MedICAL ADVOCATES
Children
  Hepatitis C Drugs

General Reports
Interferon
Peginterferon
Ribavirin






 

Pediatric HCV Pediatric Main Page Home Page

Last Update:  March 09, 2017
 Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader


General Reports
         

     Journal Papers, Abstracts, and Commentaries
 

  FULL-TEXT ARTICLE
Current treatment options and response rates in children with chronic hepatitis C.
Wirth S
World J Gastroenterol. 2012 Jan 14;18(2):99-104.
Paper

Pediatric issues in new therapies for hepatitis B and C.
Schwarz KB.

Curr Gastroenterol Rep 2003 Jun;5(3):233-9
Abstract

Drug treatment of pediatric chronic hepatitis B.
Sokal E .

Paediatr Drugs
2002;4(6):361-9
Abstract


Interferon
         

Journal Papers, Abstracts, and Commentaries

 
Single-Nucleotide Polymorphisms of IL-10 and IL-28B as Predictors of the Response of IFN Therapy in HCV Genotype 4-infected Children.
Shaker OG, Nassar YH, Nour ZA, El Raziky M.
J Pediatr Gastroenterol Nutr. 2013 Aug;57(2):155-60
Abstract

Single Nucleotide Polymorphisms of IL-10 and IL- 28B as predictors to the response of interferon therapy in HCV genotype 4 infected children.Shaker OG, Nassar YH, et al
J Pediatr Gastroenterol Nut
r
. 2013 Mar 6.
Abstract

Interferon treatment in children with chronic hepatitis C: Long-lasting remission in
 responders, and risk for disease progression in non-responders.
Bortolotti F, Iorio R, Nebbia G, et al
Dig Liver Dis. 2005 May;37(5):3
Abstract
 

Combination therapy with ribavirin and interferon in a cohort of children with hepatitis C
and haemophilia followed at a pediatric haemophilia treatment center.
Puetz J, Thrower M, Kane R, Bouhasin J.
Haemophilia. 2004 Jan;10(1):87-93.
Abstract
 
Virus genotype 1b and long-term response to interferon alpha monotherapy in children with
chronic hepatitis C.

Mozer-Lisewska I, Sluzewski W, et al
Eur J Pediatr. 2003 Nov;162(11):755-9.
Abstract
 
Interferon alpha in the treatment of chronic hepatitis C in children: a meta-analysis
Di Ciommo V, Russo P, Rava L, Caprino L.
J Viral Hepat. 2003 May;10(3):210-4
Abstract
 
Efficacy of interferon-alpha treatment in Japanese children with chronic hepatitis C.
Nakashima E, Fujisawa T, Kimura A
J Gastroenterol Hepatol. 2003 Apr;18(4):411-4.
Abstract
 
Recombinant alfa-interferon plus ribavirin therapy in children and adolescents with chronic
hepatitis C.
Wirth S, Lang T, Gehring S, Gerner P.
Hepatology. 2002 Nov;36(5):1280-4.
Abstract
 
 
Does interferon and ribavirin combination therapy increase the rate of treatment response
in children with hepatitis C?
Suoglu D OD, Elkabes B, Sokucu S, Saner G.
J Pediatr Gastroenterol Nutr. 2002 Feb;34(2):199-206.
Abstract
 
An analysis of published trials of interferon monotherapy in children with chronic hepatitis C.
Jacobson KR, Murray K, Zellos A, Schwarz KB. 

Pediatr Gastroenterol Nutr
2002 Jan;34(1):52-8

Abstract

Peginterferons
         

Peginterferon/Ribavirin

          Journal Papers, Abstracts, and Commentaries
 

 
Durability of Response in Children Treated with Pegylated Interferon alfa-2a +/- Ribavirin for Chronic Hepatitis C.
Schwarz KB, Molleston JP, Jonas MM,  et al

J Pediatr Gastroenterol Nutr
. 2015 Aug 12.
Abstract

High Response Rate to Pegylated Interferon Alpha and Ribavirin Combination Therapy in Hemophilic Children with Chronic Hepatitis C; A Case-Control Study.
Mehrnoush L, Alavian SM, Sharafi H, et al
Pediatr Hematol Oncol. 2015 Jun 18.
Abstract

The clinical effectiveness and cost-effectiveness of peginterferon alfa and ribavirin for the treatment of chronic hepatitis C in children and young people: a systematic review and economic evaluation.
Hartwell D, Cooper K, Frampton GK,  et al
Health Technol Assess
. 2014 Oct;18(65):i-xxii, 1-202
Abstract

Virologic response to treatment with Pegylated Interferon alfa-2b and Ribavirin for chronic
hepatitis C in children.
Pawlowska M, Pilarczyk M, Halota W.
Med Sci Monit
. 2010 Nov 30;16(12):CR616-621
Abstract

The Combination of Ribavirin and Peginterferon Is Superior to Peginterferon and Placebo for Children
and Adolescents Chronic Hepatitis C.
Schwarz KB, Gonzalez-Peralta RP, Murray KF, et al
Gastroenterology
. 2010 Oct 28.
Abstract

Ophthalmologic Complications in Children With Chronic Hepatitis C Treated With
Pegylated Interferon.
Narkewicz MR, Rosenthal P, Schwarz KB,  et al
J Pediatr Gastroenterol Nutr. 2010 May 25
Abstract

High sustained virologic response rates in children with chronic hepatitis C
receiving peginterferon alfa-2b plus ribavirin.
Wirth S, Ribes-Koninckx C, Calzado MA, et al
J Hepatol. 2010 Feb 4.
Abstract

Design of the PEDS-C trial: pegylated interferon +/- ribavirin for children with chronic
hepatitis C viral infection.

Murray KF, Rodrigue JR, González-Peralta RP, et al 
Clin Trials
. 2007;4(6):661-73
Abstract
 

Early virological response in children with chronic hepatitis C treated with pegylated
interferon and ribavirin.

Kowala-Piaskowska A, Słuzewski W, Figlerowicz M, Mozer-Lisewska I.
Infection. 2007 Jun;35(3):175-9
Abstract
 
Effect of interferon alfa and ribavirin treatment on hepatitis C virus RNA in
serum and peripheral blood mononuclear cells in children with chronic hepatitis C.

Majda-Stanislawska E, Bednarek M, Jozwiak B, et al
Acta Gastroenterol Belg. 2006 Apr-Jun;69(2):187-90.
Abstract

Factors influencing early virological response in children with chronic hepatitis C
treated with pegylated interferon and ribavirin.
Kowala-Piaskowska A, Sluzewski W, Figlerowicz M, et al
   
Hepatol Res
. 2005 Aug 5;
Abstract
 

Peginterferon alfa-2a
 
          Journal Papers, Abstracts, and Commentaries
 
  Pegylated interferon α/ribavirin therapy enhances bone mineral density in children with chronic genotype 4 HCV infection
Megahed A, Salem N, Fathy A, et al
World J Pediatr
. 2017 Jan 27
.
Abstract

Durability of Response in Children Treated with Pegylated Interferon alfa-2a +/- Ribavirin for Chronic Hepatitis C.
Schwarz KB, Molleston JP, Jonas MM,  et al

J Pediatr Gastroenterol Nutr
. 2015 Aug 12.
Abstract

Hepatitis C virus clearance after discontinuation of pegylated interferon alpha-2a monotherapy in a child.
Endo T, Ito K, Sugiura T, Goto K.
Case Report Med. 2012;2012:597348.
Abstract

Ophthalmologic Complications in Children With Chronic Hepatitis C Treated With
Pegylated Interferon.
Narkewicz MR, Rosenthal P, Schwarz KB,  et al

J Pediatr Gastroenterol Nutr
. 2010 May 25
Abstract


Peginterferon alfa-2b

          Journal Papers, Abstracts, and Commentaries
 

 
Safety and Efficacy of Combined Treatment with Pegylated Interferon Alpha-2b and Ribavirin for HCV Genotype 4 in Children.
El-Karaksy HM, Mogahed EA, El-Raziky MS, et al 
J Interferon Cytokine Res
. 2015 Sep 25
Abstract

Efficacy and Safety of Peginterferon-alpha2b and Ribavirin Combination Therapy in Children
With Chronic Hepatitis C Infection.

Jara P, Hierro L, de la Vega A, et al 
Pediatr Infect Dis J.
2008 Jan 2
Abstract

Peginterferon alfa-2b plus ribavirin treatment in children and adolescents with
chronic hepatitis C.

Wirth S, Pieper-Boustani H, Lang T, et al
Hepatology. 2005 May;41(5):1013-8.
Abstract


Ribavirin
         

          Journal Papers, Abstracts, and Commentaries

  Combination therapy with ribavirin and interferon in a cohort of children with hepatitis C and
haemophilia followed at a pediatric haemophilia treatment center.
Puetz J, Thrower M, Kane R, Bouhasin J.
Haemophilia. 2004 Jan;10(1):87-93.
Abstract


Pediatric HCV Pediatric Main Page Home Page

Photo by Caroline Jacoby Courtesy of M/MC Photoshare at www.jhuccp.org/mmc  and is protected by current copyright law 
Pediatric Internet Resource Center
Hepatitis C Drugs