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HIV Infection/Disease
  Hepatic Disorders
 
New and Noteworthy
General Reports
Cirrhosis   
Gilbert's Disease  
Hyperbilirubinemia
Hepatic Failure      
Hepatic Encephalopathy
Hepatic Toxoplasmosis
Hepatic Steatosis
Hepatic Lymphoma
Hepatocellular Carcinoma
Hepatoportal Stenosis
Fatty Liver Disease
Liver Fibrosis
ARV Hepatic Adverse Events

Liver Transplantation

HIV/HCV 
Cholangiopathy

Steatohepatitis
Liver Abscess
 

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Last Update:  January 19, 2018  
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New and Noteworthy
     

January 2018
 

General Reports
       

           Journal Papers, Abstracts, and Commentaries
 
 
 

Human Immunodeficiency Virus Infection, Antiretroviral Therapy, and Liver Pathology.
Sonderup MW, Wainwright HC.

Gastroenterol Clin North Am
. 2017 Jun;46(2):327-343
Abstract

Non-viral liver disease burden in HIV-monoinfected individuals: a longitudinal observational retrospective cohort study.
Shur NF, Tan Y, Goubet S, et aj;
AIDS Care. 2016 Dec;28(12):1522-1527
Abstract

Liver involvement in human immunodeficiency virus infection.
Puri P, Kumar S.
Indian J Gastroenterol. 2016 Jun 3
Abstract

Highly Active Antiretroviral Therapy Mitigates Liver Disease in HIV Infection.
Price JC, Seaberg EC, Phair JP, et al
J Acquir Immune Defic Syndr. 2016 Mar 3.
Abstract

HIV and Liver Disease: An Update.
Sherman KE, Rockstroh J, Thomas D.

Hepatology
. 2015 Sep 4.
Abstract

Chronic Liver Disease in the Human Immunodeficiency Virus Patient.
Acharya C, Dharel N, Sterling RK
Clin Liver Dis. 2015 Feb;19(1):1-22.
Abstract

Circulating miRNAs as marker for liver injury in HIV patients.
Anadol E, Schierwagen R, Elfimova N,  et al 
 
Hepatology
. 2014 Aug 14.
Abstract

Predictors of chronic liver disease in individuals with human immunodeficiency virus infection.
Rafiq N, Stepanova M, Lam B,  et al

Ann Hepatol
. 2013 Jan-2014 Feb;13(1):60-4
Abstract

Human immunodeficiency virus and liver disease forum 2012.
Sherman KE, Thomas D, Chung RT.
Hepatology. 2013 Jul 31.
Abstract

FULL-TEXT ARTICLE
Incidence of Liver Damage of Uncertain Origin in HIV Patients Not Co-Infected with HCV/HBV.
Rivero-Juárez A, Camacho A, Merchante N,  et al

PLoS One
. 2013 Jul 18;8(7):e68953.
Paper

The Changing Epidemiology of Liver Disease in HIV Patients.
Soriano V, Barreiro P, Sherman KE.
AIDS Rev. 2013 Feb 28;15(1):25-31.
Abstract

The Effect of HIV Infection, Immunodeficiency and Antiretroviral Therapy on the Risk of
Hepatic Dysfunction.
Towner WJ, Xu L, Leyden WA, et al

J Acquir Immune Defic Synd
r
. 2012 Feb 16
Abstract

The association of HIV viral load with indirect markers of liver injury.
Forrester JE, Rhee MS, McGovern BH, et al

J Viral Hepat
. 2012 Feb;19(2):e202-11.
Abstract

Liver disease, HIV and aging.
Falade-Nwulia O, Thio CL.

Sex Healt
h
. 2011 Nov;8(4):512-20.
Abstract

HIV Variability in the Liver and Evidence of Possible Compartmentalization.
Blackard JT, Ma G, Martin CM,  et al
AIDS Res Hum Retroviruses. 2011 Oct;27(10):1117-26.

Abstract

Influence of antiretroviral therapy on liver disease.
Kovari H, Weber R.
Curr Opin HIV AIDS. 2011 Apr 20
Abstract

Increasing burden of liver disease in patients with HIV infection.
Joshi D, O'Grady J, Dieterich D, et al
Lancet. 2011 Apr 2;377(9772):1198-209.
Abstract

Liver Disease in the HIV-Infected Individual.
Price JC, Thio CL.

Clin Gastroenterol Hepatol
. 2010 Sep 16
Abstract

An unusual pathogen for a liver abscess in a human immunodeficiency
virus-infected individual.
Sayana S, Ricaurte JC, Khanlou H.
Am J Med Sci. 2010 Mar;339(3):290-1.
Abstract

Prevalence and Factors Associated with Liver Enzyme Abnormalities among HIV-Infected.
Crum-Cianflone N, Collins G, Medina S, et al
Clin Gastroenterol Hepatol. 2009 Oct 1
Abstract

 

Cirrhosis
       

           Journal Papers, Abstracts, and Commentaries

 
Associations between lipodystrophy or antiretroviral medications and cirrhosis in patients with HIV infection or HIV/HCV coinfection.
Ioannou GN, Bryson CL, Weiss NS, Boyko EJ.

Eur J Gastroenterol Hepatol
. 2015 Mar 12.
Abstract

The prevalence of cirrhosis and hepatocellular carcinoma in patients with HIV infection.
Ioannou GN, Bryson CL, Weiss NS,  et al

Hepatology
.
2012 Apr 24.
Abstract

From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients:

diagnosis and management.
Lemoine M, Serfaty L, Capeau J.
Curr Opin Infect Dis. 2012 Feb;25(1):10-6..
Abstract

Survival of HIV-infected patients with compensated liver cirrhosis.
Tuma P, Jarrin I, Del Amo J, Vispo E,  et al

AIDS
. 2010 Feb 11.
Abstract

 

Gilbert's Disease
       


Hyperbilirubinemia
 

        Journal Papers, Abstracts, and Commentaries
 
 
Practical preclinical model for assessing the potential for unconjugated hyperbilirubinemia
produced by human immunodeficiency virus protease inhibitors.
Kempf DJ, Waring JF, Morfitt DC, et al 
Antimicrob Agents Chemother. 2006 Feb;50(2):762-4.
Abstract

Hyperbilirubinemia in the setting of antiviral therapy.
Korenblat KM, Berk PD.  
Clin Gastroenterol Hepatol.
2005 Apr;3(4):303-10
.
Abstract

 

Hepatic Failure
       

        Journal Papers, Abstracts, and Commentaries
 
 

 

Orthotopic liver transplantation in patients with human immunodeficiency virus and
end-stage liver disease.
Neff GW, Bonham A, Tzakis AG
Liver Transpl
Abstract

Hepatic Encephalopathy
       

           Journal Papers, Abstracts, and Commentaries

 
Hepatic encephalopathy as an unusual late complication of transjugular intrahepatic
portosystemic shunt insertion for non-cirrhotic portal hypertension caused by nodular
regenerative hyperplasia in an HIV-positive patient on highly active antiretroviral therapy.
Ding A, Lee A, Callender M, et al
Int J STD AIDS. 2010 Jan;21(1):71-2
Abstract
 

Hepatic Toxoplasmosis
       

         Journal Papers, Abstracts, and Commentaries
 
  Gastric toxoplasmosis in a patient with acquired immunodeficiency syndrome.
A case report and review of the literature.
Ganji M, Tan A, Maitar MI, et al.
Arch Pathol Lab Med 2003 Jun;127(6):732-4
Abstract
 

Hepatic Steatosis
       

           Journal Papers, Abstracts, and Commentaries
 
 
Hepatic steatosis progresses faster in HIV mono-infected than HIV/HCV co-infected patients and is associated with liver fibrosis.
Pembroke T, Deschenes M, Lebouché B,  et al
J Hepatol. 2017 May 17.
bstract

Sex differences in the association of HIV infection with hepatic steatosis.
Kardashian A, Ma Y, Scherzer R, et al

AIDS
. 2016 Nov 7.
Abstract

Validation of Non-invasive Methods for Detecting Hepatic Steatosis in Patients with HIV Infection.
Siddiqui MS, Patidar KR, Boyett S,  et al

Clin Gastroenterol Hepatol
. 2014 Jul 5
Abstract

Prevalence and factors associated with liver steatosis as measured by transient elastography with controlled attenuation parameter in HIV-infected patients.
Juan M, Juan G, Cristina T,  et al

AIDS
. 2014 Mar 7.
Abstract

FULL-TEXT PDF ARTICLE
Liver steatosis in Chinese HIV-infected patients with hypertriglyceridemia: characteristics and independent
risk factors.
Xiao J, Han N, Yang D, Zhao H.

Virol J
. 2013 Aug 14;10(1):261
Paper

Hepatic Steatosis in Human Immunodeficiency Virus: A Prospective Study in Patients
Without Viral Hepatitis, Diabetes, or Alcohol Abuse.
Sterling RK, Smith PG, Brunt EM.
J Clin Gastroenterol. 2012 Oct 10
Abstract

Prospective evaluation of hepatic steatosis in HIV-infected patients with or without
hepatitis C virus co-infection.
Li Vecchi V, Soresi M, Giannitrapani L, et al
Int J Infect Dis. 2012 Mar 17.
Abstract

 

Hepatoportal Sclerosis
       

         Journal Papers, Abstracts, and Commentaries
 
  Hepatoportal Sclerosis as a Cause of Noncirrhotic Portal Hypertension in Patients
With HIV.
Schiano TD, Kotler DP, Ferran
E, Fiel MI.
AIDS. 2007 Jul 31;21(12):1591-1600
Abstract
 

Hepatic Lymphoma
       

         Journal Papers, Abstracts, and Commentaries
 
  Complete remission of primary hepatic lymphoma in a patient with human immunodeficiency virus.
Widjaja D, AlShelleh M, Daniel M, Skaradinskiy Y.
World J Clin Cases
. 2015 Feb 16;3(2):186-90
Abstract
 

Hepatocellular Carcinoma
       

           Journal Papers, Abstracts, and Commentaries
 
 
Systemic Inflammatory Response Is a Prognostic Marker in HIV-Infected Patients with Hepatocellular Carcinoma.
Pinato DJ, Merli M, Dalla Pria A,
Oncology. 2017 Sep 16.
Abstract

Hepatocellular carcinoma in patients with HIV.
Dika IE, Harding JJ, Abou-Alfa GK.

Curr Opin HIV AIDS
. 2016 Oct 15.
Abstract

Incidence of Hepatocellular Carcinoma in HIV-Infected Patients With Cirrhosis: A Prospective Study.
Montes Ramírez ML, Miró JM, Quereda C,  et al

J Acquir Immune Defi
c Syndr
. 2014 Jan 1;65(1):82-6.

Abstract

Hepatocellular Carcinoma in HIV-Infected Women: Two Case Reports.
Taylor LE, Tashima KT, Cu-Uvin S,  et al
R I Med J (2013). 2013 Jan 4;96(1):21-4.
Abstract


Fatty Liver Disease
       

           Journal Papers, Abstracts, and Commentaries
 

 
Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) in HIV.
Rockstroh JK.

Curr HIV/AIDS Rep
. 2017 Mar 10.
Abstract

Impact of genetic polymorphisms associated with nonalcoholic fatty liver disease on HIV-infected individuals.
Macias J, Rivero-Juarez A, Neukam K, et al
AIDS. 2015 Sep 24;29(15):1927-1935.
Abstract

Risk Factors for Fatty Liver in the Multicenter AIDS Cohort Study.
Price JC, Seaberg EC, Latanich R, et al
Am J Gastroenterol. 2014 Mar 18.
Abstract

FULL-TEXT ARTICLE
Role of Mitochondria in HIV Infection and Associated Metabolic Disorders: Focus on Nonalcoholic Fatty Liver Disease and Lipodystrophy Syndrome.
Pérez-Matute P, Pérez-Martínez L, Blanco JR, Oteo JA.

Oxid Med Cell Longev
. 2013;2013:493413
Paper

From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients:
diagnosis and management.
Lemoine M, Serfaty L, Capeau J.
Curr Opin Infect Dis. 2012 Feb;25(1):10-6..
Abstract

Non-Alcoholic Fatty Liver Disease in HIV Infection Associated with Altered Hepatic
Fatty Acid Composition.
Arendt BM, Mohammed SS, Ma DW, et al
|
Curr HIV Res
. 2011 Mar 24
Abstract

 

Hepatocellular Carcinoma
       

           Journal Papers, Abstracts, and Commentaries

 
Hepatocellular carcinoma in HIV positive patients.
Nunnari G, Berretta M, Pinzone MR,  et al
Eur Rev Med Pharmacol Sci. 2012 Sep;16(9):1257-1270.
Abstract

Standardized care management ensures similar survival rates in HIV-positive and HIV-negative patients with hepatocellular carcinoma.
Lim C, Goutte N, Gervais A, Vullierme MP,  et al.

J Acquir Immune Defic Syndr
. 2012 Aug 22
Abstract

The risk of hepatocellular carcinoma among individuals with acquired immunodeficiency syndrome
in the United States.

Sahasrabuddhe VV, Shiels MS, McGlynn KA, Engels EA
Cancer. 2012 Jun 26.
Abstract

The prevalence of cirrhosis and hepatocellular carcinoma in patients with HIV infection.
Ioannou GN, Bryson CL, Weiss NS,  et al

Hepatology
.
2012 Apr 24.
Abstract

Hepatocellular Carcinoma in HIV-Infected Patients: Check Early, Treat Hard.
Berretta M, Garlassi E, Cacopardo B,  et al

Oncologist
. 2011 Aug 25.

Abstract


Liver Fibrosis
       

           Journal Papers, Abstracts, and Commentaries
 
  FULL-TEXT ARTICLE
Exposure to previous cART is associated with significant liver fibrosis and cirrhosis in human immunodeficiency virus-infected patients.
Anadol E, Lust K, Boesecke C, et al
PLoS One
. 2018 Jan 18;13(1):e0191118. 
Paper

FULL-TEXT ARTICLE
Hepatic fibrosis and factors associated with liver stiffness in HIV mono-infected individuals.
Sulyok M, Ferenci T, Makara M, et al
PeerJ. 2017 Jan 11;5:e2867.

Paper

The Role of Current and Historical Alcohol Use in Hepatic Fibrosis Among HIV-Infected Individuals.
Kim HN, Crane HM, Rodriguez CV,  et al
AIDS Behav. 2016 Dec 29.
Abstract

Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV
Matta B, Lee TH, Patel K.

Curr HIV/AIDS Re
p
. 2016 Aug 2.
Abstract

Liver Fibrosis in HIV Patients Receiving a Modern cART: Which Factors Play a Role?
Mohr R, Schierwagen R, Schwarze-Zander C, et al
 
Medicine (
Baltimore)
. 2015 Dec;94(50):e2127
Abstract

Transient elastography for the detection of hepatic fibrosis in HIV-monoinfected adults with elevated aminotransferases on antiretroviral therapy.
Morse CG, McLaughlin M, Proschan M, et al

AIDS
. 2015 Nov;29(17):2297-2302.
Abstract

Liver fibrosis, microbial translocation and immune activation markers in HIV and HCV infections and in HIV/HCV co-infection.
Sacchi P, Cima S, Corbella M,  et al
Dig Liver Dis. 2014 Nov 29
Abstract

Non-invasive fibrosis biomarkers - APRI and Forns - are associated with liver stiffness in HIV-monoinfected patients receiving antiretroviral drugs.
Hasson H, Merli M, Galli L, , et al

Liver Int
. 2013 Mar 8.
Abstract

Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient
elastography and serum biomarkers.
Vermehren J, Vermehren A, Mueller A,  et al

BMC Gastroenterol
. 2012 Mar 27;12(1):27
Abstract

Evaluation of Liver Fibrosis: Concordance Analysis between Noninvasive Scores
(APRI and FIB-4) Evolution and Predictors in a Cohort of HIV-Infected Patients
without Hepatitis C and B Infection.
Mendeni M, Focà E, Gotti D, et al

Clin Infect Dis
. 2011 May;52(9):1164-73.
Abstract

FULL-TEXT PDF ARTICLE
Prevalence and risk factors for significant liver fibrosis among HIV-monoinfected patients.
Dallapiazza M, Amorosa VK, Localio R, Kostman JR, Lo Re V 3rd.

BMC Infect Dis
. 2010 May 13;10(1):116.
Paper


Cholangiopathy
       

         Journal Papers, Abstracts, and Commentaries
 
  HIV/AIDS cholangiopathy: Clinical spectrum, cholangiographic features and outcome in
30 patients.
Devarbhavi H, Sebastian T, Seetharamu SM, Karanth D.
J Gastroenterol Hepatol. 2010 Oct;25(10):1656-60

Abstract
 

Steatohepatitis
       

         Journal Papers, Abstracts, and Commentaries
 
  From nonalcoholic fatty liver to nonalcoholic steatohepatitis and cirrhosis in HIV-infected patients:
diagnosis and management.
Lemoine M, Serfaty L, Capeau J.
Curr Opin Infect Dis. 2012 Feb;25(1):10-6..
Abstract
 

Liver Abscess
       

         Journal Papers, Abstracts, and Commentaries
 
  Metronidazole treatment for acute phase amoebic liver abscess in patients co-infected with HIV.
Ohnishi K, Uchiyama-Nakamura F.
Int J STD AIDS. 2012 Aug;23(8):e1-3.
Abstract
 

 


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