• Mutations in multiple domains of Gag drive the emergence of in vitro resistance to the phosphonate-containing HIV-1 protease inhibitor GS-8374.
  Stray KM, Callebaut C, Glass B, et al 
  J Virol. 2012 Oct 24. [
  Abstract
• FULL-TEXT ARTICLE
  In Vitro Characterization of GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease with
  Favorable Resistance Profile.
  Callebaut C, Stray K, Tsai L, et al
  Antimicrob Agents Chemother. 2011 Jan
  Paper
• FULL-TEXT ARTICLE
  GS-8374, a novel HIV protease inhibitor, does not alter glucose homeostasis in cultured adipocytes or in a
  healthy rodent model system.
  Hruz PW, Yan Q, Tsai L,  et al
  Antimicrob Agents Chemother. 2011 Jan 18.
  Paper

GS-8374