Medical Advocates
Nevirapine (Viramune)
 
Journal Citations: Drug/Drug Interactions

NVP/Artemether/Lumefantrine            NVP/Rifampicin
NVP/Atazanavir                                   NVP/Tenofovir
NVP/Bedaquiline
NVP/Darunavir
NVP/Dolutegravir
NVP/Ethinyl Estradiol/Norethindrone
 NVP/Fosamprenavir
NVP/Lopinavir
NVP/Methadone
NVP/Morphine
NVP/Paclitaxel
 NVP/Piperine
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NVP/Artemether/Lumefantrine
 
  Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults.
Byakika-Kibwika P, Lamorde M, Mayito J,  et al
J Antimicrob Chemother. 2012 Jun 11.
Abstract		  
NVP/Atazanavir
 
 
Effect of nevirapine on the steady-state trough concentrations of atazanavir in
HIV-infected patients receiving atazanavir/ritonavir.
 Moltó J, Deig E, Valle M,  et al 
Ther Drug Monit. 2010 Feb;32(1):93-6.
 Abstract

Effect of Nevirapine on the Steady-State Trough Concentrations
of Atazanavir in HIV-Infected Patients Receiving Atazanavir/Ritonavir.
Moltó J, Deig E, Valle M, et al
Ther Drug Monit. 2009 Dec 19.
 Abstract

  
NVP/Bedaquiline
 
  Drug-drug interactions between bedaquiline and the antiretrovirals lopinavir/ritonavir and nevirapine in HIV-infected patients with drug-resistant TB.
 Pandie M, Wiesner L, McIlleron H, et al
J Antimicrob Chemother. 2016 Jan 7.
Abstract		  
NVP/Darunavir
 
  Pharmacokinetic interaction between nevirapine and darunavir with low-dose ritonavir in
HIV-1-infected patients.
Sekar V, Lefebvre E, Mariën K, et al
 Br J Clin Pharmacol. 2009 Jul;68(1):116-9.
 Abstract		  
NVP/Dolutegravir
 
  Influence of nevirapine administration on the pharmacokinetics of dolutegravir in patients infected with HIV-1.
 Dailly E, Allavena C, Grégoire M,  et al
J Antimicrob Chemother. 2015 Aug 13.
 Abstract		  
NVP/Ethinyl Estradiol/Norethindrone
 
  Pharmacokinetic interaction between nevirapine and ethinyl estradiol/norethindrone
when administered concurrently to HIV-infected women.
 Mildvan D, Yarrish R, Marshak A, et al.
J Acquir Immune Defic Syndr 2002 Apr 15;29(5):471-7
 Abstract		  
NVP/Fosamprenavir
 
  Interaction between Fosamprenavir, with and without Ritonavir, and Nevirapine in Human
Immunodeficiency Virus-Infected Subjects.
Dejesus E, Piliero PJ, Summers K, et al
Antimicrob Agents Chemother. 2006 Sep;50(9):3157-9
 Abstract		  

NVP/Lopinavir
 
  A population approach to study the influence of nevirapine administration on lopinavir
pharmacokinetics in HIV-1 infected patients.
 Dailly E, Reliquet V, Raffi F, Jolliet P. et al
Eur J Clin Pharmacol. 2005 Mar 11;
 Abstract
NVP/Methadone
 
 
Pharmacokinetics of methadone in human-immunodeficiency-virus-infected patients receiving
nevirapine once daily.
 Arroyo E, Valenzuela B, Portilla J, et al 
Eur J Clin Pharmacol. 2007 May 1;
Abstract

Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of
nevirapine to treat injection drug users.
Clarke SM, Mulcahy FM, Tjia J, et al 
Clin Infect Dis 2001 Nov 1;33(9):1595-7
Abstract

Nevirapine induces abstinence symptoms in patients on a methadone maintenance
program with HIV infection.
Bano Rodrigo MD, Agujetas Rodriguez M, et al.
Rev Clin Esp 2000 Jan;200(1):12-4
Abstract

 Nevirapine induced opiate withdrawal among injection drug users with HIV infection
receiving methadone.
 Altice FL, Friedland GH, Cooney EL.
AIDS 1999 May 28;13(8):957-62
 Abstract

 Methadone withdrawal when starting an antiretroviral regimen including nevirapine.
 Heelon MW, Meade LB.
Pharmacotherapy 1999 Apr;19(4):471-2
Abstract

  
NVP/Morphine
 
  No pharmacokinetic drug-drug interaction between nevirapine and paclitaxel.
 Kappelhoff BS, Huitema AD, Mairuhu AT, et al
Anticancer Drugs. 2005 Jul;16(6):627-63
 Abstract
NVP/Paclitaxel
 
  No pharmacokinetic drug-drug interaction between nevirapine and paclitaxel.
 Kappelhoff BS, Huitema AD, Mairuhu AT, et al
Anticancer Drugs. 2005 Jul;16(6):627-63
 Abstract
NVP/Piperine
 
  Influence of Piperine on the Pharmacokinetics of Nevirapine under Fasting Conditions :
A Randomised, Crossover, Placebo-Controlled Study.
 Kasibhatta R, Naidu MU. 
Drugs R D. 2007;8(6):383-391.
 Abstract
NVP/Rifampicin
 
  Pharmacokinetic Interaction Between Nevirapine and Rifampicin in HIV-Infected 
Patients With Tuberculosis.
Ribera E, Pou L, M A Lopez R, et al.
 J Acquir Immune Defic Syndr 2001 Dec 15;28(5):450-453
Abstract		  
NVP/Tenofovir
 
  Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation.
Liptrott NJ, Curley P, Moss D,  et al
J Antimicrob Chemother. 2013 Jun 21.
 Abstract

Assessment of Drug-Drug Interactions Between Tenofovir Disoproxil Fumarate and the
Nonnucleoside Reverse Transcriptase Inhibitors Nevirapine and Efavirenz in HIV-Infected Patients.
 Droste JA, Kearney BP, Hekster YA, Burger DM.
J Acquir Immune Defic Syndr. 2006 Jan 1;41(1):37-43.
 Abstract

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Drug/Drug Interactions