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Last Update:  June 17, 2016
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New and Noteworthy
 

October 2014
 
 

Journal Papers, Abstracts, and Commentaries
 

 
 


Pharmacokinetics of Sifuvirtide in Treatment-Naive and Treatment-Experienced HIV-Infected Patients.
Meng Q, Dong T, Chen X, et al
J Pharm Sci
. 2014 Oct 7
Abstract

The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance.
Chong H, Yao X, Qiu Z, et al
J Antimicrob Chemothe
r
. 2014 Oct;69(10):2759-69

Abstract

FULL-TEXT ARTICLE
Efficacy, Stability, and Biosafety of Sifuvirtide Gel as a Microbicide Candidate against HIV-1.
Li L, Ben Y, Yuan S, et al
PLoS One. 2012;7(5):e37381.
Paper

FULL-TEXT ARTICLE
In vitro selection and characterization of HIV-1 variants with increased resistance to sifuvirtide,
a novel HIV-1 fusion inhibitor.
Liu Z, Shan M, Li L,
J Biol Chem. 2011 Feb 4;286(5):3277-87
Paper


Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor Sifuvirtide.
Yao X, Chong H, Zhang C
J Biol Chem
. 2012 Jan 6.

Abstract

In vitro selection and characterization of HIV-1 variants with increased resistance to sifuvirtide,
novel HIV-1 fusion inhibitor.
Liu Z, Shan M, Li L, et al
J Biol Chem
. 2011 Feb 4;286(5):3277-87.

Abstract

The role of blood cell membrane lipids on the mode of action of HIV-1 fusion inhibitor sifuvirtide.
Matos PM, Freitas T, Castanho MA, Santos NC.
Biochem Biophys Res Commun
. 2010 Nov 12
Abstract
 
An improved on-line solid phase extraction coupled HPLC-MS/MS system for quantification of sifuvirtide in human plasma.
Wang QQ, Xiang SS, Jia YB. et al

J Chromatogr B Analyt Technol Biomed Life Sci
. 2010 Jul 1;878(21):1893-8
Abstract
 
Unravelling the molecular basis of the selectivity of the HIV-1 fusion inhibitor sifuvirtide towards phosphatidylcholine-rich rigid membranes.
Franquelim HG, Veiga AS, Weissmüller G,  et al

Biochim Biophys Acta
. 2010 Jun;1798(6):1234-43
Abstract

Quantitative analysis of a novel HIV fusion inhibitor (sifuvirtide) in HIV infected human
plasma using high-performance liquid chromatography-electrospray ionization tandem
mass spectrometry.
Che J, Meng Q, Chen Z, et al
J Pharm Biomed Anal
. 2009 Oct 30.
Abstract

Sifuvirtide, a potent HIV fusion inhibitor peptide.
Wang RR, Yang LM, Wang YH, et al
Biochem Biophys Res Commun. 2009 Mar 13
Abstract

Synergistic efficacy of combination of enfuvirtide and sifuvirtide, the first- and next-generation
HIV-fusion inhibitors.
Pan C, Lu H, Qi Z, Jiang S.
AIDS
. 2009 Feb 24
 

Design and evaluation of sifuvirtide: a novel HIV-1 fusion inhibitor.
He Y, Xiao Y, Song H, et al 
J Biol Chem
. 2008 Feb 26

Abstract

 


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