Medical Advocates

Nevirapine
(Viramune)
 
Journal Citations:
Switching Therapies

General Reports            
           

Switching from PIs to NNRTIs
Switching from Efavirenz to Nevirapine





 

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Last Update:  April 13, 2017
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General Reports
           

 

FULL-TEXT ARTICLE
Efficacy and safety of switching from nevirapine immediate-release twice daily to nevirapine extended-release once daily in virologically suppressed HIV-infected patients: a retrospective cohort study in Taiwan.
Lee CY, Chang HM, Kunin CM, et al
BMC Infect Dis
. 2017 Apr 11;17(1):261
Paper

Switching to nevirapine-based regimens after undetectable viral load is not associated with increased risk of discontinuation due to toxicity.
Patterson P, Socías E, Pryluka D,  et al
J Int AIDS Soc
. 2014 Nov 2;17(4(Suppl 3)):19794
Abstract


'
TRANxITION 144-week results: switching virologically stable HIV patients from immediate-release nevirapine (NVP IR) to extended-release NVP (XR).
Arastéh K, Drulak M, Guo J
J Int AIDS Soc
. 2012 Nov 11;15(6):1834
Abstract

Twenty-four-week efficacy and safety of switching virologically suppressed HIV-1-infected patients from nevirapine immediate release 200 mg twice daily to nevirapine extended release 400 mg once daily (TRANxITION).
Arasteh K, Ward D, Plettenberg A, et al 
HIV Med
.
2011 Dec 4.
Abstract

Evaluation of nevirapine-switch strategies for HIV treatment.
Gil P, de Górgolas M, Estrada V, Arranz A
HIV Med
. 2006 Nov;7(8):537-543.
Abstract


Switching from PIs to NNRTIs
           

 
Comparative effectiveness of continuing a virologically effective first-line boosted protease inhibitor combination
or of switching to a three-drug regimen containing either efavirenz, nevirapine or abacavir.
Bommenel T, Launay O, Meynard JL, et al
J Antimicrob Chemother
. 2011 Jun 1
Abstract

Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens:
a meta-analysis of randomized controlled trials.
Ena J, Leach A, Nguyen P, et al 
HIV Med.
2008 Jul 21.

Abstract
 

Comparative biological and clinical outcomes after a switch from a virologically unsuccessful
first protease inhibitor-containing antiretroviral combination to a 3-drug regimen containing
efavirenz, nevirapine, or abacavir.

Abgrall S, Yeni PG, Bouchaud O, et al
Clin Infect Dis
. 2007 Jan 1;44(1):120-7.
Abstract
 
A randomized controlled trial investigating the efficacy and safety of switching from
a protease inhibitor to nevirapine in patients with undetectable viral load.
Arranz Caso JA, Lopez JC, 
HIV Med. 2005 Sep;6(5):353-9.
Abstract
 
Substitution of nevirapine or efavirenz for protease inhibitor versus lipid-lowering therapy
for the management of dyslipidaemia.
Calza L, Manfredi R, Colangeli V, et al 
AIDS. 2005 Jul 1;19(10):1051-8. R
Abstract
 
Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz
or nevirapine.
Fisac C, Fumero E, Crespo M, et al
AIDS.
2005 Jun 10;19(9):917-925
Abstract
 
Serum adiponectin and metabolic parameters in HIV-1-infected patients after
substitution of nevirapine for protease inhibitors.
Petit JM, Duong M, Masson D, et al
Eur J Clin Invest.
2004 Aug;34(8):569-75
Abstract
 
Substitution of Nevirapine, Efavirenz, or Abacavir for Protease Inhibitors in Patients
with Human Immunodeficiency Virus Infection.
Martinez E, Arnaiz JA, Podzamczer D, et al.

N Engl J Med.
2003 Sep 11;349(11):1036-1046.
Abstract
An Interview  with José M. Gatell, MD, PhD, on the NEFA trial data reported in the
September 11 2003, New England Journal of Medicine
]

Virological, immunological, and clinical impact of switching from protease inhibitors to
nevirapine or to efavirenz in patients with human immunodeficiency virus infection and
long-lasting viral suppression
.
Negredo E, Cruz L, Paredes R, Ruiz Let al.
Clin Infect Dis 2002 Feb 15;34(4):504-10

Abstract

 

 

Switching from Efavirenz to Nevirapine
           

 
Switch from efavirenz to nevirapine, with full dose after one week: efficacy, safety and pharmacokinetics.
Curran A, Crespo M, van den Eynde E, et al
J Int AIDS Soc
. 2012 Nov 11;15(6):18346.
Abstract

Nevirapine vs efavirenz in virologically suppressed patients: differences in lipoprotein subclasses and inflammatory biomarkers.
Estrada V, Gómez-Garre M, Santos J, et al
J Int AIDS Soc. 2012 Nov 11;15(6):18151
Abstract

Is it safe to switch between efavirenz and nevirapine in the event of toxicity?
Mehta U, Maartens G.
Lancet Infect Dis.
2007 Nov;7(11):733-8.
Abstract
 

Efavirenz to Nevirapine Switch in HIV-1-Infected Patients with Dyslipidemia: A Randomized,
Controlled Study.

Parienti JJ, Massari V, Rey D, et al 
Clin Infect Dis. 2007 Jul 15;45(2):263-6.
Abstract

Switch from efavirenz to nevirapine associated with resolution of efavirenz-related
neuropsychiatric adverse events and improvement in lipid profiles.

Ward DJ, Curtin JM.
AIDS Patient Care
STDS. 2006 Aug;20(8):542-8.

Abstract

 


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