Medical Advocates

Efavirenz
(Sustiva/Strocrin)
 
Perinatal Index


Journal Citations
Conference Citations


 


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Last Update:  March 12, 2018
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Journal Papers, Abstracts, and Commentaries
       

 
A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.
Schalkwijk S, Ter Heine R, Colbers AC. et al
Clin Pharmacokinet
. 2018 Mar 8.
Abstract

Efavirenz decreases etonogestrel exposure: a pharmacokinetic evaluation of implantable contraception with antiretroviral therapy.
Chappell CA, Lamorde M, Nakalema S, et al
AIDS
. 2017 Jul 7.
Abstract

Antiretroviral therapy with efavirenz accentuates pregnancy-associated reduction of dihydroartemisinin-piperaquine exposure during malaria chemoprevention.
Kajubi R, Huang L, Jagannathan P, Chamankhah N, et al
Clin Pharmacol Ther
. 2017 Feb 10.
Abstract

Unintended pregnancies observed with combined use of the levonorgestrel contraceptive implant and efavirenz-based antiretroviral therapy: a three-arm pharmacokinetic evaluation over 48 weeks.
Scarsi KK, Darin KM, Nakalema S,
et al
Clin Infect Dis
. 2015 Dec 8.
Abstract

Pregnancy rates in HIV-positive women using contraceptives and efavirenz-based or nevirapine-based antiretroviral therapy in Kenya: a retrospective cohort study.
Patel RC, Onono M, Gandhi M,  et al
Lancet HIV
. 2015 Nov;2(11):e474-82
Abstract

Pharmacogenetics of pregnancy-induced changes in efavirenz pharmacokinetics.
Olagunju A, Bolaji O, Amara A,  et al
Clin Pharmacol Ther
. 2015 Mar;97(3):298-306.
Abstract

Pharmacogenetics of pregnancy-induced changes in efavirenz pharmacokinetics.
Olagunju A, Bolaji O, Amara A, et al
Clin Pharmacol Ther. 2014 Nov 29.
Abstract

Efficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women.
Cohan D, Natureeba P, Koss CA,  et al 
AIDS. 2015 Jan 14;29(2):183-91

Abstract

Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS
Olagunju A, Bolaji OO, Amara A, et al
J Antimicrob Chemother
. 2014 Oct 17
Abstract

Risk Factors for Preterm Birth among HIV-Infected Pregnant Ugandan Women Randomized to Lopinavir/ritonavir- or Efavirenz-based Antiretroviral Therapy.
Koss CA, Natureeba P, Plenty A,  et al
J Acquir Immune Defic Syndr
. 2014 Jul 26
Abstract

Pharmacokinetics of efavirenz and treatment of HIV-1 among pregnant women with and without tuberculosis co-infection.
Dooley KE, Denti P, Martinson N, Cohn S,  et al
J Infect Dis
. 2014 Jul 31.

Abstract

Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis.
Ford N, Mofenson L, Shubber Z,
AIDS. 2014 Mar;28 Suppl 2:S123-31.
Abstract

Pharmacokinetics of lopinavir/ritonavir and efavirenz in food insecure HIV-infected pregnant and breastfeeding women in Tororo, Uganda.
Bartelink IH, Savic RM, Mwesigwa J, et al
J Clin Pharmacol
. 2013 Aug 23.
Abstract

Bilateral oblique facial clefts and extremity anomaly in an infant after intrauterine Efavirenz exposure and review of its teratogenic risk.
Shanske AL.
AIDS. 2012 Jun 12
Abstract

Efavirenz Pharmacokinetics during the Third Trimester of Pregnancy and Postpartum.
Cressey TR, Stek A, Capparelli E, et al
J Acquir Immune Defic Syndr
. 2011 Nov 11.
Abstract

Safety of efavirenz in first-trimester of pregnancy: an updated systematic review and meta-analysis.
Ford N, Calmy A, Mofensen L.
AIDS
.
2011 Sep 13
Abstract

Efavirenz-based combination antiretroviral therapy after peripartum single-dose nevirapine.
Bolhaar MG, Karstaedt AS.
Int J STD AIDS. 2011 Jan;22(1):38-42
Abstract

Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the IeDEA West Africa and ANRS databases, Abidjan, Côte d'Ivoire.
Ekouevi DK, Coffie PA, Ouattara E,  et al
J Acquir Immune Defic Syndr
. 2010 Nov 13.
Abstract

Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohorts.
Ford N, Mofenson L, Kranzer K,  et al 
AIDS
. 2010 May 14.
Abstract

Efavirenz in Human Breast Milk, Mothers', and Newborns' Plasma.
Schneider S, Peltier A, Gras A, et al 
J Acquir Immune Defic Syndr. 2008 Aug 1;48(4):450-454
Abstract


Conference Citations
       

 

POSTER
Lopinavir and efavirenz concentrations in paired hair samples as a marker of cumulative exposure among postpartum women and breastfeeding infants in Tororo, Uganda
J. Mwesigwa, D. Cohan, A. Plenty, et al
(XIX International AIDS Conference)

Poster     Abstract

Use of a liquid chromatography/mass spectrometry (LC/MS) in vitro assay to quantify nevirapine (NVP), efavirenz (EFV) and lamivudine (3-TC) on dried blood-spot (DBS) samples: a strategy to evaluate adherence to prevention-of-mother-to-child-transmission
E.H. Kouman, A. Martin, M.R. Adler, et al
(XIX International AIDS Conference)

Abstract

Efavirenz (EFV) concentrations in pregnant women taking EFV-based antiretroviral therapy (ART) with and without rifampin-containing tuberculosis (TB) treatment: the TSHEPISO Study Team
H. McIlleron, N. Martinson, P. Denti,  et al
(XIX International AIDS Conference)
Abstract

 


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