected adults.
 Martinez E, Milinkovic A, De Lazzari E, et al 
Lancet. 2004 Jul 3;364(9428):65-67.
 Abstract

Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine,
or zalcitabine.
 Walker UA, Bauerle J, Laguno M, et al.  
Hepatology. 2004 Feb;39(2):311-7.
 Abstract
 
  Matched case-control study to evaluate risk factors for hyperlactataemia in HIV patients on
antiretroviral therapy.
 Datta D, Moyle G, Mandalia S, Gazzard B.
HIV Med. 2003 Oct;4(4):311-4
 Abstract
 
  Pancreatitis treated with didanosine and tenofovir disoproxil fumarate.
 Blanchard JN, Wohlfeiler M, Canas A, et al 
Clin Infect Dis. 2003 Sep 1;37(5):e57-62.
 Abstract
 
  Fatal lactic acidosis and acute renal failure after addition of tenofovir to an ntiretroviral regimen
containing Didanosine.
 Murphy MD, O'Hearn M, Chou , et al.
Clin Infect Dis 2003 Apr 15;36(8):1082-5
 Abstract
 
  New questions about an old combination--ddI + d4T.
 Proj Inf Perspect 2003 Jan;(35):13-4
 Abstract
 
  Peripheral neuropathy during stavudine-didanosine antiretroviral therapy.
Reliquet V, Mussini JM,  Chennebault JM, et al  
 HIV Med 2001 Apr;2(2):92-6
 Abstract

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