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Pneumocystis
jirovecii (carinii) Pneumonia
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Last Update:  March 07, 2010
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New and Noteworthy
 

March 2010
 

General Reports/Reviews
       

          Journal Papers, Abstracts, and Commentaries

 
Sequence and structure of the linear mitochondrial genome of Pneumocystis carinii.
Sesterhenn TM, Slaven BE, Keely SP,
et al  
Mol Genet Genomics
. 2009 Nov 17
Abstract

FULL-TEXT ARTICLE
The Pneumocystis life cycle.
Aliouat-Denis CM, Martinez A, Aliouat el M,
Mem Inst Oswaldo Cruz. 2009 May;104(3):419-26
Paper

Human reservoirs of Pneumocystis.
Wissmann G, Morilla R, Friaza V, et al
Enferm Infecc Microbiol Clin. 2009 Apr 27
Abstract

Pneumocystis pneumonia: current concepts in pathogenesis, diagnosis, and treatment.
Krajicek BJ, Thomas CF Jr, Limper AH. 

Clin Chest Med
. 2009 Jun;30(2):265-78,
Abstract

Risk factors of Pneumocystis jeroveci pneumonia in patients with systemic lupus erythematosus.
Lertnawapan R, Totemchokchyakarn K, Nantiruj K, Janwityanujit S.
Rheumatol Int. 2009 Mar;29(5):491-6.
Abstract
 

Advances in the biology, pathogenesis and identification of Pneumocystis pneumonia.
Krajicek BJ, Limper AH, Thomas CF Jr, et al
 
Curr Opin Pulm Med.
2008 May;14(3):228-34.
Abstract
 
Pneumocystis pneumonia.
D'Avignon LC, Schofield CM, Hospenthal DR.  
Semin Respir Crit Care Med. 2008 Apr;29(2):132-40
Abstract
 
Pneumocystis: a novel pathogen in chronic obstructive pulmonary disease?
Morris A, Sciurba FC, Norris KA.
COPD. 2008 Feb;5(1):43-51.
Abstract
 
Pneumocystis Colonisation Is Common Among Hospitalized HIV-infected Patients with
Non-Pneumocystis Pneumonia.
Davis JL, Welsh DA, Beard CB, ET AL
Thorax. 2007 Nov 16
Abstract
 
Clinical Picture of Pneumocystis jiroveci Pneumonia in Cancer Patients.
Bollée G, Sarfati C, Thiéry G, et al 
Chest. 2007 Oct;132(4):1305-10.
Abstract
 
Type I interferon signaling and B cells maintain hemopoiesis during Pneumocystis
infection of the lung.
Meissner N, Rutkowski M, Harmsen AL, et al  

J Immunol.
2007 May 15;178(10):6604-15.
Abstract
 
Climate and genotypes of Pneumocystis jirovecii
Miller RF, Evans HE, Copas AJ, Cassell JA

Clin Microbiol Infect.
2007 Apr;13(4):445-8
Abstract
 
Differences and similarities of cytomegalovirus and pneumocystis pneumonia in
HIV-negative immunocompromised patients - thin-section CT-morphology in the early
phase of the disease.
Vogel MN, Brodoefel H, Hierl T, et al

Br J Radiol. 2006 Dec 6;
Abstract
 
FULL-TEXT DOCUMENT
An Official ATS Workshop Summary: Recent Advances and Future Directions in
Pneumocystis Pneumonia (PCP).
Huang L, Morris A, Limper AH, Beck JM.

Proc Am Thorac Soc.
2006 Oct;3(8):655-64.
Paper
 
Human immunodeficiency virus-infected patients with prior pneumocystis pneumonia exhibit
increased serologic reactivity to several major surface glycoprotein clones.
Daly KR, Koch JV, Shire NJ, et al
 
Clin Vaccine Immunol
. 2006 Oct;13(10):1071-1078.
Abstract
 
Pulmonary surfactant in patients with Pneumocystis pneumonia and acquired
immunodeficiency syndrome.
Schmidt R, Markart P, Ruppert C, et  al
  
Crit Care Med.
2006 Jul 17;
Abstract
 
Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after
temozolomide.

Ganiere V, Christen G, Bally F

Nat Clin Pract Oncol. 2006 Jun;3(6):339-43;
Abstract
 
Increased risk of Pneumocystis carinii and community-acquired pneumonia with
tobacco use in HIV disease.
Miguez-Burbano MJ, Ashkin D, Rodriguez A, Duncan R 
 
Int J Infect Dis
. 2005 Jul;9(4):208-17.
Abstract
 
Is Pneumocystis carinii pneumonia after stem cell transplantations a contagious
disease?
Resnck IB, Averbuch D, Aker M, Engelhard D 
 
Clin Transplant.
2005 Jun;19(3):427-31.
Abstract
 
Immunity against the opportunistic fungal pathogen Pneumocystis.
Steele C, Shellito JE, Kolls JK.et al
Med Mycol. 2005 Feb;43(1):1-19. R
Abstract
 
Role of Type I IFNs in Pulmonary Complications of Pneumocystis murina Infection.
Meissner NN, Swain S, Tighe M, et al   
Immunol. 2005 May 1;174(9):5462-71
Abstract
 
Pneumocystis carinii pneumonia in patients with solid tumors and lymphomas:
predisposing factors and outcome.
Barbounis V, Aperis G, Gambletsas E,et al
Anticancer Res. 2005 Jan-Feb;25(1B):651-
Abstract
 
Severity and outcome of HIV-associated Pneumocystis pneumonia containing
Pneumocystis jirovecii dihydropteroate synthase gene mutations.
Crothers K, Beard CB, Turner J, et al

AIDS
. 2005 May 20;19(8):801-805.
Abstract
 
Can data from an electronic medical record identify which patients with pneumonia have
Pneumocystis carinii Infection?
Diero L, Stiffler T, Einterz RM, Tierney WM.
 
Int J Med Inform. 2004 Nov;73(11-12):743-50.
Abstract
 
FULL-TEXT ARTICLE
Dihydropteroate Synthase Gene Mutations in Pneumocystis and Sulfa Resistance,
Huang L, Crothers K, Atzori C,

Emerg
Infect Dis  2004 Oct
Paper
 
Invasive Pneumococcal Disease in Patients Infected with HIV: Still a Threat in the Era
of Highly Active Antiretroviral Therapy.
Jordano Q, Falco V, Almirante B, et al
.
 
Clin Infect Dis. 2004 Jun 1;38(11):1623-8.
Abstract
 
        Conference Reports, Abstracts, and Posters
 
  Genetic Characterization of Drug Targets-Dihydropteroate Sinthase (DHPS) and
Dihydrofolate Reductase (DHFR) in Pneumocystis jirovecii Isolates in Portugal
M.C. COSTA, F. ESTEVES, F. ANTUNES , O. MATOS; 
(45 ICAAC)
Abstract

Cofactors
       

Drugs
 
     Infliximab

          Journal Papers, Abstracts, and Commentaries
 

 
Pneumocystis jiroveci pneumonia during infliximab therapy
Josephson ME, Kristensen LH, Andersen VC.
 
Ugeskr Laeger.
2008 Jun 9;170(24):2159-60
Abstract

Pneumocystis jiroveci (carinii) Pneumonia After Infliximab Therapy: A Review of
84 Cases.
Kaur N, Mahl TC.  

Dig Dis Sci.
2007 Apr 11;
Abstract
 

HIV-Associated Pneumocystis Pneumonia 

          Journal Papers, Abstracts, and Commentaries

 
Long-Term Serologic Responses to the Pneumocystis jirovecii Major Surface Glycoprotein in HIV-Positive
Individuals With and Without P. jirovecii Infection.
Walzer PD, Djawe K, Levin L, Daly KR, et al 

J Infect Dis
. 2009 Mar 19.

Abstract
 
Increased risk of Pneumocystis carinii and community-acquired pneumonia with
tobacco use in HIV disease.
Miguez-Burbano MJ, Ashkin D, et al

Int J Infect Dis.
2005 May 22;
Abstract
 
Invasive Pneumococcal Disease in Patients Infected with HIV: Still a Threat in the
Era of Highly Active Antiretroviral Therapy.
Jordano Q, Falco V, Almirante B, et al
.
 
Clin Infect Dis. 2004 Jun 1;38(11):1623-8.
Abstract
 
Complementation and characterization of the Pneumocystis carinii MAPK, PCM.
Vohra PK, Puri V, Thomas CF.
FEBS Lett. 2003 Sep 11;551(1-3):139-146.
Abstract
 
Pneumocystis carinii pneumonia in HIV-infected patients in the HAART era.
Pulvirenti J, Herrera P, Venkataraman P, Ahmed N.

AIDS Patient Care S
TDS. 2003 Jun;17(6):261-5.
Abstract
 
Malignancy-Associated Pneumocystis carinii Infection

          Journal Papers, Abstracts, and Commentaries

  Pneumocystis carinii pneumonia in patients with hematologic malignancies: a descriptive study.
Roblot F, Le Moal G, Godet C, et al.
J Infect. 2003 Jul;47(1):19-27
Abstract

Diagnosis/Diagnostics

         Journal Papers, Abstracts, and Commentaries

 
Diagnostic significance of nested polymerase chain reaction for sensitive detection of Pneumocystis
jirovecii in respiratory clinical specimens.
Gupta R, Mirdha BR, Guleria R, et al  
Diagn Microbiol Infect Dis. 2009 Aug;64(4):381-8.
Abstract

Molecular diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients.
Jarboui MA, Sellami A, Sellami H, et al 

Mycoses
. 2009 Jun 1.
Abstract

Real-time PCR is more specific than conventional PCR for induced sputum diagnosis of
Pneumocystis pneumoniain immunocompromised patients without HIV infection.
Fujisawa T, Suda T, Matsuda H, et al  

Respirology
. 2009 Mar;14(2):203-9
Abstract

Polymerase chain reaction for diagnosing pneumocystis pneumonia in non-HIV immunocompromised
patients with pulmonary infiltrates.
Azoulay E, Bergeron A, Chevret S, et al

Chest
. 2009 Mar;135(3):655-61.
Abstract
 
Use of different primer directed sequence amplification by polymerase chain reaction for identification of
Pneumocystis jirovecii in clinical samples.
Gupta R, Mirdha BR, Guleria R, et al  
Indian J Chest Dis Allied Sci. 2008 Oct-Dec;50(4):321-7.
Abstract
 
Efficacy of 99mTc-DTPA Lung Clearance Test in the Diagnosis of PCP in HIV-Positive Patients.
Deep A, Bhure SU, Bhure UN, et al
 
J Trop Pediatr.
2008 Sep 9.
Abstract
 
FULL TEXT ARTICLE
Induced sputum versus bronchoalveolar lavage in the diagnosis of pneumocystis jiroveci
pneumonia in human immunodeficiency virus-positive patients.

Silva RM, Bazzo ML, Borges AA.
Braz J Infect Dis. 2007 Dec;11(6):549-53.
Paper
 
Sensitive detection of Pneumocystis jirovecii DNA in gastric wash using nested
polymerase chain reaction.
Limawongpranee S, Wanachiwanawin D, Chokephaibulkit K, et al
Southeast Asian J Trop Med Public Health. 2007 Sep;38(5):892-6.
Abstract
 
FlindersTechnology Associates (FTA) filter paper-based DNA extraction with polymerase
chain reaction (PCR) for detection of Pneumocystis jirovecii from respiratory specimens of
immunocompromised patients.

Nuchprayoon S, Saksirisampant W, Jaijakul S, Nuchprayoon I.
J Clin Lab Anal. 2007;21(6):382-6.
Abstract
 
Development and evaluation of a real-time PCR assay for detection of Pneumocystis
jirovecii DNA in bronchoalveolar lavage fluid of HIV-infected patients.
Huggett JF, Taylor MS, Kocjan G, et al

Thorax.
2007 Aug 10;
Abstract
 
Polymerase chain reaction detection of Pneumocystis jiroveci: evaluation of 9 assays.
Robberts FJ, Liebowitz LD, Chalkley LJ.
 
Diagn Microbiol Infect Dis.
2007 Aug;58(4):385-92.
Abstract
 
Development and evaluation of a real-time PCR assay for detection of Pneumocystis jiroveci.
Bandt D, Monecke S. 

Transpl Infect Dis.
2007 Jul 1;
Abstract
 
Performance of a molecular viability assay for the diagnosis of Pneumocystis pneumonia in
HIV-infected patients.
de Oliveira A, Unnasch TR, Crothers K, et al 
Diagn Microbiol Infect Dis. 2006 Oct 16
Abstract
 
Pneumocystis jiroveci in HIV/AIDS patients: detection by FTA filter paper together with PCR
in noninvasive induced sputum specimens.
Jaijakul S, Saksirisampant W, Prownebon J,   et a
l:
J Med Assoc Thai. 2005 Sep;88 Suppl 4:S294-9.
Abstract

Pneumocystis pneumonia revisited: Delayed diagnosis in an HIV infected individual with
high blood and low lung CD4 T cell counts.
Killingley B, Breen R, Lipman M, Johnson M.
J Infect. 2006 Jan 2
Abstract

Molecular diagnosis of Pneumocystis pneumonia.
Durand-Joly I, Chabe M, Soula F, et al  
FEMS Immunol Med Microbiol. 2005 Jul 29;
Abstract

Low Sensitivity of a Nested Polymerase Chain Reaction in Oropharyngeal
Washings for the Diagnosis of Pneumocystis Pneumonia in HIV-Infected Patients.
Nyamande K, Lalloo UG, York D, et al  

Chest.
2005 Jul;128(1):167-71.
Abstract
 
Quantitative TaqMan PCR for detection of Pneumocystis jiroveci.
Brancart F, Rodriguez-Villalobos H, Fonteyne PA, et al
 
J Microbiol Methods.
2005 Jun;61(3):381-7.
Abstract
 
Quantitative TaqMan PCR for detection of Pneumocystis jiroveci.
Brancart F, Rodriguez-Villalobos H, et al
J Microbiol Methods. 2005 Jun;61(3):381
Abstract
 
FULL-TEXT ARTICLE
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia,
Beard CB, Roux P, Nevez G, , et al

Emerg
Infect Dis  2004 Oct
Paper
 
PCR diagnosis of Pneumocystis carinii on sputum and bronchoalveolar lavage samples in
immunocompromised patients.
Pinlaor S, Mootsikapun P, Pinlaor P, et al 

Parasitol Res.
2004 Sep 1
Abstract
 
A Prospective, Blinded Study of Quantitative Touch-Down Polymerase Chain Reaction Using
Oral-Wash Samples for Diagnosis of Pneumocystis Pneumonia in HIV-Infected Patients.
Larsen HH, Huang L, Kovacs JA, et al

J Infect Dis. 2004 May 1;189(9):1679-83.
Abstract
 
Detection of Pneumocystis carinii by DNA amplification in patients with connective tissue
diseases: re-evaluation of clinical features of P. carinii pneumonia in rheumatic diseases.
Saito K, Nakayamada S, Nakano K, et al.
Rheumatology (Oxford). 2004 Feb 3
Abstract

The Utility of Sputum Induction for Diagnosis of Pneumocystis Pneumonia in
Immunocompromised Patients without Human Immunodeficiency Virus.
LaRocque RC, Katz JT, Perruzzi P, Baden LR.
Clin Infect Dis. 2003 Nov 15;37(10):1380-3.
Abstract

Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii
pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients.

Hidalgo A, Falco V V, Mauleon S, et al.
Eur Radiol
2003 May;13(5):1179-1184
Abstract

Induced sputum for diagnosing Pneumocystis carinii pneumonia in HIV patients:
new data, new issues.
Turner D, Schwarz Y, Yust I., et al.
 
Eur Respir J
2003 Feb;21(2):204-8
Abstract

FULL-TEXT ARTICLE

Detection of Pneumocystis DNA in samples from patients suspected of bacterial
pneumonia- a case-control study
Helweg-Larsen J, Jensen JS,  Dohn B, et al.
BMC Infectious Diseases 2002 2:28
Paper

Meta-analysis of diagnostic procedures for Pneumocystis carinii pneumonia in HIV-1-
infected patients.

Cruciani M, Marcati P, Malena M,  
Eur Respir J
2002 Oct;20(4):982-9
Abstract
 
Effect of oral washes on the diagnosis of Pneumocystis carinii pneumonia with a
low parasite burden and on detection of organisms in subclinical infections.
Matos O, Costa MC, Lundgren B, et al. 
Eur J Clin Microbiol Infect Dis 2001Aug;20(8):573-5
Abstract
 
Induced sputum: opening a new window to the lung.
Fireman E.
Sarcoidosis Vasc Diffuse Lung Dis 2001 Oct;18(3):263-71
Abstract
 
FULL-TEXT ARTICLE [algorithm]
Performance of an algorithm to detect Pneumocystis carinii pneumonia in
symptomatic HIV-infected persons. Pulmonary Complications of HIV Infection
Study Group

Huang L, Stansell J, Osmond D. et al.

C
hest 1999 Apr;115(4):1025-32
Paper

 


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