Medical Advocates
Zidovudine (Retrovir)
 
Perinatal Efficacy

ZDV Monotherapy
 ZDV/NVP
ZDV/DDI
ZDV/3TC
 ZDV/LPV/'RTV
ZDV vs HAART


 






 
Perinatal ZDV Main New/Newsworthy  Home Page

Last Update:  April 01, 2017  
  Documents identified with this icon are in Portable Document Format (PDF) and require the Adobe Acrobat Reader

ZDV Monotherapy
 

   Journal Papers, Abstracts, and Commentaries
 
Contribution of different antiretroviral regimens containing zidovudine, lamivudine and ritonavir-boosted lopinavir on HIV viral load reduction during pregnancy.
 Sripan P, Le Coeur S, Ingsrisawang L, et al
Antivir Ther. 2015 Oct 22.
Abstract

Resistance detected by pyrosequencing following zidovudine monotherapy for prevention of HIV-1 mother-to-child-transmission.
Olson SC, Ngo-Giang-Huong N, Beck I,et al
AIDS. 2015 Jul 31;29(12):1467-1471.
 Abstract

Disease Progression Among HIV-Infected Children Who Receive Perinatal Zidovudine
Prophylaxis.
 Berk DR, Falkovitz-Halpern MS, et al  
J Acquir Immune Defic Syndr. 2006 Oct 30;
Abstract
 
Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant
zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized
trial: the Mashi Study.
Thior I, Lockman S, Smeaton LM,et al 
JAMA. 2006 Aug 16;296(7):794-805.
 Abstract

Effectiveness of Short-Term and Long-Term Zidovudine Prophylaxis on Detection of HIV-1
Subtype Ein Human Placenta and Vertical Transmission.
 Bhoopat L, Khunamornpong S, Lerdsrimongkol PSirivatanapa P,et al   
 J Acquir Immune Defic Syndr. 2005 Dec 15;40(5):545-550
 Abstract
ZDV NVP Studies
         
 
Effect of short-course antenatal Zidovudine and single-dose Nevirapine on the BED capture enzyme immunoassay levels in HIV-1 subtype C infection.
 Wang R, Weng J, Moyo S,  et al
 AIDS Res Hum Retroviruses. 2013 Mar 22.
Abstract

Effects of short-course zidovudine on the selection of nevirapine-resistant HIV-1 in women taking single-dose nevirapine.
Micek MA, Blanco AJ, Carlsson J,  et al
 J Infect Dis. 2012 Apr 5.
Abstract

Zidovudine with nevirapine for the prevention of HIV mother-to-child transmission reduces
nevirapine resistance in mothers from the Western Cape, South Africa.
 van Zyl GU, Claassen M, Engelbrecht S, et al 
J Med Virol. 2008 Apr 21;80(6):942-946
 Abstract
 
Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing
mother-to-child transmission of HIV in Africa?
 Leroy V, Sakarovitch C, Cortina-Borja M,
AIDS. 2005 Nov 4;19(16):1865-1875.
Abstract
 
Field efficacy of zidovudine, lamivudine and single-dose nevirapine to prevent
peripartum HIV transmission.
 ANRS 1201/1202 DITRAME PLUS Study Group    
AIDS. 2005 Feb 18;19(3):309-318
 Abstract

Intrapartum and Neonatal Single-Dose Nevirapine Compared with Zidovudine for
Prevention of Mother-to-Child Transmission of HIV-1 in Kampala, Uganda:
Randomized Trial (HIVNET 012)
Guay LA, Musoke P, Fleming T, et al.
 Lancet 1999 Sep 4;354(9181):795-802  
Abstract
  Alternating nevirapine and zidovudine treatment of human  immunodeficiency virus
type 1-infected persons does not prolong nevirapine activity
de Jong MD, Loewenthal M, Boucher CA et al  
 J Infect Dis 1994 Jun;169(6):1346-50
Abstract		  
ZDV DDI Studies
ZDV/DDI vs ZDV/DDI/NVP
ZDV/DDI vs ZDV/DDI/NVP

Efficacy

     Journal Papers, Abstracts, and Commentaries

  Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in
patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial.
Basgoz N, Niu M, Hirsch MS, et al.  
 Ann Intern Med 1996 Jun 15;124(12):1019-30
Abstract 
 
ZDV/DDI/NVP vs ZDV/DDI

Efficacy

      Journal Papers, Abstracts, and Commentaries

  Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in
patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial.  
 D'Aquila RT, Hughes MD, Johnson VA,  et al.  
 Ann Intern Med 1996 Jun 15;124(12):1019-30  
Abstract 		  

 
ZDV/3TC
 
      Journal Papers, Abstracts, and Commentaries
 
 
Contribution of different antiretroviral regimens containing zidovudine, lamivudine and ritonavir-boosted lopinavir on HIV viral load reduction during pregnancy.
 Sripan P, Le Coeur S, Ingsrisawang L, et al
Antivir Ther. 2015 Oct 22.
Abstract
ZDV/LPV/RTV Studies
 
Efficacy

     Journal Papers, Abstracts, and Commentaries
 
  Contribution of different antiretroviral regimens containing zidovudine, lamivudine and ritonavir-boosted lopinavir on HIV viral load reduction during pregnancy.
 Sripan P, Le Coeur S, Ingsrisawang L, et al
Antivir Ther. 2015 Oct 22.
Abstract

Pharmacokinetics and virologic response of zidovudine/lopinavir/ritonavir initiated during
the third trimester of pregnancy.
 Cressey TR, Jourdain G, Rawangban B,  et al
AIDS. 2010 Jul 9
 Abstract 
ZDV vs HAART
 
      Journal Papers, Abstracts, and Commentaries
 
 
Highly Active Antiretroviral Therapy versus Zidovudine for Prevention of Mother-to-Child Transmission
in a Programmatic Setting, Botswana.
 Dryden-Peterson S, Jayeoba O, Hughes MD, et al
J Acquir Immune Defic Syndr. 2011 Jul 22

Use of Zidovudine-sparing HAART in pregnant HIV-infected women in Europe: 2000-2009.
Tariq S, Townsend CL, Cortina-Borja M, et al
J Acquir Immune Defic Syndr. 2011 Apr 14
Abstract

        Conference Reports, Abstracts, and Posters
 

 

Perinatal ZDV Main New/Newsworthy  Home Page

Zidovudine Perinatal Efficacy