Medical Advocates
HIV Infection/Disease
 
Management of Lipodystrophy-Related Disorders


General Reports
 Diagnostics
 Modification of ARV Therapy
 Drugs
Nutrition
 Surgery
Exercise
 Miscellaneous Agents
 Medication Adherence
 
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Last Update: June 24, 2017
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General Reports
       
       Journal Papers, Abstracts, and Commentaries
 
 
Clinical management of HIV-associated lipodystrophy.
Pirmohamed M.
 Curr Opin Lipidol. 2009 Jun 2.
 Abstract

Pathogenesis and treatment of lipodystrophy: what clinicians need to know.
Sattler FR.
Top HIV Med. 2008 Oct-Nov;16(4):127-33.
 Abstract
 
Approach to the human immunodeficiency virus-infected patient with lipodystrophy.
Brown TT.
J Clin Endocrinol Metab. 2008 Aug;93(8):2937-45.
 Abstract
 
HIV lipodystrophy and its metabolic consequences: implications for clinical practice.
Wierzbicki AS, Purdon SD, Hardman TC, et al
 Curr Med Res Opin. 2008 Jan 18
Abstract
 
Treatment options for lipodystrophy in HIV-positive patients.
Behrens GM. 
Expert Opin Pharmacother. 2008 Jan;9(1):39-52
 Abstract
 
Experience in the treatment of HIV-associated lipodystrophy.
Nelson L, Stewart KJ.
J Plast Reconstr Aesthet Surg. 2007 Nov 16;
 Abstract

Multidisciplinary Approach to the Treatment of Metabolic and Morphologic Alterations of
HIV-Related Lipodystrophy.
Guaraldi G, Orlando G, Squillace N, et al
HIV Clin TrialsHIV Clin Trials. 2006 May-Jun;7(3):97-106.
Abstract

Diagnostics
 
        Journal Papers, Abstracts, and Commentaries
 
 
FULL-TEXT ARTICLE
The development of simple anthropometric measures to diagnose antiretroviral therapy-associated lipodystrophy in resource limited settings.
Abrahams Z, Dave JA, Maartens G, Lesosky M, Levitt NS.
AIDS Res Ther. 2014 Aug 4;11:26.
Paper

Evaluation of glucose uptake by skeletal muscle tissue and subcutaneous fat
in HIV-infected patients with and without lipodystrophy using FDG-PET.
Sathekge M, Maes A, Kgomo M,  et al
Nucl Med Commun. 2010 Feb 6.
 Abstract

Ultrasonographic assessment of lipodystrophy in HIV-1-infected patients.
Grima PF, Chiavaroli R, Grima P.
 Radiol Med. 2008 Oct 25.
Abstract
 
MRI of intra-abdominal fat and HIV-associated lipodystrophy: a case review.
Carlier R, De Truchis P, Ronze S, et al
J Radiol. 2007 Jul-Aug;88(7-8 Pt 1):947-56.
 Abstract
 
Association between Physical and Echographic Fat Thickness Assessments and a Lipodystrophy
Grading Scale in Lipodystrophic HIV Patients: Practical Implications.
Asensi V, Martin-Roces E, Collazos J, et al;
AIDS Res Hum Retroviruses. 2006 Sep;22(9):830-6.
Abstract
 
Centralized Assessment of Dual-Energy X-ray Absorptiometry (DEXA) in Multicenter Studies
of HIV-Associated Lipodystrophy.
Smith DE, Hudson J, Martin A, et al.
HIV Clin Trials 2003 Jan-Feb;4(1):45-9
 Abstract
 
Overcoming subjectivity in assessing facial lipoatrophy: is there a role for three-dimensional
laser scans?Benn P, Ruff C, Cartledge J, et al.
HIV Med. 2003 Oct;4(4):325-331
 Abstract
 

CT appearances of HIV-related lipodystrophy syndrome.
Gellett LR, Haddon L, Maskell GF.
Br J Radiol 2001 Apr;74(880):382-3
 Abstract

     Conference Reports, Abstracts, and Posters
 
 
FDG-PET for early detection of lipodystrophy in HIV-infected patients
CP Bleeker-Rovers, B Zomer, P Koopmans
 (15IAC)
 Abstract

Modification of ARV Therapy
 

        Journal Papers, Abstracts, and Commentaries

  Comparison of Metabolic Abnormalities and Clinical Lipodystrophy 48 Weeks After
Switching from HAART to Trizivir Versus Continued HAART: The Trizal Study.
Lafeuillade A, Clumeck N, Mallolas J,
HIV Clin Trials 2003 Jan-Feb;4(1):37-43
 Abstract		  
 
Conference Reports, Abstracts, and Posters
 		    
 
Lipodystrophy in patients switched to indinavir/ritonavir 800/100mg bid and efavirenz
100mg bid and efavirenz 600mg qd after failing nucleoside combination therapy- 96
 week lipodystrophy outcomes in HIV-NAT 009
MA Boyd, D Bien, K Ruxrungtham
(15IAC)
 Abstract
 
Improvement of lipidic assestment and of lipodystrophy in HIV-experienced patients during
prolongued antiretroviral treatment interruption (PTI)
C Martinelli, R Giuntini, S Ambu, et al
 (15IAC)
 Abstract
 

Nutritional Interventions
       

       Journal Papers, Abstracts, and Commentaries

 
A Randomized Clinical Trial to Evaluate the Effect of Diet on Quality of Life and Mood of
People Living With HIV and Lipodystrophy.
Reid C, Courtney M. 
J Assoc Nurses AIDS Care. 2007 Jul-Aug;18(4):3-11
 Abstract
 

Modifiable dietary habits and their relation to metabolic abnormalities in men and
women with human immunodeficiency virus infection and fat redistribution.
 Hadigan C, Jeste S, Anderson EJ, et al.
 Clin Infect Dis 2001 Sep 1;33(5):710-7
 Abstract

 

         Conference Reports, Abstracts, and Posters

 
To document the prevalence of lipodystrophy in HIV positive patients and whether
dietary intervention can alter such effects
GW B Ng, PW Lung, MP Lee, et al
 (15IAC)
 Abstract
 		  

Surgery
       
       Journal Papers, Abstracts, and Commentaries
 
 
Gluteal Augmentation With Intramuscular Implants in Patients With Human Immunodeficiency Virus With Lipoatrophy Related to the Use of Antiretroviral Therapy.
Andrade GA, Coltro PS, Barros ME, et al    
Ann Plast Surg. 2017 Jun 9.
Abstract

The Unknown/The Unanticipated: A Surgical Journey of Correcting HIV-Related Abdominal Lipodystrophy.
Vella MM.
 Qual Health Res. 2015 Feb 10.
 Abstract

Autologous fat grafting and injectable dermal fillers for HIV associated facial lipodystrophy: A comparison of safety, efficacy and long-term treatment outcomes.
Shuck J, Iorio ML, Hung R, Davison SP
Plast Reconstr Surg. 2012 Nov 8
 Abstract

Plastic surgical options for HIV-associated lipodystrophy.
Nelson L, Stewart KJ. 
J Plast Reconstr Aesthet Surg. 2007 Dec 20
Abstract

Surgical Algorithm for Management of HIV Lipodystrophy.
Davison SP, Timpone J Jr, Hannan CM.
 Plast Reconstr Surg. 2007 Dec;120(7):1843-58
 Abstract

Exercise
       
       Journal Papers, Abstracts, and Commentaries
 
  Exercise training in HIV-1-infected individuals with dyslipidemia and lipodystrophy.
 Terry L, Sprinz E, Stein R, Medeiros NB, Oliveira J, Ribeiro JP. 
Med Sci Sports Exerc. 2006 Mar;38(3):411-7.
 Abstract

Miscellaneous Agents
       
       Journal Papers, Abstracts, and Commentaries
 
 
Growth hormone axis treatments for HIV-associated lipodystrophy: a systematic review of
placebo-controlled trials.
Sivakumar T, Mechanic O, Fehmie D, Paul B.
HIV Med. 2011 Jan 25.
 Abstract

Leptin replacement improves postprandial glycemia and insulin sensitivity in human
immunodeficiency virus-infected lipoatrophic men treated with pioglitazone: a pilot study.
Magkos F, Brennan A, Sweeney L,  et al
Metabolism. 2010 Nov 15
 Abstract

Low-dose physiological growth hormone in patients with HIV and abdominal fat accumulation:
a randomized controlled trial.
Lo J, You SM, Canavan B, et al
JAMA. 2008 Aug 6;300(5):509-19.
 Abstract
 
Prevalence of Complementary and Alternative Medicine Use Among HIV Patients for
Perceived Lipodystrophy.
Cho M, Ye X, Dobs A, Cofrancesco J.
 J Altern Complement Med. 2006 Jun;12(5):475-82.
 Abstract

Highly Purified 1000-cSt Silicone Oil for Treatment of Human Immunodeficiency
Virus-Associated Facial Lipoatrophy: An Open Pilot Trial.
Jones DH, Carruthers A, Orentreich D, et al 
Dermatol Surg. 2004 Oct;30(10):1279-86.
 Abstract

Medication Adherence
       
       Journal Papers, Abstracts, and Commentaries
 
  Lipodystrophy-Associated Symptoms and Medication Adherence in HIV/AIDS.
 Corless IB, Kirksey KM, Kemppainen J 
AIDS Patient Care STDS. 2005 Sep;19(9):577-86.
 Abstract

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Management of HIV-Associated
 Lipodystrophy-Related Disorders