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Stavudine (Zerit)
 
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Last Update:  July 08, 2017
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General Reports
       

    Journal Papers, Abstracts, and Commentaries

 
FULL-TEXT ARTiCLE
 A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa.
 Cassim H, Otwombe K, Lazarus E,  et al  
PLoS One. 2017 Jul 7;12(7):e0180645
 Paper

Estimation of intracellular concentration of stavudine-triphosphate in HIV-infected children given the reduced dose of 0.5 mg/kg twice daily.
Sy SK, Innes S, Derendorf H,  et al
Antimicrob Agents Chemother. 2013 Dec 2.
Abstract
Frequency of stavudine substitution due to toxicity in children receiving antiretroviral treatment in Soweto,
South Africa.
 Palmer M, Chersich M, Moultrie H, et al
AIDS. 2012 Nov 19.
Abstract

Lipodystrophy and reversal of facial lipoatrophy in perinatally HIV-infected children and adolescents after
discontinuation of stavudine.
 Sawawiboon N, Wittawatmongkol O, Phongsamart W, et al
Int J STD AIDS. 2012 Jul;23(7):497-501
 Abstract

Possible Mitochondrial Dysfunction and Its Association with Antiretroviral Therapy Use in |
Children Perinatally Infected with HIV.
Crain MJ, Chernoff MC, Oleske JM,  et al
J Infect Dis. 2010 Jun 9.
Abstract

Effects of the change from Stavudine to tenofovir in human immunodeficiency virus-infected
children treated with highly active antiretroviral therapy: studies on mitochondrial toxicity and
thymic function.
 Rosso R, Nasi M, Di Biagio A, et al
Pediatr Infect Dis J. 2008 Jan;27(1):17-21.
 Abstract

  Conference Reports, Abstracts and Posters

  Implementing D4T phase out in children taking ARVs in Swaziland
F.L. Gonzalez Fernandez, T. Sigudla, N. Mthethwa
{XX International AIDS Conference)
 Abstract
Monotherapy
       

    Journal Papers, Abstracts, and Commentaries

  A phase I/II evaluation of stavudine (d4T) in children with human immunodeficiency
virus infection.
Kline MW, Dunkle LM, Church JA et al
Pediatrics 1995; 96:2 Pt 1 (Aug): 247-252.
 Abstract
   
  A randomized comparative trial of stavudine (d4T) versus zidovudine (ZDV, AZT) in children
with human immunodeficiency virus infection.
Kline MW, Van Dyke RB, Lindsey JC et al
Pediatrics 1998; 101(2): 214-220.
Abstract

   Conference Reports, Abstracts and Posters

  24-month treatment outcomes amongst HIV-positive children and adolescent patients prescribed stavudine vs. abacavir
A.T. Brennan, M. Maskew, L. Long
{XX International AIDS Conference)
 Abstract
D4T/DDI
       

    Journal Papers, Abstracts, and Commentaries

  FULL-TEXT PDF ARTICLE
Efficacy and safety of stavudine plus didanosine in asymptomatic HIV-infected children
with plasma HIV RNA below 50,000 copies per milliliter.
Mendoza C, Ramos JT, Ciria L, et al. 
HIV Clin Trials 2002 Jan-Feb;3(1):9-16 
 PDF Paper
   
  Combination therapy with stavudine (d4T) plus didanosine (ddI) in children with human
immunodeficiency virus infection.
Kline MW, Van Dyke RB, Lindsey JC et al.
Pediatrics 1999; 103(5): e62.
Abstract
   
  Combination Therapy with Stavudine and Didanosine in Children With Advanced
Human Immunodeficiency virus Infection: Pharmacokinetic Properties, Safety,
and Immunologic and Virologic Effects.
Kline MW, Fletcher CV, Federici ME et al.
Pediatrics 1996; 97(6): 886-890
Abstract
D4T/NVP/3TC
       

    Journal Papers, Abstracts, and Commentaries

 
Pharmacokinetics of Nevirapine, Stavudine and Lamivudine in Indian HIV-infected Children Receiving Generic Fixed Dose Combinations.
Mukherjee A, Singla M, Velpandian T,  et al
Indian Pediatr. 2014 Mar 8;51(3):191-7
 Abstract

A WEEK-IN-REVIEW FEATURED REPORT
A Chewable Pediatric Fixed-Dose Combination Tablet of Stavudine, Lamivudine,
and Nevirapine: Pharmacokinetics and Safety Compared With the Individual
Liquid Formulations in Human Immunodeficiency Virus-Infected Children in Thailand.
Vanprapar N, Cressey TR, Chokephaibulkit K,  et al 
Pediatr Infect Dis J. 2010 May 5.
 Abstract

Limited Sampling Models to Predict the Pharmacokinetics of Nevirapine, Stavudine,
and Lamivudine in HIV-Infected Children Treated With Pediatric Fixed-Dose
Combination Tablets.
 Burger D, Ewings F, Kabamba D, et al  
Ther Drug Monit. 2010 Apr 8.
 Abstract

Fixed Dose Combination of Lamivudine, Stavudine and Nevirapine in the Treatment of
Pediatric HIVInfection: A Preliminary Report.
 Pensi T  
 Indian Pediatr. 2007 Jul;44(7):519-21
 Abstract

Stavudine, nevirapine and ritonavir in stable antiretroviral therapy-experienced children with
human immunodeficiency virus infection.
Yogev R, Lee S,  Wiznia A, et al.
Pediatr Infect Dis J 2002 Feb;21(2):119-125
 Abstract
D4T/NVP/RTV
       

    Journal Papers, Abstracts, and Commentaries

  Stavudine, nevirapine and ritonavir in stable antiretroviral therapy-experienced children with
human immunodeficiency virus infection.
Yogev R, Lee S,  Wiznia A, et al.
Pediatr Infect Dis J 2002 Feb;21(2):119-125
 Abstract
D4T/DDI/IND
       

    Journal Papers, Abstracts, and Commentaries

  A pilot study of combination therapy with indinavir, stavudine (d4T), and didanosine (ddI) in
children infected with the human immunodeficiency virus.
Kline MW, Fletcher CV, Harris AT et al 
Journal of Pediatrics 1998; 132(3 Pt 1): 543-546.
Abstract
Treatment Strategies
       

     Journal Papers, Abstracts, and Commentaries

  A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression.
 Saez-Llorens X, Castaņo E, Rathore M,  et al
Pediatr Infect Dis J. 2015 Apr;34(4):376-82.
Abstract

A prospective study of haematological changes after switching from stavudine to zidovudine-based antiretroviral treatment in HIV-infected children.
Singh A, Hemal A, Agarwal S,  et al
Int J STD AIDS. 2014 Feb 10
Abstract

Lipodystrophy and reversal of facial lipoatrophy in perinatally HIV-infected children and adolescents after
discontinuation of stavudine.
Sawawiboon N, Wittawatmongkol O, Phongsamart W, et al
Int J STD AIDS. 2012 Jul;23(7):497-501
Abstract

 
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