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Last Update:  March 03, 2017 
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General Reports
           

Videos
 
Anal Cancer in HIV Positive MSMs
Robert Castro, MD

 

              Journal Papers, Abstracts, and Commentaries  
 

 

Risk factors of high-grade anal intraepithelial neoplasia recurrence in HIV-infected men who have sex with men.
Burgos J, Curran A, Landolfi S, Guelar A,  et a
AIDS. 2017 Mar 1.
Abstract

Progression From Perianal High-Grade Anal Intraepithelial Neoplasia to Anal Cancer in HIV-Positive Men Who Have Sex With Men.
Tinmouth J, Peeva V, Amare H, et al
Dis Colon Rectum. 2016 Sep;59(9):836-842.
Abstract

Health-Related Quality of Life and Sexual Functioning of HIV-Positive Men Who Have Sex With Men Who Are Treated for Anal Intraepithelial Neoplasia.
Siegenbeek van Heukelom ML, Richel O, et al

Dis Colon Rectum
. 2016 Jan;59(1):42-47.
Abstract

HPV and Anal Cancer Knowledge among HIV-Infected and Non-Infected Men Who Have Sex With Men.
Fenkl EA, Jones SG, Schochet E, Johnson P.
LGBT Health. 2015 Dec 11
Abstract

Anal Cancer Screening in Men Who Have Sex with Men in the Multicenter AIDS Cohort Study.
D'Souza G, Wentz A, Wiley D, et al

J Acquir Immune Defic Syndr
. 2015 Dec 8.
Abstract

FULL-TEXT ARTICLE
Anorectal Chlamydia trachomatis Load Is Similar in Men Who Have Sex with Men and Women Reporting Anal Sex.
van Liere GA, Dirks JA, Hoebe CJ, et al

PLoS One
. 2015 Aug 11;10(8):e0134991
Paper

Correlates of anal sex roles among Malay and Chinese MSM in Kuala Lumpur, Malaysia.
Dangerfield DT 2nd, Gravitt P, Rompalo AM, et al
Int J STD AIDS. 2015 Apr 16.
Abstract

Risk of progression to high-grade anal intraepithelial neoplasia in HIV-infected MSM.
Burgos J, Curran A, Tallada N, et al
AIDS. 2015 Mar 27;29(6):695-702
Abstract

FULL-TEXT ARTICLE
Why are we not screening for anal cancer routinely - HIV physicians¿ perspectives on anal cancer and its screening in HIV-positive men who have sex with men: a qualitative study.
Ong JJ, Temple-Smith M, Chen M,  et al
BMC Public Health. 2015 Jan 31;15(1):67

Paper

FULL-TEXT ARTICLE

A prospective cohort study characterising the role of anogenital warts in HIV acquisition among men who have sex with men: a study protocol.
Brown B, Davtyan M, Leon SR,  et al

BMJ Open
. 2014 Sep 16;4(9):e005687
Paper

Increased HIV-1 Activity in Anal High-Grade Squamous Intraepithelial Lesions Compared to Unaffected Anal Mucosa in MSM.
Pollakis G, Richel O, Vis JD,  et al
Clin Infect Dis. 2014 Mar 5
Abstract

Progression of anal high-grade squamous intraepithelial lesions to invasive anal cancer among HIV-infected men who have sex with men.
Berry JM, Jay N, Cranston RD,  et al

Int J Cancer
. 2014 Mar 1;134(5):1147-55
Abstract

Anal cytology and p16 immunostaining for screening anal intraepithelial neoplasia in HIV-positive and HIV-negative men who have sex with men: a cross-sectional study.
Arora R, Pandhi D, Mishra K,  et al

 Int J STD AIDS
. 2014 Jan 16
Abstract

FULL-TEXT ARTICLE
Risk Factors for the Presence of Anal Intraepithelial Neoplasia in HIV+ Men Who Have Sex with Men.
Richel O, De Vries HJ, Dijkgraaf MG,  et al
PLoS One. 2013 Dec 18;8(12):e84030.
Paper

Gay bowel syndrome': relic or real (and returning) phenomenon?
Cooper F, Barber T.

Curr Opin Infect Dis
. 2013 Dec 12.
Abstract

One lesion, one virus: individual components of high-grade anal intraepithelial neoplasia in HIV+ men contain a single HPV type.
Richel O, Quint KD, Lindeman J,  et al

Sex Health
. 2013 Nov;10(6):586-587.

Abstract

Progression of anal high-grade squamous intraepithelial lesions to invasive anal cancer among HIV-infected men who have sex with men.
Berry JM, Jay N, Cranston RD, et al
Int J Cancer. 2013 Aug 12.
Abstract

FULL-TEXT PDF ARTICLE
The Study of the Prevention of Anal Cancer (SPANC): design and methods of a three-year prospective cohort study.
Machalek DA, Grulich AE, Hillman RJ,, et al
BMC Public Health. 2013 Oct 9;13(1):946
Paper

Risk factors for anal HPV infection and anal precancer in HIV-infected men who have sex with men.
Schwartz LM, Castle PE, Follansbee S,  et al
J
 Infect Dis
. 2013 Aug 1

Abstract

High prevalence and incidence of high-grade anal intraepithelial neoplasia among young Thai men who have sex with men with and without HIV.
Phanuphak N, Teeratakulpisarn N, Triratanachat S,  et al
AIDS. 2013 Jul 17;27(11):1753-1762.
Abstract

The Cost-Effectiveness of Screening Men Who Have Sex With Men for Rectal Chlamydial and Gonococcal Infection to Prevent HIV Infection.
Chesson HW, Bernstein KT, Gift TL,  et al
Sex Transm Dis. 2013 May;40(5):366-71
Abstract

Comparable performance of conventional and liquid-based cytology in diagnosing anal intraepithelial neoplasia in HIV-infected and -uninfected Thai men who have sex with men.
Phanuphak N, Teeratakulpisarn N, Lim C,  et al

J Acquir Immune Defic Synd
r
. 2013 Mar 26.
Abstract

Prevention of Recurrent High-Grade Anal Neoplasia With Quadrivalent Human Papillomavirus Vaccination of Men
Who Have Sex With Men: A Nonconcurrent Cohort Study.
Swedish KA, Factor SH, Goldstone SE.
|
Clin Infect Dis
. 2012 Jan 30.
Abstract

Long-term Follow-up of Infrared Coagulator Ablation of Anal High-Grade Dysplasia in Men Who Have Sex With Men.
Goldstone RN, Goldstone AB, Russ J, Goldstone SE.

Dis Colon Rectum
. 2011 Oct;54(10):1284-92
Abstract

Clinician and Patient Recognition of Anogenital Herpes Disease in HIV Positive Men
Who Have Sex With Men.
Sandlin MI, Johnston C, Bowe D, et al
Sex Transm Dis. 2011 Sep;38(9):833-6.
Abstract

Squamous cell carcinoma of the anus-an opportunistic cancer in HIV-positive male homosexuals.
Gervaz P, Calmy A, Durmishi Y, et al
World J Gastroenterol. 2011 Jul 7;17(25):2987-91.
Abstract

HAART and Progression to High-Grade Anal Intraepithelial Neoplasia in Men Who Have Sex with Men
and Are Infected with HIV.
de Pokomandy A, Rouleau D, Ghattas G, et al 
Clin Infect Dis. 2011 Mar 1
Abstract

Perianal dermatoses among men who have sex with men: A clinical profile of 32 Indian patients.
Ghosh SK, Bandyopadhyay D, Ghosh A,
 et al
Dermatol Online J
. 2011 Jan 15;17(1):9.
Abstract

Frequency of Occult High-Grade Squamous Intraepithelial Neoplasia and Invasive
Cancer within Anal Condylomata in Men Who Have Sex with Men.
Schlecht HP, Fugelso DK, Murphy RK,  et al
 
Clin Infect Dis
. 2010 May 19.
Abstract

Anal-rectal cytology: A review.
Bean SM, Chhieng DC.
 
Diagn Cytopathol
. 2009 Nov 25.
Abstract
 

  Conference Reports, Abstracts, and Posters
 
 
 
POSTER
Rectal gonorrhoea as a lead indicator of HIV trends
M. Lim, A. Wilkinson, M. Stoove, et al
(XIX International AIDS Conference)
Poster     Abstract

Prevalence and Other Notional Studies
           

  Journal Papers, Abstracts, and Commentaries  
 
 
 
Anal intraepithelial neoplasia among HIV-positive men who have sex with men.
Mata-Marín JA, Hernández-Figueroa J, Huerta-García G,  et al
Sex Health. 2015 Sep 14.
Abstract

Exposing the gaps in awareness, knowledge and estimation of risk for anal cancer in men who have sex with men living with HIV: a cross-sectional survey in Australia.
Ong JJ, Chen M, Grulich A,  et al 

J Int AIDS Soc
. 2015 Mar 30;18(1):19895
Abstract

HIV status and viral loads among men testing positive for rectal gonorrhoea and chlamydia, Maricopa County, Arizona, USA, 2011-2013.
Taylor M, Newman D, Gonzalez J, et al
HIV Med. 2014 Sep 17.

Abstract

Survival from Anal Cancer Among Hispanics-Puerto Rico, 2000-2007.
Colon-Lopez V, Ortiz AP,  et al

J Gastrointest Cancer
. 2014 Apr 4.
Abstract

FULL-TEXT ARTICLE
The prevalence of urethral and rectal Mycoplasma genitalium among men who have sex with men in China, a cross-sectional study.
Zheng BJ, Yin YP, Han Y,  et al
BMC Public Health. 2014 Feb 21;14(1):195
Paper

Screening and risk factors for anal cancer precursors in men infected with HIV in Taiwan.
Cheng SH, Chu FY, Wang CC, Hsueh YM.
J Med Virol. 2014 Feb;86(2):193-201
Abstract

Progression of anal high-grade squamous intraepithelial lesions to invasive anal cancer among HIV-infected men who have sex with men.
Berry JM, Jay N, Cranston RD, et al

Int J Cancer
. 2013 Aug 12.

Abstract

Anal squamous intraepithelial lesions are frequent among young HIV-infected men who have sex with men followed at the Spanish AIDS Research Network Cohort (CoRIS-HPV).
González C, Torres M, Benito A,  et alInt
J Cancer. 2013 Feb 12.
Abstract

FULL-TEXT PDF ARTICLE
Anal cytological abnormalities and epidemiological correlates among men who have sex with men at risk for HIV-1 infection.
Donà MG, Benevolo M, Vocaturo A, et al
BMC Cancer. 2012 Oct 16;12(1):476.
Paper

FULL-TEXT ARTICLE
Association of Human Papillomavirus Infection and Abnormal Anal Cytology among HIV-Infected MSM in Beijing, China.
Yang Y, Li X, Zhang Z, Qian HZ, et al

PLoS One
. 2012;7(4):e35983.
Paper

Anogenital warts in Danish men who have sex with men.
Skaaby S, Kofoed K
.
Int J STD AIDS
. 2011 Apr;22(4):214-7.
Abstract

Perianal dermatoses among men who have sex with men: A clinical profile of 32 Indian patients.
Ghosh SK, Bandyopadhyay D, Ghosh A, et al

Dermatol Online
J
. 2011 Jan 15;17(1):9.
Abstract

FULL-TEXT ARTICLE
Anal HPV Infection in HIV-Positive Men Who Have Sex with Men from China.
Gao L, Zhou F, Li X,
et al
PLoS One
. 2010 Dec 6;5(12):e15256.
Paper

 

 

 
             Conference Reports, Abstracts, and Posters
 
 
POSTER
High prevalence of abnormal anal cytology among HIV-positive and HIV-negative men who have sex with men in Bangkok,
Bali and Jakarta
N. Phanuphak T.P. Merati , E. Yunihastuti , et al
(XIX International AIDS Conference)
Poster     Abstract

Human Papillomavirus Infection
           

             Journal Papers, Abstracts, and Commentaries  
 
  Incidence, duration, persistence, and factors associated with high-risk anal HPV persistence among HIV-negative men having sex with men: A multi-national study.
Nyitray AG, Carvalho da Silva RJ, Chang M,  et al
 
Clin Infect Dis
. 2016 Mar 8. pii: ciw140.
Abstract

The effect of HIV infection on anal and penile human papillomavirus incidence and clearance: a cohort study among MSM.
Mooij SH, Van Santen DK, Geskus RB, et al

AIDS
. 2015 Oct 18
Abstract

FULL-TEXT ARTICLE
The Role of Polymerase Chain Reaction of High-Risk Human Papilloma Virus in the Screening of High-Grade Squamous Intraepithelial Lesions in the Anal Mucosa of Human Immunodeficiency Virus-Positive Males Having Sex with Males.
Hidalgo-Tenorio C, Rivero-Rodriguez M, Gil-Anguita C, et al

PLoS One
. 2015 Apr 7;10(4):e0123590.
Paper

FULL-TEXT ARTICLE
Association between Free Testosterone Levels and Anal Human Papillomavirus Types 16/18 Infections in a Cohort of Men Who Have Sex with Men
Hsu HK, Brown TT, Li X,  et al

PLoS One
. 2015 Mar 20;10(3):e0119447
Paper

FULL-TEXT ARTICLE
Multiple human papillomavirus infections are highly prevalent in the anal canal of human immunodeficiency virus-positive men who have sex with men.
Méndez-Martínez R, Rivera-Martínez NE, Crabtree-Ramírez B, et al
BMC Infect Dis. 2014 Dec 16;14(1):671
Paper

FULL-TEXT ARTICLE
Prevention of anal condyloma with quadrivalent human papillomavirus vaccination of older men who have sex with men.
Swedish KA, Goldstone SE.
.
et al
PLoS One. 2014 Apr 8;9(4):e93393

Paper

One lesion, one virus: individual components of high-grade anal intraepithelial neoplasia in HIV+ men contain a single HPV type.
Richel O, Quint KD, Lindeman J,  et al

Sex Health
. 2013 Nov;10(6):586-587.

Abstract

FULL-TEXT ARTICLE
Identification of Episomal Human Papillomavirus and Other DNA Viruses in Cytological Anal Samples of HIV-Uninfected Men Who Have Sex with Men.
Donà MG, Paolini F, Benevolo M,  et al

PLoS One
. 2013 Aug 12;8(8):e72228.
Paper

Risk factors for anal HPV infection and anal precancer in HIV-infected men who have sex with men.
Schwartz LM, Castle PE, Follansbee S,  et al
J
 Infect Dis
. 2013 Aug 1
Abstract

Uptake and Predictors of Anal Cancer Screening in Men Who Have Sex With Men.
D'Souza G, Rajan SD, Bhatia R, et al  
Am J Public Health. 2013 Jul 18.

Abstract

Anal human papillomavirus infection among HIV-infected and uninfected men who have sex with men in Beijing, China.
Hu Y, Qian HZ, Sun J, et al
J Acquir Immune Defic Syndr. 2013 May 31
Abstract

HPV genotype attribution and estimation of preventable fraction of anal intraepithelial neoplasia among HIV-infected men who have sex with men.
Sahasrabuddhe VV, Castle PE, Follansbee S, et al

J Infect Dis
. 2012 Nov 16
Abstract

Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men:
 a systematic review and meta-analysis.

Machalek DA, Poynten M, Jin F, et al   
Lancet Oncol. 2012 Mar 22

Abstract

Prevention of Recurrent High-Grade Anal Neoplasia With Quadrivalent Human Papillomavirus Vaccination of Men
Who Have Sex With Men: A Nonconcurrent Cohort Study.
Swedish KA, Factor SH, Goldstone SE.
|
Clin Infect Dis
. 2012 Jan 30.
Abstract

Human papillomavirus and anorectal carcinoma knowledge in men who have sex with men.
Blackwell CW, Eden C.

J Assoc Nurses AIDS Care
. 2011 Nov;22(6):444-53
Abstract
 
Six-Month Incidence, Persistence, and Factors Associated With Persistence of Anal Human Papillomavirus in Men:
The HPV in Men Study.
Nyitray AG, Carvalho da Silva RJ,  et al  

J Infect Dis
. 2011 Sep 30.
Abstract

Genital, oral, and anal human papillomavirus infection in men who have sex with men.
Dietz CA, Nyberg CR.
J Am Osteopath Assoc. 2011 Mar;111(3 Suppl 2):S19-25.
Abstract

The fear factor: drivers and barriers to follow-up screening for human papillomavirus-related
anal cancer in men who have sex with men.
Truesdale MD, Goldstone SE.

Int J STD AIDS
. 2010 Jul;21(7):482-8.
Abstract
 

  Conference Reports, Abstracts, and Posters
 
  POSTER
What drives the number of High-Risk Human Papillomavirus types in the anal canal in HIV-positive men who have sex with men?
J. del Amo, C. González R. Geskus, et al
(XIX International AIDS Conference)
Poster     Abstract

Symptoms
           

             Journal Papers, Abstracts, and Commentaries  
 
  Getting to the bottom of anal itch - a cautionary tale.
Chan DJ, Hillman RJ, Medley G.
Int J STD AIDS. 2004 Nov;15(11):772-4
Abstract
 
              Conference Reports, Abstracts, and Posters
 
 

HPV genotype attribution of anal neoplasia in HIV-positive MSM: estimating the preventable fraction and disease misclassification
V. Sahasrabuddhe, P. Castle S. Follansbee, et al
(XIX International AIDS Conference)
Abstract


Diagnostics/Screening
           

    Journal Papers, Abstracts, and Commentaries  
 
 
 
Preliminary results of a screening program for anal cancer and its precursors for HIV-infected men who have sex with men in Vigo-Spain.
Iribarren Díaz M, Ocampo Hermida A, González-Carreró Fojón J, et al
Rev Esp Enferm Dig. 2017 Feb 23
Abstract

A prospective study of anal cancer screening in HIV positive and negative men who have sex with men; results of Analogy.
Schofield AM, Sadler L, Nelson L, et al 

AIDS
. 2016 Feb 1
Abstract

FULL-TEXT ARTICLE
Exploring anal self-examination as a means of screening for anal cancer in HIV positive men who have sex with men: a qualitative study.
Ong JJ, Temple-Smith M, Chen M,  et al

BMC Public Health
. 2014 Dec 11;14(1):1257.
Paper

FULL-TEXT ARTICLE
Regional and national guideline recommendations for digital ano-rectal examination as a means for anal cancer screening in HIV positive men who have sex with men: a systematic review.
Ong JJ, Chen M, Grulich AE, Fairley CK.
BMC Cancer. 2014 Aug 1;14(1):557.
Paper

OC-071 Screening For Anal Pre-cancer In H{V Positive And Negative Men Who Have Sex With Men (msm) And Renal Transplant Recipients: Early Experience From A Manchester Based Prospective Study.
Schofield A, McMahon R, Sukthankar A, et al
Gut. 2014 Jun;63 Suppl 1:A35-6.
Abstract

Anal cytology and p16 immunostaining for screening anal intraepithelial neoplasia in HIV-positive and HIV-negative men who have sex with men: a cross-sectional study.
Arora R, Pandhi D, Mishra K, et al

Int J STD AIDS
. 2014 Jan 16.
Abstract

The inside story. Physicians' views on digital ano-rectal examination for anal cancer screening of HIV positive men who have sex with men.
Ong J, Chen M, Temple-Smith M, et al

J Med Screen
. 2013;20(4):188-91.
Abstract

Initiation of an anal cancer screening in HIV+MSM: results of cytology, biopsy and determination of risk factors.
Libois A, Feoli F, Nkuize M,  et al
J Int AIDS Soc. 2012 Nov 11;15(6):18436.
Abstract

FULL-TEXT ARTICLE
Anal cytology screening in HIV-positive men who have sex with men: experience in a city centre HIV clinic.
Goodall L, Clutterbuck D.

Int J STD AIDS
. 2012 Sep;23(9):623-5.
Paper

HPV genotyping, HPV mRNA expression, and p16/Ki-67 cytology to detect anal cancer precursors in HIV-infected men
 who have sex with men.

Wentzensen N, Follansbee S, Borgonovo S,
AIDS. 2012 Sep 26.
Abstract

Assessing Urine Human Papillomavirus Polymerase Chain Reaction Testing As a Tool for Screening Anal HPV infection in
HIV-Positive MSM.

Lanoix JP, Pannier C, Borel A,  et al

AIDS Patient Care STDS
. 2012 Feb 9.
Abstract

The Need for Anal Dysplasia Screening and Treatment Programs for HIV-Infected Men Who Have Sex With Men:
A Review of the Literature.
Roark R.
J Assoc Nurses AIDS Care. 2011 Nov;22(6):433-43.
Abstract

Anal cytology screening in HIV-positive men who have sex with men: what's new and
what's now?

Ho KS, Cranston RD.

Curr Opin Infect Dis
. 2010 Feb;23(1):21-5.
Abstract


Clinical Management
           

             Journal Papers, Abstracts, and Commentaries  
 
 
The effectiveness of electrocautery ablation for the treatment of high-grade anal intraepithelial neoplasia in HIV-infected men who have sex with men.
Burgos J, Curran A, Landolfi S, et a
l
HIV Med
. 2015 Dec 21.
Abstract

Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
Richel O, de Vries HJ, van Noesel CJ, et al 
Lancet Oncol. 2013 Mar 14.
Abstract

Electrocautery Ablation of High-Grade Anal Squamous Intraepithelial Lesions in HIV-Negative and HIV-Positive
Men who have sex with Men.
Marks DK, Goldstone SE.
 
 JAcquir Immune Defic Syndr
. 2011 Nov 30
Abstract

Long-term Follow-up of Infrared Coagulator Ablation of Anal High-Grade Dysplasia in Men Who Have Sex With Men.
Goldstone RN, Goldstone AB, Russ J, Goldstone SE.

Dis Colon Rect
um
. 2011 Oct;54(10):1284-92.
Abstract

Clinician and Patient Recognition of Anogenital Herpes Disease in HIV Positive Men
Who Have Sex With Men.
Sandlin MI, Johnston C, Bowe D, et al

Sex Transm Dis
. 2011 Sep;38(9):833-6.
Abstract

A double-blind, randomized controlled trial of the use of imiquimod cream for the treatment of
anal canal high-grade anal intraepithelial neoplasia in HIV-positive MSM on HAART,
with long-term follow-up data including the use of open-label imiquimod.
Fox PA, Nathan M, Francis N,  et al
 
AIDS
. 2010 Aug 19.
Abstract

More than a decade on: review of the use of imiquimod in lower anogenital intraepithelial
neoplasia.

Mahto M, Nathan M, O'Mahony C.

Int J STD AIDS
. 2010 Jan;21(1):8-16.
Abstract


HAART
           

             Journal Papers, Abstracts, and Commentaries  

 
HAART slows progression to anal cancer in HIV-infected MSM.
Duncan KC, Chan KJ, Chiu CG,  et al 

AIDS
. 2015 Jan 28;29(3):305-1
Abstract
 

Prevention
           

             Journal Papers, Abstracts, and Commentaries  
 
FULL-TEXT ARTICLE
Prevention of anal condyloma with quadrivalent human papillomavirus vaccination of older men who have sex with men.
Swedish KA, Goldstone SE.
.
et al
PLoS One. 2014 Apr 8;9(4):e93393

Paper

 


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MSM Anal /Rectal Lesions/Carcinoma