Medical Advocates

Ribavirin
 
HCV Indications

New and Noteworthy
General Reports
Adverse Events
Drug Alerts
Dosage
Monitoring
Monotherapy
Combination Therap
ies


 


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Last Update:  February 12, 2015
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New and Noteworthy
     

March 2005
 

General Reports
               

     Journal Papers, Abstracts, and Commentaries
 
  How does ribavirin improve interferon-alpha response rates in hepatitis C virus infection?
Pawlotsky M.    
J Hepatol.
2005 Jun;42(6):951-3
.
Abstract

Dosage Studies
               

     Journal Papers, Abstracts, and Commentaries
 
  Dosage adjustment of ribavirin based on renal function in Japanese patients with
chronic hepatitis C.
Maeda Y, Kiribayashi Y, Moriya T, et al 
Ther Drug Mon
it. 2004 Feb;26(1):9-15

Abstract

 
Dosage of Ribavirin in Patients With Hepatitis C Should Be Based on Renal Function: A
Population Pharmacokinetic Analysis
.

Bruchfeld A, Lindahl K, Schvarcz R, Stahle L.
Ther Drug Monit
2002Dec;24(6):701-708

Abstract

Monitoring
               

     Journal Papers, Abstracts, and Commentaries

  Ribavirin quantification in combination treatment of chronic hepatitis C.
Larrat S, Stanke-Labesque F, Plages A, et al
Antimicrob Agents Chemother 2003 Jan;47(1):124-9

Abstract

Adverse Events
               

     Journal Papers, Abstracts, and Commentaries
 
  Factors contributing to ribavirin-induced anemia.
Nomura H, Tanimoto H, Kajiwara E, et al 
J Gastroenterol Hepatol. 2004 Nov;19(11):1312-7
Abstract

Drug Alerts
               

    Internet Document
 
  FDA DRUG ALERT
Pulmonary: sarcoidosis or the exacerbation of sarcoidosis has been reported with
REBETOL (ribavirin) Capsules & Intron A (interferon alfa 2b) and should not be used
in patients with creatinine cleara
nce
March 27, 2003
News Release
 

Monotherapy
               

     Journal Papers, Abstracts, and Commentaries
 
  Efficacy of ribavirin monotherapy following combination therapy with interferon alfa-2b
and ribavirin for patients with chronic hepatitis C.
Nagayama R, Tanaka A, Ankoh H,et al 
Hepatol Res.
2005 May 2;

Abstract

Combination Therapies
               

     Journal Abstracts, Posters, and Commentaries
 
 
Effects of ribavirin combined with interferon-alpha2b on viral kinetics during first 12 weeks
of treatment in patients with hepatitis C virus genotype 1 and high baseline viral loads.
Enomoto M, Nishiguchi S, Kohmoto M, et al 
J Viral Hepat.
2004 Sep;11(5):448-54.
Abstract

FULL-TEXT PDF ARTICLE
Retreatment of hepatitis C non-responsive to Interferon. A placebo controlled randomized trial of
Ribavirin monotherapy versus combination therapy with Ribavirin and Interferon in 121 patients
in the Benelux [ISRCTN53821378].
Veldt BJ, Brouwer JT, Adler M, et al 
BMC Gastroenterol.2003 Aug 29
Paper
 

  A pilot study of eicosapentaenoic acid therapy for ribavirin-related anemia in patients with
chronic hepatitis C.

Ide T, Okamura T, Kumashiro R, et al.|
Int J Mol Med 2003 Jun;11(6):729-32
Abstract
 
Chronic hepatitis C patients with a post-treatment virological relapse re-treated with an induction
dose of 18 MU interferon-alpha in combination with ribavirin and amantadine: a two-arm randomized
pilot study.
eegink CJ, Sentjens RE, Beld MG,  et al
Viral Hepat 2003 May;10(3):174-82
Abstract


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