Medical Advocates

Cenicriviroc
 
Main Page

New and Noteworthy
Journal Data

 





 


ARV Investigational  Drugs Main New/Noteworthy Home Page      

Last Update:  December 07, 2015
 Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader

New and Noteworthy
 

December 2015

Journal Abstracts , Papers, and Commentaries
 

 
A 48-week randomized Phase 2b study evaluating cenicriviroc vs. efavirenz in treatment-naïve HIV-infected adults with CCR5-tropic virus.
Thompson M, Saag M, Dejesus E, et al
AIDS
. 2015 Dec 3.
Abstract

Incompatible natures of HIV-1 envelope in resistance to the CCR5 antagonist cenicriviroc and neutralizing antibodies.
Kuwata T, Enomoto I, Baba M, Matsushita S.
Antimicrob Agents Chemother. 2015 Nov 2
Abstract

FULL-TEXT ARTICLE
Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates.
Visseaux B, Charpentier C, Collin G,
PLoS One. 2015 Aug 6;10(8):e0134904.
Paper

The dual CCR5 and CCR2 inhibitor cenicriviroc does not redistribute HIV into extracellular space: implications for plasma viral load and intracellular DNA decline.
Kramer VG, Hassounah S, Colby-Germinario SP,
J Antimicrob Chemother. 2015 Mar;70(3):750-6.
Abstract

FULL-TEXT ARTICLE
Cenicriviroc blocks HIV entry but does not lead to redistribution of HIV into extracellular space like maraviroc.
Kramer V, Hassounah S, Colby-Germinario S,
J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19531.
Paper

Fumaric acid microenvironment tablet formulation and process development for crystalline cenicriviroc mesylate, a BCS IV compound.
Menning MM, Dalziel SM.
Mol Pharm. 2013 Nov 4;10(11):4005-15.
Abstract

FULL-TEXT ARTICLE
Comparison of genotypic and phenotypic HIV type 1 tropism assay: results from the screening samples of Cenicriviroc Study 202, a randomized phase II trial in treatment-naive subjects.
Kagan RM, Johnson EP, Siaw MF,  et al
AIDS Res Hum Retroviruses. 2014 Feb;30(2):151-9.
Paper

Safety, Efficacy, and Pharmacokinetics of TBR-652, a CCR5/CCR2 Antagonist, in
HIV-1-Infected, Treatment-Experienced, CCR5 Antagonist-Naïve Subjects.
Lalezari J, Gathe J, Brinson C,  et al
J Acquir Immune Defic Synd
r
. 2011 Feb 11.
Abstract

Cenicriviroc, an orally active CCR5 antagonist for the potential treatment of HIV infection.
Klibanov OM, Williams SH, Iler CA.

Curr Opin Investig Drugs
. 2010 Aug;11(8):940-50

Abstract
 

FULL-TEXT ARTICLE
Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule
CCR5 antagonist TAK-652.

Baba M, Miyake H, Wang X,  et al
Antimicrob Agents Chemother
. 2007 Feb;51(2):707-15
Paper


ARV Investigational  Drugs Main New/Noteworthy Home Page      

Cenicriviroc