Medical Advocates

Stavudine
(Zerit)
 
Pediatric Index
 
Resistance
Adverse Events 
Dosage
Treatment
Viral Dynamics


 

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Last Update:  July 08, 2017
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Resistance
       


Journal Papers, Abstracts, and Commentaries  
       
Drug Resistance in Human Immunodeficiency Virus Type-1 Infected Zambian
Children Using Adult Fixed Dose Combination Stavudine, Lamivudine, and
Nevirapine.
Gupta RK, Ford D, Mulenga V,  et al
Pediatr Infect Dis J
. 2010 May 26
Abstract

Selection of Zidovudine resistance mutations and escape of human immunodeficiency virus
type 1 from antiretroviral pressure in Stavudine-treated pediatric patients.
Maxeiner HG, Keulen W, Schuurman R, et al.     
Infect Dis 2002 Apr 15;185(8):1070-6
Abstract

Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals
treated with didanosine and stavudine.
Coakley EP, Gillis JM, Hammer SM.

AIDS 2000; 14: F9-15.

Abstract

 
Adverse Events 
       

    Journal Papers, Abstracts, and Commentaries

  Peripheral Neuropathy in Children on Stavudine Therapy.
Sankhyan N, Lodha R, Sharma S, et al
Indian J Pediatr
. 2014 May 31
Abstract

Lipodystrophy in HIV-infected children is associated with high viral load and low CD4+  -
lymphocyte count  and CD4+ -lymphocyte percentage at baseline and use of protease
 inhibitors   and  stavudine.
Arpadi SM,  Cuff PA, Horlick M, Wang J, Kotler DP.
J Acquir Immune Defic Syndr 2001   May 1;27(1):30-34
Abstract


Dosage/Formulations
       

    Journal Papers, Abstracts, and Commentaries

  FULL-TEXT ARTICLE
Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial.
Mulenga V, Musiime V, Kekitiinwa A,  et al
Lancet Infect Dis
. 2015 Oct 5
Paper

Effect of reducing the paediatric stavudine dose by half: a physiologically-based pharmacokinetic model.
Sy SK, Malmberg R, Matsushima A,
Int J Antimicrob Agents. 2015 Apr;45(4):413
Abstract

FULL-TEXT ARTICLE
Determination of dosing guidelines for stavudine (2',3'-didehydro-3'-deoxythymidine) in children
with human immunodeficiency virus infection.
Kaul S, Kline MW, Church JA, Dunkle LM.
Antimicrob Agents Chemother 2001 Mar;45(3):758-763
Paper

 
Viral Dynamics
 

    Journal Papers, Abstracts, and Commentaries
 

  Virologic Response in Children Treated with Abacavir Compared with Stavudine-Based Antiretroviral Treatment - A South African Multi-Cohort Analysis.
Technau KG, Schomaker M, Kuhn L, et al
Pediatr Infec
t Dis J
. 2013 Dec 30.

Abstract
 


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Stavudine
Pediatric Index