MedICAL ADVOCATES
Children
  Aspergillosis
Guidelines
General Reports
 Case Studies
 Diagnosis/Monitoring
 Treatment
 Drugs
National Challenges

Link to Aspergillosis Web

 
Pediatric OI Main Page Pediatric Main Page Home Page

Last Update:  May 29, 2017  

Prevention/Treatment Guidelines
       

     Journal Papers, Abstracts, and Commentaries     

  FULL-TEXT ARTICLE
Treating opportunistic infections among HIV-exposed and infected children:
recommendations from CDC, the National Institutes of Health, and the Infectious
Diseases Society of America.
Mofenson LM, Oleske J, Serchuck L, et al
MMWR Dec 3, 2004 / 53(RR14);1-63
 Paper		  
General Reports
       

     Journal Papers, Abstracts, and Commentaries     

 
Invasive Aspergillosis in Pediatric Oncology Patients: A Rare Event With Poor Prognosis -
Case Analysis to Plan Better Targeted Prophylactic or Therapeutic Measurement.
Babor F, Schuster F, Mackenzie C,  et al
Klin Padiatr. 2012 Apr 13.
Abstract

Aspergillosis in children after liver transplantation: Single center experience.
 Teisseyre J, Kaliciński P, Markiewicz-Kijewska M, et al 
Pediatr Transplant. 2007 Dec;11(8):868-7
Abstract
 
Allergic bronchopulmonary aspergillosis in paediatric cystic fibrosis patients.
de Almeida MB, Bussamra MH, Rodrigues JC. er ak
Paediatr Respir Rev. 2006 Mar;7(1):67-72.
Abstract
 
Invasive aspergillosis in children with hematologic malignancies.
Hasan RA, Abuhammour W.
Paediatr Drugs. 2006;8(1):15-24
Abstract

Prolonged survival after invasive aspergillosis: a single-institution review of 11 cases.
Wright JA, Bradfield SM, Park JR, Hawkins DS.
J Pediatr Hematol Oncol 2003 Apr;25(4):286-91
Abstract

  
     
  Current approaches to diagnosis and treatment of fungal infections in children infected
with human immuno deficiency virus.
Muller FM, Groll AH, Walsh TJ 
Eur J Pediatr 1999 Mar;158(3):187-99
Abstract		  
Diagnosis/Monitoring
       

     Journal Papers, Abstracts, and Commentaries     

 
Biomarker-based diagnostic work-up of invasive pulmonary aspergillosis in immunocompromised paediatric patients - is Aspergillus PCR appropriate?
Buchheidt D, Reinwald M, Spiess B, et al
Mycoses. 2016 Feb;59(2):67-74.
Abstract

Beta-D-Glucan Screening for the Detection of Invasive Fungal Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.
Koltze A, Rath P, Schöning S, et alZ|
 J Clin Microbiol. 2015 Jun 3.
Abstract

Galactomannan Antigen Testing for Diagnosis of Invasive Aspergillosis in Pediatric Hematology Patients.
Fisher BT, Zaoutis TE, Park JR,  et al
J Pediatric Infect Dis Soc. 2012 Jun;1(2):103-111
Abstract

The Role of Biomarkers for Diagnosis of and Therapeutic Decisions Related to Invasive Aspergillosis in Children.
Fisher BT.
 Curr Fungal Infect Rep. 2013 Mar 1;7(1):7-14.
Abstract

Aspergillus galactomannan antigen assay and invasive aspergillosis in pediatric cancer patients and hematopoietic stem cell transplant recipients.
Choi SH, Kang ES, Eo H, et al
Pediatr Blood Cancer. 2012 Oct 5
Abstract

FULL-TEXT ARTICLE
 Diagnostic potential of nested PCR, galactomannan EIA, and Beta-D-glucan for invasive aspergillosis
in pediatric patients.
Badiee P, Alborzi A, Karimi M, et al
J Infect Dev Ctries. 2012 Apr 13;6(4):352-7.
Abstract
 
Clinical Management
       

       Journal Papers, Abstracts, and Commentaries

 
Atypical invasive aspergillosis in a neutropenic child.
 Nyman AG, Peters M, Jaffe A, Sonnappa S.
 Pediatr Pulmonol. 2008 Jul;43(7):717-20.
 Abstract
 
Allergic bronchopulmonary aspergillosis: a unique presentation in a pediatric patient.
 Huppmann MV, Monson M. 
Pediatr Radiol. 2008 May 27
 Abstract
 
Invasive aspergillosis and allogeneic hematopoietic stem cell transplantation in children:
a 15-year experience.
Crassard N, Hadden H, Pondarré C, et al  
Transpl Infect Dis. 2008 Mar 4
 Abstract
 
Drugs
       

Amphotericin B   

          Journal Papers, Abstracts, and Commentaries  

  Amphotericin B-induced partial nephrogenic diabetes insipidus in a child.
Hopp L, Bernardi J, Reeves G.
Pediatr Nephrol 2001 Jul;16(7):594-7
Abstract		  

Caspofungin

          Journal Papers, Abstracts, and Commentaries  

 
FULL TEXT ARTICLE
Safety and efficacy of a caspofungin-based combination therapy for treatment of proven or
probable aspergillosis in pediatric hematological patients.
Cesaro S, Giacchino M, Locatelli F, et al
BMC Infect Dis. 2007 Apr 18;7:28
Paper
 
Efficacy and safety of caspofungin therapy in children with invasive fungal infections.
 Merlin E, Galambrun C, Ribaud P, et al
Pediatr Infect Dis J. 2006 Dec;25(12):1186-8.
Abstract

Caspofungin therapy for Aspergillus lung infection in a boy with chronic ganulomatous
disease.
Sallmann S, Heilmann A, Heinke F, et al. 
Pediatr Infect Dis J 2003 Feb;22(2):199-200
Abstract
 
Fluconazole
 
          Journal Papers, Abstracts, and Commentaries     
 
  Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia.
Döring M, Eikemeier M, Cabanillas Stanchi KM, et al
Eur J Clin Microbiol Infect Dis. 2015 Jun;34(6):1189-200
Abstract
 
 
Itraconazole
 
          Journal Papers, Abstracts, and Commentaries     
 
  Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia.
Döring M, Eikemeier M, Cabanillas Stanchi KM, et al
Eur J Clin Microbiol Infect Dis. 2015 Jun;34(6):1189-200
Abstract

Posaconazole
 
          Journal Papers, Abstracts, and Commentaries     
 
  Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia.
Döring M, Eikemeier M, Cabanillas Stanchi KM, et al
Eur J Clin Microbiol Infect Dis. 2015 Jun;34(6):1189-200
Abstract

Voriconazole   
   
          Journal Papers, Abstracts, and Commentaries  

 

Topical voriconazole solution for cutaneous aspergillosis in a pediatric patient
after bone marrow transplant.
Klein KC, Blackwood RA.
Pediatrics. 2006 Aug;118(2):e506-8.
 Abstract
 
Resolution of Orbitocerebral Aspergillosis During Combination Treatment With
Voriconazole and Amphotericin Plus Adjunctive Cytokine Therapy.
Bethell D, Hall G, Goodman TR, Klein N, Pollard AJ. 
Pediatr Hematol Oncol. 2004 May;26(5):304-307
 Abstract
 
Voriconazole for invasive aspergillosis in oncohematological patients: a single-center
pediatric experience.
Cesaro S, Strugo L, Alaggio R,
Support Care Cancer. 2003 Sep 13
Abstract

Voriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal
infections in children.
Walsh TJ, Lutsar I, Driscoll T, et al.
Pediatr Infect Dis J 2002 Mar;21(3):240-8
Abstract

  
Case Studies/Literature Reviews
       

      Journal Papers, Abstracts, and Commentaries  

 
Nosocomial legionellosis and invasive aspergillosis in a child with T-lymphoblastic leukemia.
Furtwängler R, Schlotthauer U, Gärtner B, et al I
nt J Hyg Environ Health. 2017 May 13.
Abstract

Primary Cutaneous Aspergillosis in a Preterm Infant.
Frick MA, Boix H, Longueira FC, et  
Pediatr Infect Dis J. 2016 Mar 11.
 Abstract

The clinical presentations of pulmonary aspergillosis in children with cystic fibrosis - preliminary report.
Walicka-Serzysko K, Sands D.
Dev Period Med. 2015;19(1):66-79.
 Abstract

Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia.
Sadarangani M, Harvey M, McDonald A,  et al
J Pediatr Hematol Oncol. 2015 May 9.
Abstract

Autoinduction of voriconazole metabolism in a child with invasive pulmonary aspergillosis.
Hsu AJ, Dabb A, Arav-Boger R.
Pharmacotherapy. 2015 Apr;35(4):e20-6.
 Abstract

Aspergillus fumigatus endocarditis in a pediatric liver transplant recipient: Favorable outcome
without cardiac surgery.
Mourier O, Durand P, Lambert V, et al 
Pediatr Transplant. 2008 Apr 6
 Abstract
 
Invasive nosocomial aspergillosis associated with heart failure and complete heart block
following recovery from dengue shock syndrome.
Kohli U, Sahu J, Lodha R, et al
Pediatr Crit Care Med. 2007 Jul;8(4):389-91.
 Abstract
 
FULL TEXT PDF ARTICLE
Two children with invasive gastrointestinal aspergillosis.
Kayiran P, Urganci N, Cetinkaya F, Tanik C.
Indian Pediatr. 2007 May;44(5):375-7.
 Paper
 
Central nervous system aspergillosis in children: a systematic review of reported cases.
Dotis J, Iosifidis E, Roilides E.
Int J Infect Dis. 2007 May 15;
Abstract
 
Primary cutaneous aspergillosis in a leukemic child
Torrelo A, Hernández-Martín A, Scaglione C, et al
Actas Dermosifiliogr. 2007 May;98(4):276-8.
Abstract
 
Severe Aspergillus endophthalmitis occurring after liver transplantation in an 8-month-old
baby.
Pollack K, Naeke A, Fischer R, et al
Ophthalmologe. 2007 Apr 21;
Abstract
 
Intrathecal aspergillosis and fusiform arterial aneurysms in an immunocompromised
child: a clinico-pathological case report
Laurencikas E, Sandstedt B, Soderman M.
Childs Nerv Syst. 2006 Sep 2;
 Abstract
 
Primary intestinal aspergillosis after high-dose chemotherapy and autologous stem
cell rescue.
Lehrnbecher T, Becker M, Schwabe D, et al  
Pediatr Infect Dis J. 2006 May;25(5):465-6.
 Abstract
 
 
National Challenges
       

North America

United States

    Journal Papers, Abstracts, and Commentaries  

 
Pediatric invasive aspergillosis: a multicenter retrospective analysis of 139 contemporary cases.
 Burgos A, Zaoutis TE, Dvorak CC, et al  
Pediatrics. 2008 May;121(5):e1286-94
 Abstract

Epidemiology, Outcomes, and Costs of Invasive Aspergillosis in Immunocompromised
Children in the United States, 2000.
Zaoutis TE, Heydon K, Chu JH, et al  
Pediatrics. 2006 Mar 13;
 Abstract

Pediatric OI Main Page Pediatric Main Page Home Page

Photo by Caroline Jacoby Courtesy of M/MC Photoshare at www.jhuccp.org/mmc  and subject to copyright law.
Pediatric Internet Resource Center
Aspergillosis