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Toxoplasmosis
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Last Update:  September 18, 2017
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New and Noteworthy
     

August 2017
 
 

General Reports
       

          Books

  ONLINE BOOK
HIV-1 Associated Opportunistic Infections, Toxoplasmosis.
Ayoade F, Dulebohn S.
StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing;

 

          Journal Papers, Abstracts, and Commentaries

 

FULL-TEXT ARTICLE
Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis.
Palencia A, Bougdour A, Brenier-Pinchart MP, et al
EMBO Mol Med. 2017 Feb 1. pii: e201607370.
Paper

Toxoplasmosis and cancer: Current knowledge and research perspectives.
Vittecoq M, Thomas F.
Bull Soc Pathol Exot. 2016 Sep 2.
Abstract

FULL-TEXT ARTICLE
Toxoplasmosis in immunosuppressed patients.
Lewis JM, Clifford S, Nsutebu E.
Rheumatology (Oxford)
. 2015 May 11
Paper

Extracerebral Toxoplasmosis: Looking Beyond the Central Nervous System.
Lewis O, Shokrani B, Saumil D, Phillpotts M.
Chest
. 2014 Oct 1;146(4_MeetingAbstracts):182A.
Abstract

Survival of experimentally induced Toxoplasma gondii tissue cysts in vacuum packed goat meat and dry fermented goat meat sausages
Neumayerová H, Juránková J, Saláková A,  et al
Food Microbiol. 2014 May;39:47-52.
Abstract

FULL-TEXT ARTICLE

Features to validate cerebral toxoplasmosis.
Correia Cda C, Melo HR, Costa VM, Brainer AM.
Rev Soc Bras Med Trop. 2013
Paper

Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains.
Xiao J, Li Y, Jones-Brando L, Yolken RH.
J Neural Transm
. 2013 Jul 3.
Abstract

FULL-TEXT ARTICLE
Toxoplasma gondii Proliferation Require Down-Regulation of Host Nox4 Expression via Activation of PI3 Kinase/Akt Signaling Pathway.
Zhou W, Quan JH, Lee YH,  et al
PLoS One
.
2013 Jun 18;8(6):
Paper

FULL-TEXT ARTICLE
Toxoplasmosis-Associated Difference in Intelligence and Personality in Men Depends on Their Rhesus Blood Group but Not ABO Blood Group.
Flegr J, Preiss M, Klose J.
PLoS One. 2013 Apr 10;8(4):e61272.
Paper

Differences in onset of disease and severity of psychopathology between toxoplasmosis-related and toxoplasmosis-unrelated schizophrenia.
Holub D, Flegr J, Dragomirecká E, Rodriguez M, et al
Acta Psychiatr Scand. 2012 Nov 5. .
Abstract

FULL-TEXT ARTICLE
Redefining chronic toxoplasmosis-a T cell exhaustion perspective.
Bhadra R, Khan IA.
PLoS Pathog. 2012 Oct;8(10):
Paper

 

        Conference Reports, Abstracts, and Posters

  Immune Recovery under HAART is Associated with Restoration of Lymphocyte Proliferation and  Gamma-Interferon Production in Presence of Toxoplasma gondii
Antigens

(41 ICAAC)

Abstract

Pathogenesis
 

          Journal Papers, Abstracts, and Commentaries

  Pathogenesis of toxoplasmosis.
Bhopale GM.
Comp Immunol Microbiol Infect Dis 2003 Jul;26(4):213-22
Abstract
 
  Immunopathogenesis of Cerebral Toxoplasmosis.
Suzuki Y.

J Infect Dis
2002 Dec 1;186 Suppl 2:S234-S240
Abstract
 

Case Studies/Literature Reviews
       

          Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
Cerebral Toxoplasmosis Masquerading Cns Lymphoma on FDG PET-CT in Post Renal Transplant Patient.
\
Mukherjee A, Bal C, Tripathi M,
 et al
I
ndian J Nucl Med
. 2017 Apr-Jun;32(2):148-149.

Paper

Late-Onset Cerebral Toxoplasmosis After Allogeneic Hematopoietic Stem Cell Transplantation.
Khalaf AM, Hashim MA, Alsharabati M,  et al
Am J Case Rep. 2017 Mar 10;18:246-250.
Abstract

FULL-TEXT ARTICLE
Toxoplasmosis-associated IRIS involving the CNS: a case report with longitudinal analysis of T cell subsets.
Rb-Silva R, Nobrega C, Reiriz E, et al
BMC Infect Dis. 2017 Jan 13;17(1):66.
Paper

Toxoplasmosis versus lymphoma: Cerebral lesion characterization using DSC-MRI revisited.
Dibble EH, Boxerman JL, Baird GL,  et al 

Clin Neurol Neurosurg
. 2016 Dec 2;152:84-89.
Abstract

Case Series Study of Invasive Pulmonary Aspergillosis.
Aller-García AI, Castro-Méndez C, Alastruey-Izquierdo A,  et al
Mycopathologia. 2016 Dec 2.
Abstract

A matched case-control study of toxoplasmosis after allogeneic haematopoietic stem cell transplantation: still a devastating complication.
Conrad A, Le Maréchal M, Dupont D,  et al
Clin Microbiol Infect. 2016 May 9.
Abstract

FULL-TEXT ARTICLE
A Novel Case of Solitary Cerebral Toxoplasmosis Mimicking Glioblastoma as the First Presentation of HIV.
Ruiz ML.
J Clin Neurol. 2016 Apr;12(2):248-250
Paper

FULL-TEXT PDF ARTICLE
Encephalitis caused by an unusual HHV-6 - Toxoplasma gondii coinfection in a cord blood transplant recipient.
Chapuis A, Chabrot C, Mirand A, et al

Int J Infect Dis
. 2016 Apr 6.
Paper

Intracranial toxoplasmosis presenting as panhypopituitarism in an immunocompromised patient.
Hamdeh S, Abbas A, Fraker J, Lambrecht JE.
Am J Emerg Med
. 2015 May 9.
Abstract

Toxoplasma gondii meningoencephalitis without cerebral MRI findings in a patient with ulcerative colitis under immunosuppressive treatment.
Assimakopoulos SF, Stamouli V, Dimitropoulou D, et al
Infection. 2015 Jan 27.
Abstract

Acute Confusional State: A Manifestation of Toxoplasma and CMV Co-infection in HIV Patient.
Jehangir W, Sareen R, Sen S,  et al
N Am J Med Sci
. 2014 Oct;6(10):545-548..
Abstract

Seizure as an initial presentation of human immunodeficiency virus: acute toxoplasmosis mimicking glioblastoma multiforme.
Parekh P, Boggs JP, Silverberg M, Marik P.
BMJ Case Rep. 2013 Nov 14;2013..
Abstract

Predominantly periventricular necrotizing encephalitis due to toxoplasmosis: two unusual cases and review of literature.
Lummus S, Kleinschmidt-Demasters BK."
Clin Neuropathol
. 2013 Sep 2..
;
Abstract

Toxoplasma gondii impairs memory in infected seniors.
Gajewski PD, Falkenstein M, Hengstler JG, Golka K.
Brain Behav Immun. 2013 Dec 6
Abstract

Severe polymyositis due to Toxoplasma gondii in an adult immunocompetent patient: a case report and review of the literature.
Cuomo G, D'Abrosca V, Rizzo V,  et al
Infection. 2013 Apr 1
Abstract

FULL-TEXT ARTICLE
Cerebral Toxoplasmosis Mimicking Subacute Meningitis in HIV-Infected Patients; a Cohort Study from Indonesia.
Ganiem AR, Dian S, Indriati A,  et al
PLoS Negl Trop Dis
. 2013 Jan;7(1):e1994
Paper

Chorioretinitis as the First Sign of Acquired Toxoplasmosis Transmitted from Donor following Kidney Transplantation: Case Report and Review of the Literature.
Filloy A, Garcia-Garcia O, Fernández-Lorente L.
Ocul Immunol Inflamm
. 2013 Feb;21(1):27-8
Abstract

Disseminated toxoplasmosis presenting as septic shock five weeks after renal transplantation.
Vaughan LB, Wenzel RP.
Transpl Infect Dis. 2012 Dec 20.

Abstract

Toxoplasmic cyst and heart transplant: a case report of serological reactivation in an acute graft rejection context.
Desoubeaux G, Perret-Gallix K, Machet MC, et al
Ann Biol Clin (P
aris)
. 2012 Jun 1;70(3):323-328.
Abstract


Toxoplasmosis in cord blood transplantation recipients.
Bautista G, Ramos A, Forés R,  et al
Transpl Infect
Dis
. 2012 May
Abstract

Toxoplasmosis myelopathy and myopathy in an AIDS patient: a case of immune reconstitution
inflammatory syndrome?
Kung DH, Hubenthal EA, Kwan JY,  et al
Neurologist
. 2011 Jan;17(1):49-51.
Abstract

Solitary Hypothalamopituitary Toxoplasmosis Abscess in a Patient with AIDS.
Legrand L, Catherine L, Brivet F, Musset D.
AJNR Am J Neuroradiol. 2010 May 27
Abstract

FULL-TEXT ARTICLE
Acute pericarditis and myocarditis by Toxoplasma gondii in an immunocompetent
young man: a case report.

Pergola G, Cascone A, Russo M.

Infez Med
. 2010 Mar;18(1):48-52.
Paper

Correlation of parasite load by quantitative PCR and clinical outcome in a heart transplant patient with disseminated toxoplasmosis.
Patrat-Delon S, Gangneux JP, Lavoué S, et al
J Clin Microbiol
. 2010 May 12.
Abstract

Primary intraocular (retinal) lymphoma following ocular toxoplasmosis.
Sauer TC, Meyers SM, Shen D, Vegh S,et al
Retin Cases Brief Rep. 2010 Apr 1;4(2):160-163.
Abstract

 

Prevention   
Prophylaxis Vaccine    

Prophylaxis

     Journal Papers, Abstracts, and Commentaries

 
Failure of primary atovaquone prophylaxis for prevention of toxoplasmosis in hematopoietic cell transplant recipients.
Gajurel K, Gomez CA, Dhakal R,  et al

Transpl Infect Dis
. 2016 Mar 26.
Abstract

Toxoplasma prophylaxis in haematopoietic cell transplant recipients: a review of the literature and recommendations.
Gajurel K, Dhakal R, Montoya JG.
Curr Opin Infect Dis. 2015 Aug;28(4):283-92
Abstract

Atovaquone for Prophylaxis of Toxoplasmosis after Allogeneic Hematopoietic Stem Cell Transplantation.
Mendorf A, Klyuchnikov E, Langebrake C, et al
Acta Haematol
. 2015 May 5;134(3):146-154.
Abstract

   

Vaccine

    Journal Papers, Abstracts, and Commentaries

 
Enhancing immune responses to a DNA vaccine encoding Toxoplasma gondii GRA14 by Calcium Phosphate nanoparticles as an adjuvant.
Ahmadpour E, Sarvi S, Soteh MB,  et al  

Immunol Lett
.
2017 Mar 9.
Abstract

Development of Toxoplasma gondii vaccine: A global challenge.
Verma R, Khanna P.
Hum Vaccin Immunother
. 2012 Oct 30;9(2).
Abstract

FULL-TEXT ARTICLE
Vaccines against Toxoplasma gondii: challenges and opportunities.
Jongert E, Roberts CW, Gargano N, 
Mem Inst Oswaldo Cruz.
2009 Mar;104(2):252-66.
Paper


Diagnosis/Monitoring
       

   Journal Papers, Abstracts, and Commentaries

 
Proposed panel of diagnostic tools for accurate temporal classification of symptomatic T. gondii infection.
Barros GB, Lemos EM, E Silva-Dos-Santos PP,  et al
J Immunol Methods. 2017 Sep 4.
Abstract

The standardization of 5 immunoassays for anti-Toxoplasma immunoglobulin G(IgG).
Zhang K, Lin G, Han Y, Li J.
Clin Chim Acta. 2017 Jul 7.
Abstract

PCR-RFLP based genotyping of Indian isolates of Toxoplasma gondii.
Rather HA, Din MM, Sheikh AA, et al 

J Parasit Dis
. 2017 Jun;41(2):551-556.

Abstract

Help in the choice of automated or semi-automated immunoassays for the serological diagnosis of toxoplasmosis: Evaluation of nine immunoassays by the French National reference center for toxoplasmosis.
Villard O, Cimon B, L'Ollivier C,  et al

J Clin Microbiol
. 2016 Oct 12.
Abstract

P35 and P22 Toxoplasma gondii antigens abbreviate regions to diagnose acquired toxoplasmosis during pregnancy: toward single-sample assays.
Costa JG, Peretti LE, García VS,  et al
Clin Chem Lab Med. 2016 Sep 22
Abstract

Evaluation of Propranolol Effect on Experimental Acute and Chronic Toxoplasmosis using Q-PCR.
Montazeri M, Ebrahimzadeh MA, Ahmadpour E, et al
Antimicrob Agents Chemother. 2016 Sep 19
Abstract

Serological diagnosis of toxoplasmosis and standardization.
Zhang K, Lin G, Han Y, Li J.

Clin Chim Acta
. 2016 Jul 25.
Abstract

FULL-TEXT ARTICLE
Performance Testing of PCR Assay in Blood Samples for the Diagnosis of Toxoplasmic Encephalitis in AIDS Patients from the French Departments of America and Genetic Diversity of Toxoplasma gondii: A Prospective and Multicentric Study
Ajzenberg D, Lamaury I, Demar M, et al

PLoS Negl Trop D
is
. 2016 Jun 29;10(6):
Paper

Towards Universal Screening for Toxoplasmosis: Rapid, Cost-effective and Simultaneous Detection of Toxoplasma Anti-IgG, IgM and IgA Antibodies Using Very Small Serum Volumes.
Augustine SA.

J Clin Microbiol
.
2016 May 11

Abstract

FULL-TEXT ARTICLE
Molecular diagnosis of Toxoplasma gondii infection in Libya.
Gashout A, Amro A, Erhuma M, et al  

BMC Infect Dis
. 2016 Apr 16;16(1):157.

Paper

Multiplexed Anti-Toxoplasma IgG, IgM and IgA Assay on Plasmonic Gold Chips: Towards Making Mass Screening Possible with Dye Test Precision.
Li X, Pomares C, Gonfrier G, Koh B, et al 

J Clin Microbiol
. 2016 Mar 23.
Abstract

Genotyping of Toxoplasma gondii: DNA extraction from formalin-fixed paraffin-embedded autopsy tissues from AIDS patients who died by severe disseminated toxoplasmosis.
Bastos da Silva I, Pimental de Andrade Batista T,  et al
Exp Parasitol. 2016 Mar 9.
Abstract

Immunodiagnosis and molecular validation of Toxoplasma gondii-recombinant dense granular (GRA) 7 protein for the detection of toxoplasmosis in patients with cancer
Arab-Mazar Z, Fallahi S, Koochaki A, er a
l
Microbiol Res
. 20
16 Feb;183:53-9.
Abstract

Unexpected Diagnosis of Cerebral Toxoplasmosis by 16S and D2 Large-Subunit Ribosomal DNA PCR and Sequencing.
Kruse AY, Kvich L, Eickhardt S, et al
J Clin Microbiol.
2015 Jun;53(6):1983-5.
Abstract

Assessment of the ISAGA A assay for the diagnosis of congenital toxoplasmosis on a series of 145 toxoplasmic seroconversions.
Murat JB, Souvignet A, Fricker-Hidalgo H, et al
Clin Vaccine Immunol
.
2015 Feb 11
Abstract

A 10-year retrospective comparison of two target sequences, REP-529 and B1, for Toxoplasma gondii detection by quantitative PCR.
Belaz S, Gangneux JP, Dupretz P, et al
J Clin Microbiol
. 2015 Feb 4.
Abstract

Identification of Toxoplasma gondii antigens associated with different types of infection by serum antibody profiling.
Felgner J, Juarez S, Hung C,  et al
Parasitology
. 2015 Jan 14:1-12
Abstract

Specific IgM, IgG and IgG1 directed against Toxoplasma gondii detected by flow cytometry and their potential as serologic tools to support clinical indirect fundoscopic presumed diagnosis of ocular disease.
Martins LM, Rangel AL, Peixe RG,  et al
J Immunol Methods
.
2014 Dec 16. pii: S0022-1759(14)00365-2.
Abstract

Determination of parasitic load in different tissues of murine toxoplasmosis after immunization by excretory secretory antigens using Real time QPCR.
Daryani A, Sharif M, Dadimoghaddam Y, et al
Exp Parasitol. 2014 May 19.
Abstract

FULL-TEXT ARTICLE
Diagnosis of antigenic markers of acute toxoplasmosis by IgG avidity immunoblotting.
Ali-Heydari S, Keshavarz H, Shojaee S, Mohebali M.
Parasite. 2013;20:18
Paper

Evaluation of Recombinant SAG1 Protein for Detection of Toxoplasma gondii Specific Immunoglobulin M by ELISA Test.
Jalallou N, Bandehpour M, Khazan H,
Iran J Parasitol. 2012;7(4):17-21.
Abstract

FULL-TEXT ARTICLE
Identification of Toxoplasma gondii Genes Responsive to the Host Immune Response during In Vivo Infection.
Skariah S, Mordue DG.
PLoS One. 2012;7(10):e46621.
Paper

Identification of Toxoplasma gondii in-vivo induced antigens by cDNA library immunoscreening with chronic
toxoplasmosis sera.

Amerizadeh A, Idris ZM, Yin KB, et al
Microb Pathog
. 2012 Oct 5.
Abstract

Epidemiology of and diagnostic strategies for toxoplasmosis.
Robert-Gangneux F, Dardé ML.
Clin Microbiol Rev
. 2012 Apr;25(2):264-96.
Abstract

rROP2(186-533): A Novel Peptide Antigen for Detection of IgM Antibodies Against Toxoplasma gondii.
Liu L, Liu T, Yu L, et al
Foodborne Pathog Dis. 2012 Jan;9(1):7-12.
Abstract

Evaluation of a recombinant multi-epitope peptide for serodiagnosis of Toxoplasma gondii infection.
Dai J, Jiang M, Wang Y,  et al
Clin Vaccine Immunol. 2012 Jan 4.
Abstract

Development of an immunochromatographic strip for the rapid detection of Toxoplasma gondii circulating antigens.
Wang YH, Li XR, Wang GX, et al
Parasitol Int
. 2010 Nov 13.
Abstract

 

Clinical Management
       

   Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTICLE
Humans with latent toxoplasmosis display altered reward modulation of cognitive control.

Stock AK, Dajkic D, Köhling HL,
Sci Rep. 2017 Aug 31;7(1):10170.
Paper

Toxoplasmosis in hematopoietic cell transplant recipients.
Gajurel K, Dhakal R, Montoya JG.

Transpl Infect Dis
. 2017 Jun 12.

Abstract

Towards Universal Screening for Toxoplasmosis: Rapid, Cost-effective and Simultaneous Detection of Toxoplasma Anti-IgG, IgM and IgA Antibodies Using Very Small Serum Volumes.
Augustine SA.

J Clin Microbiol
.
2016 May 11

 

Time to initiation of antiretroviral therapy in HIV-infected patients diagnosed with an opportunistic disease: a cohort study.
Deconinck L, Yazdanpanah Y, Gilson R, et al.
HIV Med. 2014 Dec 18. .
Abstract

Predominantly periventricular necrotizing encephalitis due to toxoplasmosis: two unusual cases and review of literature.
Lummus S, Kleinschmidt-Demasters BK.
Clin Neuropathol. 2013 Sep 2
Abstract

Toxoplasma infection, a rare but life-threatening complication after kidney transplantation: report of two cases.
Jugant S, Pernin V, Vetromile F,
et al
Nephrol Ther
. 2012 Oct 8
.
Abstract

FULL-TEXT ARTICLE
Severe pulmonary toxoplasmosis mimicking viral pneumonitis after a third allogeneic stem cell transplantation in a man with acute lymphoblastic leukemia.
Sumi M, Hata S, Sato K,  et al
Intern Med. 2012;51(20):2943-7.
Paper

 

HIV-Associated Toxoplasmosis
Cerebral Toxoplasmosis Ocular Toxoplasmosis Gastric Toxoplasmosis Pulmonary Toxoplasmosis    


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