Medical Advocates

Toxoplasmosis
  Drugs
            
Antiretrovirals              
 
Atovaquone
Cotrimoxazole
Dexamathasone

Diclazuril
Isavuconazole
Itraconazole
Pyrimethamine
Sulfadiazine

 
Trimethoprim/Sulfamethoxazole
Voriconazole




 

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Last Update:  December 06, 2016
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Antiretrovirals
       

    Journal Papers, Abstracts, and Commentaries

  Antibiotics for human toxoplasmosis: a systematic review of randomized trials.
Rajapakse S, Chrishan Shivanthan M,  et al  
Pathog Glob Health. 2013 Jun;107(4):162-9.
Abstract

Restoration of T Cell Responses to Toxoplasma gondii after Successful Combined Antiretroviral Therapy in Patients
with AIDS with Previous Toxoplasmic Encephalitis.
Lejeune M, Miró JM, De Lazzari E, et al
Clin Infect Dis. 2011 Mar;52(5):662-670..
Abstract


Atovaquone
       

    Journal Papers, Abstracts, and Commentaries

  Atovaquone for Prophylaxis of Toxoplasmosis after Allogeneic Hematopoietic Stem Cell Transplantation.
Mendorf A, Klyuchnikov E, Langebrake C, et al
Acta Haematol
. 2015 May 5;134(3):146-154.
Abstract

Effects of atovaquone and astragalus combination on the treatment and IL-2, IL-12, IFN-γ levels on mouse models of acute toxoplasmosis.
Sönmez N, Büyükbaba Boral O, Kaşali K, Tekeli F.
Mikrobiyol Bul. 2014 Oct;48(4):639-51
Abstract

FULL-TEXT ARTICLE
Toxoplasmosis complications and novel therapeutic synergism combination of diclazuril plus atovaquone.
Oz HS.
Front Microbiol. 2014 Sep 15;5:484.
Paper

FULL-TEXT ARTICLE
Atovaquone ameliorate gastrointestinal toxoplasmosis complications in a pregnancy model.
Oz HS, Tobin T.
Med Sci Monit. 2012 Sep;18(9):BR337-45.
Paper


Cotrimoxazole
       

    Journal Papers, Abstracts, and Commentaries

 
Cotrimoxazole for treatment of cerebral toxoplasmosis: an observational cohort study during 1994-2006.
Béraud G, Pierre-François S, Foltzer A, et al 

Am J Trop Med Hyg. 2009 Apr;80(4):583-7.
Abstract

Diclazuril
       

    Journal Papers, Abstracts, and Commentaries

  FULL-TEXT ARTICLE
Toxoplasmosis complications and novel therapeutic synergism combination of diclazuril plus atovaquone.
Oz HS.
Front Microbiol. 2014 Sep 15;5:484.
Paper

Dexamathasone
       

    Journal Papers, Abstracts, and Commentaries

  Cytokine and antibody responses of reactivated murine toxoplasmosis upon administration
of dexamathasone
.
Kang KN, Choi IU, Shin DW, Lee YH.
Korean J Parasitol. 2006 Sep;44(3):209-19
Abstract

Isavuconazole
       

    Journal Papers, Abstracts, and Commentaries

  Cost-Effectiveness Analysis of Isavuconazole vs. Voriconazole as First-Line Treatment for Invasive Aspergillosis.
Harrington R, Lee E, Yang H, Wei J,
et al
Adv Ther
. 2016 Dec 2.

Abstract

Itraconazole
       

    Journal Papers, Abstracts, and Commentaries

  Heart failure induced by itraconazole.
Rodrigo-Troyano A, Mediavilla MM, et al
Med Clin (Barc). 2016 Nov 30.
Abstract

Itraconazole affects Toxoplasma gondii endodyogeny.
Martins-Duarte Edos S, de Souza W, Vommaro RC.
FEMS Microbiol Lett. 2008 May;282(2):290-8.
Abstract


Pyrimethamine
       

    Journal Papers, Abstracts, and Commentaries

  Drug monitoring of pyrimethamine during maintenance therapy of toxoplasmic
encephalitis in patients with advanced HIV infection during HAART.
Langmann P, Schirmer D, Zilly M, Klinker H. 

Med Sci Monit.
2004 May;10(5):PI65-9.
Abstract

Sulfadiazine
       

    Journal Papers, Abstracts, and Commentaries

  Primary prevention with cotrimoxazole for HIV-1-infected adults: results of
the pilot study in Dakar,
Senegal.Maynart M, Lievre L, Sow PS, et al.

J Acquir Immune Defic Syndr
2001 Feb 1;26(2):130-6
Abstract

Trimethoprim/Sulfamethoxazole
       

    Journal Papers, Abstracts, and Commentaries

  A systematic review and meta-analysis of the relative efficacy and safety of treatment regimens for HIV-associated cerebral toxoplasmosis: is trimethoprim-sulfamethoxazole a real option?
Hernandez AV, Thota P, Pellegrino D, et al
HIV Med. 2016 Jun 28.
Abstract

Trimethoprim-sulfamethoxazole versus placebo to reduce the risk of recurrences of toxoplasma gondii retinochoroiditis: randomized controlled clinical trial.
Fernandes Felix JP, Cavalcanti Lira RP, et al
Am J Ophthalmol. 2014 Jan 2.
Abstract
 


Voriconazole
       

    Journal Papers, Abstracts, and Commentaries

  Cost-Effectiveness Analysis of Isavuconazole vs. Voriconazole as First-Line Treatment for Invasive Aspergillosis.
Harrington R, Lee E, Yang H, Wei J,
et al
Adv Ther
. 2016 Dec 2.

Abstract

 


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