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Stavudine (Zerit)
 
Pediatric Index
 
Resistance
 Adverse Events 
Dosage
 Treatment
 Viral Dynamics


 
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Last Update:  July 08, 2017
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Resistance
       

Journal Papers, Abstracts, and Commentaries  
       
Drug Resistance in Human Immunodeficiency Virus Type-1 Infected Zambian
Children Using Adult Fixed Dose Combination Stavudine, Lamivudine, and
Nevirapine.
Gupta RK, Ford D, Mulenga V,  et al
Pediatr Infect Dis J. 2010 May 26
 Abstract

Selection of Zidovudine resistance mutations and escape of human immunodeficiency virus
type 1 from antiretroviral pressure in Stavudine-treated pediatric patients.
 Maxeiner HG, Keulen W, Schuurman R, et al.     
Infect Dis 2002 Apr 15;185(8):1070-6
Abstract

Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals
treated with didanosine and stavudine.
Coakley EP, Gillis JM, Hammer SM.
AIDS 2000; 14: F9-15.
Abstract
 
Adverse Events 
       

    Journal Papers, Abstracts, and Commentaries

  Peripheral Neuropathy in Children on Stavudine Therapy.
 Sankhyan N, Lodha R, Sharma S, et al
Indian J Pediatr. 2014 May 31
 Abstract

Lipodystrophy in HIV-infected children is associated with high viral load and low CD4+  -
lymphocyte count  and CD4+ -lymphocyte percentage at baseline and use of protease
 inhibitors   and  stavudine.
Arpadi SM,  Cuff PA, Horlick M, Wang J, Kotler DP.
 J Acquir Immune Defic Syndr 2001   May 1;27(1):30-34
 Abstract
Dosage/Formulations
       

    Journal Papers, Abstracts, and Commentaries

  FULL-TEXT ARTICLE
 Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial.
Mulenga V, Musiime V, Kekitiinwa A,  et al
Lancet Infect Dis. 2015 Oct 5
 Paper

 Effect of reducing the paediatric stavudine dose by half: a physiologically-based pharmacokinetic model.
Sy SK, Malmberg R, Matsushima A,
Int J Antimicrob Agents. 2015 Apr;45(4):413
 Abstract

FULL-TEXT ARTICLE
 Determination of dosing guidelines for stavudine (2',3'-didehydro-3'-deoxythymidine) in children
with human immunodeficiency virus infection.
Kaul S, Kline MW, Church JA, Dunkle LM.
Antimicrob Agents Chemother 2001 Mar;45(3):758-763
 Paper
 
Viral Dynamics
 

    Journal Papers, Abstracts, and Commentaries
 
  Virologic Response in Children Treated with Abacavir Compared with Stavudine-Based Antiretroviral Treatment - A South African Multi-Cohort Analysis.
Technau KG, Schomaker M, Kuhn L, et al
Pediatr Infect Dis J. 2013 Dec 30.
 Abstract
 

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