Medical Advocates

Daprivine (TM120)
 
Main Page

New and Noteworthy
Journal Data

 






 


ARV Investigational  Drugs Main New/Noteworthy Home Page      

Last Update:  December 28, 2016
 Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader

New and Noteworthy
 

December 2016
 

Journal Abstracts , Papers, and Commentaries
 

  Comparison of Dapivirine Vaginal Gel and Film Formulation Pharmacokinetics and Pharmacodynamics (FAME 02B).
Robinon JA, Marzinke MA, Bakshi RP, et al  
AIDS Res Hum Retroviruses
. 2016 Dec 13.
  Abstract

Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women.
Nel A, van Niekerk N, Kapiga S,  et al
N Engl J Med
. 2016 Dec;375(22):2133-2143.

Abstract

Pharmacokinetic Modeling of a Gel-Delivered Dapivirine Microbicide in Humans.
Halwes ME, Steinbach-Rankins JM, Frieboes HB.
Eur J Pharm Sc
i
. 2016 Aug 21
Abstract

FULL-TEXT ARTICLE
Pharmacodynamic correlations using fresh and cryopreserved tissue following use of vaginal rings containing dapivirine and/or maraviroc in a randomized, placebo controlled trial.
Dezzutti CS, Richardson-Harman N, Rohan LC, et al
Medicine (Baltimore). 2016 Jul;95(28):e4174.
Paper

FULL-TEXT ARTICLE
S
afety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial Conducted in Multiple Countries in Sub-Saharan Africa
Nel A, Bekker LG, Bukusi E, et al
PLoS On
e
. 2016 Mar 10;11(3):e0147743

Paper

Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women.
Baeten JM, Palanee-Phillips T, Brown ER, et al
N Engl J Me
d
. 2016 Feb 2
Abstract

A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of a novel dapivirine vaginal film.
Bunge KE, Dezzutti CS, Rohan LC,et al
J Acquir Immune Defic Syndr
. 2015 Nov 11
|
Abstra
ct

Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention.
Dezzutti CS, Yandura S, Wang L, et al
Pharm Res
. 2015 Jun 16.
Abstract

Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention.
Dezzutti CS, Yandura S, Wang L, et al
Pharm Res
. 2015 Jun 16.
Abstract

Protection against re in macaques by rectal specific-gel formulations of maraviroc and tenofovir.ctal SHIV transmission
D
obard CW, Taylor A, Sharma S, et al
J Infect Dis
. 2015 Jun 12
|
Abstract

FULL TEXT ARTICLE
C
haracteristics of Women Enrolled into a Randomized Clinical Trial of Dapivirine Vaginal Ring for HIV-1 Prevention.
Palanee-Phillips T, Schwartz K, Brown ER, et al
PLoS One
. 2015 Jun 10;10(6):e0128857.
Paper

A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women.
Nel A, Haazen W, Nuttall J, Romano J,  et al
AIDS
. 2014 Jun 19;28(10):1479-87.
Abstract

FULL TEXT ARTICLE
I
ncreased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir.
Akil A, Devlin B, Cost M, Rohan LC.
Mol Pharm
. 2014 May 5;11(5):1533-41
Paper

Dual quantification of dapivirine and maraviroc in cervicovaginal secretions from ophthalmic tear strips and polyester-based swabs via liquid chromatographic-tandem mass spectrometric (LC-MS/MS) analysis.
Parsons TL, Emory JF, Seserko LA,  et al
J  Pharm Biomed Anal
. 2014 Sep;98:407-16.
Abstract

Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir.
Murphy DJ, Desjardins D, Dereuddre-Bosquet N, et al
J Antimicrob Chemother. 2014 May 26.
Abstract

Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir.
Murphy DJ, Desjardins D, Dereuddre-Bosquet N, et al
J Antimicrob Chemother
. 2014 May 26.
Abstract

 


ARV Investigational  Drugs Main Page Drugs Main Page Home Page      

Dapivirine (TMC 120)